{"data":{"sci_version": "1.2", "schema": "https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json", "id": "pmid:34920339", "kind": "science-record", "revision": 3, "content_hash": "sha256:153b2c0f26b9df239c4edd78988141ce4c9f72d9a5df4083ffd86a2d6d8b5e1c", "created_at": "2026-11-01T17:36:38Z", "updated_at": "2026-11-01T21:26:49Z", "generator": {"name": "corpus-assay-engine", "run_id": "reading-sci-2026-11-01"}, "paper": {"state": "complete", "title": "Construction and validation of a risk scoring model for diffuse large B-cell lymphoma based on ferroptosis-related genes and its association with immune infiltration.", "doi": "10.1016/j.tranon.2021.101314", "pmid": "34920339", "authors": ["Dan Xiong", "Mojuan Li", "Chong Zeng"], "journal": "Translational oncology", "year": 2022, "abstract": "BACKGROUNDS: The prognostic significance of ferroptosis-related genes is well known. However, survival- and ferroptosis-related genes are not currently considered in risk scoring models for diffuse large B-cell lymphoma (DLBCL).\nMATERIALS AND METHODS: Ferroptosis regulators and markers were downloaded from the FerrDb database. The transcriptome profiling data were collected from the cancer genome atlas (TCGA). Transcriptome data and corresponding clinical information of DLBCL were downloaded from the gene expression omnibus (GEO). The validation data were downloaded using the UCSC Xena browser. ConsensusClusterPlus was used to categorize DLBCL samples according to gene expression profiles. The survival function was plotted with the Kaplan-Meier plots. The nomogram was built using multivariate logistic regression analysis and the Cox proportional hazards regression model.\nRESULTS: Based on the GSE11318 dataset of 203 samples and 267 ferroptosis-related gene expression profiles, we identified four clusters. A total of 19 survival-related genes were found associated with ferroptosis. The prognostic risk scoring model was constructed based on the regression coefficients. The obtained area under the receiver operating characteristic curve (AUC) values were 0.769, 0.801, and 0.791 for 1-, 3-, and 5-year survival, respectively. DLBCL samples with cluster 2 or cancer stage IV have shorter survival. Correlations between the immune infiltration and risk scores of the 12 immune cells were demonstrated. The response of DLBCL to doxorubicin was effectively validated by the risk scoring model.\nCONCLUSIONS: In this study, a ferroptosis-based risk scoring model for patients with DLBCL was constructed and validated in an independent dataset. This risk score model has a better efficacy in predicting survival compared to clinical characteristics.", "claims": [{"id": "claim-method", "statement": "Univariable Cox regression analysis was carried out to screen the survival- and ferroptosis- related factors. A least absolute shrinkage and selection operator (LASSO)-type regularization method was used to penalize the factor data. The obtained model shrank the coefficients for non-informative factors toward zero, the reduced variance was acquired, and clustering performance was improved. Prognostic risk scoring models associated with ferroptosis-related factors in DLBCL were constructed based on the regression coefficients of these factors.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:34920339", "locator": "sections[10] \"COX-LASSO regression analysis\" paragraph 2", "quote": "Univariable Cox regression analysis was carried out to screen the survival- and ferroptosis- related factors. A least absolute shrinkage and selection operator (LASSO)-type regularization method was used to penalize the factor data. The obtained model shrank the coefficients for non-informative factors toward zero, the reduced variance was acquired, and clustering performance was improved. Prognostic risk scoring models associated with ferroptosis-related factors in DLBCL were constructed based on the regression coefficients of these factors."}], "state": "complete"}, {"id": "claim-data-access", "statement": "Datasets used and/or analyzed in this study can be obtained from the corresponding author upon reasonable request.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:34920339", "locator": "sections[24] \"ack\" paragraph 1", "quote": "Datasets used and/or analyzed in this study can be obtained from the corresponding author upon reasonable request."}], "state": "complete"}, {"id": "claim-target-result", "statement": "The study constructed and externally validated a ferroptosis-based risk scoring model for DLBCL, with AUC values of 0.769, 0.801, and 0.791 for 1-, 3-, and 5-year survival in the development dataset and 0.673, 0.708, and 0.716, respectively, in the independent dataset.", "kind": "qualitative", "target": null, "evidence": [{"asset": "source:pmid:34920339", "locator": "sections[15] \"Identification of ferroptosis and survival-related genes and construction of prognostic risk scoring model\" paragraph 2", "quote": "The prognostic risk scoring model was constructed based on the regression coefficients and calculated as follows, risk Score = -0.006906*DRD4-0.1427*TFAP2C-0.03086*AKR1C3+0.08295*CHAC1+0.2237*ULK2+0.1026*CXCL2-0.2478*GABARAPL1+0.07055*TRIB3-0.01005*CYBB+0.4483*IREB2-0.02139*EPAS1+0.1521*MT1G+0.2654*ATG3-0.06966*CAPG+0.4052*ATF4+0.03599*UBC."}, {"asset": "source:pmid:34920339", "locator": "sections[0] \"Abstract\" paragraph 7", "quote": "The obtained area under the receiver operating characteristic curve (AUC) values were 0.769, 0.801, and 0.791 for 1-, 3-, and 5-year survival, respectively."}, {"asset": "source:pmid:34920339", "locator": "sections[17] \"Validation of the prognostic scoring model for DLBCL and external confirmation of the nomogram\" paragraph 2", "quote": "The GSE10846 expression profile was input into the model, and the risk scores were obtained."}, {"asset": "source:pmid:34920339", "locator": "sections[17] \"Validation of the prognostic scoring model for DLBCL and external confirmation of the nomogram\" paragraph 2", "quote": "The predictive validity of risk scores for 1, 3, and 5 -year survival probability is presented in Fig. 5B, with obtained AUC values of 0.673, 0.708 and 0.716, respectively."}], "state": "complete"}], "gaps": []}, "experiment": {"state": "complete", "objective": "The study constructed and externally validated a ferroptosis-based risk scoring model for DLBCL, with AUC values of 0.769, 0.801, and 0.791 for 1-, 3-, and 5-year survival in the development dataset and 0.673, 0.708, and 0.716, respectively, in the independent dataset.", "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The claim, method and evidence span published with the source article.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:34920339"], "outputs": ["the published estimate and its evidence"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the source data from the named repository", "kind": "data-preparation", "state": "complete", "blocked_on": null, "description": "The GEO series accession resolves and its sample accessions are listed. This lane did not download the dataset or read its licence.", "duration_hours": null, "parameters": {}, "inputs": ["data:geo:GSE10846"], "outputs": ["the source data with its repository provenance"], "instruments": [], "reagents": []}, {"id": "run_analysis", "order": 3, "name": "Run the published analysis", "kind": "analysis", "state": "complete", "blocked_on": null, "description": "Apply the paper's statistical method to the resolved series and compare the result with the published target.", "duration_hours": null, "parameters": {}, "inputs": ["data:geo:GSE10846"], "outputs": ["the replicated result and its comparison"], "instruments": [], "reagents": []}], "materials": [], "instruments": [], "reagents": [], "conditions": {}, "gaps": []}, "data": {"state": "partial", "assets": [{"id": "source:pmid:34920339", "role": "manuscript", "format": "xml", "media_type": "application/xml", "uri": "https://doi.org/10.1016/j.tranon.2021.101314", "sha256": 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"GSM287000", "GSM287001", "GSM287002", "GSM287003", "GSM287004", "GSM287005", "GSM287006", "GSM287007", "GSM287008", "GSM287009", "GSM287010", "GSM287011", "GSM287012", "GSM287013", "GSM287014", "GSM287015", "GSM287016", "GSM287017", "GSM287018", "GSM287019", "GSM287020", "GSM287021", "GSM287022", "GSM287023", "GSM287024", "GSM287025", "GSM287026", "GSM287027", "GSM287028", "GSM287029", "GSM287030", "GSM287031", "GSM287032", "GSM287033", "GSM287034", "GSM287035", "GSM287036", "GSM287037", "GSM287038", "GSM287039", "GSM287040", "GSM287041", "GSM287042", "GSM287043", "GSM287044", "GSM287045", "GSM287046", "GSM287047", "GSM287048", "GSM287049", "GSM287050", "GSM287051", "GSM287052", "GSM287053", "GSM287054", "GSM287055", "GSM287056", "GSM287057", "GSM287058", "GSM287059", "GSM287060", "GSM287061", "GSM287062", "GSM287063", "GSM287064", "GSM287065", "GSM287066", "GSM287067", "GSM287068", "GSM287069", "GSM287070", "GSM287071", "GSM287072", "GSM287073", "GSM287074", "GSM287075", "GSM287076", "GSM287077", "GSM287078", "GSM287079", "GSM287080", "GSM287081", "GSM287082", "GSM287083", "GSM287084", "GSM287085", "GSM287086", "GSM287087", "GSM287088", "GSM287089", "GSM287090", "GSM287091", "GSM287092", "GSM287093", "GSM287094"], "sample_count": 406, "group_sizes": null, "group_sizes_basis": null, "platform": "570;6400", "taxon": "Homo sapiens", "title": "Molecular subtypes of DLBCL have distinct chromosomal aberrations", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}], "gaps": ["asset:data:geo:GSE10846 not downloaded", "asset:data:geo:GSE10846 licence not read", "asset:data:geo:GSE11318 not downloaded", "asset:data:geo:GSE11318 licence not read"]}, "analysis": {"state": "complete", "methods": [{"id": "method-1", "family": "survival_analysis", "specific": "cox_proportional_hazards", "label": "Survival analysis", "dsl_operations": ["cox_ph"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["time_to_event_with_censoring"], "evidence": {"score": 1.0, "band": "verbatim", "quote": "Univariable Cox regression analysis was carried out to screen the survival- and ferroptosis- related factors. A least absolute shrinkage and selection operator (LASSO)-type regularization method was used to penalize the factor data. The obtained model shrank the coefficients for non-informative factors toward zero, the reduced variance was acquired, and clustering performance was improved. Prognostic risk scoring models associated with ferroptosis-related factors in DLBCL were constructed based on the regression coefficients of these factors."}}, {"id": "method-2", "family": "survival_analysis", "specific": "kaplan_meier", "label": "Survival analysis", "dsl_operations": ["survival_km"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["time_to_event_with_censoring"], "evidence": {"score": 0.7, "band": "medium", "quote": "Kaplan-Meier"}}, {"id": "method-3", "family": "regression_modelling", "specific": "logistic", "label": "Regression modelling", "dsl_operations": ["glm_logit_fit"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["predictors_and_outcome"], "evidence": {"score": 0.7, "band": "medium", "quote": "logistic regression"}}], "targets": [], "gaps": []}, "capability": {"state": "complete", "requirements": [{"capability_id": "capability:computational_analysis", "label": "Computational analysis platform", "assay_families": ["meta_analysis", "machine_learning", "survival_analysis", "statistical_regression", "pca", "molecular_docking", "network_analysis", "differential_expression", "gwas"], "availability_state": "owned", "tier_unlocked": "R1", "candidate": "Automated Assays Laravel application and simulated adapters"}], "gaps": []}, "readiness": {"state": "complete", "tier": "R1", "blocking_axis": "none", "blocked_on": "nothing:replicable_now", "axes": {"method": {"tier": "R1", "expressible": true, "required_operations": ["cox_ph"], "missing_operations": [], "basis": "The paper names the method it used and the corpus's method extractor maps it onto the DSL catalogue: cox_proportional_hazards."}, "capability": {"tier": "R1", "capability_id": "capability:computational_analysis", "availability_state": "owned", "basis": "The computational analysis is owned. The physical bench the paper used is not, so a physical validation cannot be run here."}, "data": {"tier": "R1", "reachable": true, "accessions": ["GSE11318", "GSE10846"], "resolved_accessions": ["GSE11318", "GSE10846"], "statements": ["Datasets used and/or analyzed in this study can be obtained from the corresponding author upon reasonable request."], "basis": "The paper names GSE11318, GSE10846 in gene expression omnibus (GEO) and the accession resolves in the repository. No dataset was downloaded and no licence was read."}}, "can_run": {"dsl_operations": ["cox_ph"], "assets": ["source:pmid:34920339", "data:geo:GSE10846"], "steps": ["run_analysis"]}, "must_build": {"dsl_operations": [], "converters": [], "readers": [], "capabilities": [], "data_gaps": ["data:geo:GSE10846"]}, "gaps": []}, "review": {"state": "partial", "machine_critique": {"kind": "extraction_review", "reader": {"model": "MiniMax-M3.1-Flash", "provider": "minimax", "provider_family": "minimax", "read_at": "2026-11-01T17:11:45Z", "independence": "single_reader"}, "evidence_check": {"method": "verbatim", "availability": "verbatim"}, "calls": 5, "usage": {"prompt_tokens": 9180, "completion_tokens": 2226, "cached_tokens": 264}}, "human_critique": null, "stages": [{"id": "extraction", "state": "complete", "reader": "MiniMax-M3.1-Flash", "provider": "minimax"}], "gaps": ["review.independent_reader", "review.machine_critique", "review.human_critique"]}, "execution": {"state": "absent", "status": "not_run", "mode": null, "runs": [], "gaps": ["execution.not_run"]}, "provenance": {"entities": [{"id": "pmid:34920339", "type": "paper", "label": "pmid:34920339"}, {"id": "source:pmid:34920339", "type": "manuscript", "label": "PMID 34920339 full text"}, {"id": "data:geo:GSE10846", "type": "dataset", "label": "GEO GSE10846"}], "activities": [{"id": "activity-reading-sci-2026-11-01", "type": "classification", "used": [{"id": "pmid:34920339", "type": "paper", "label": "pmid:34920339"}, {"id": "source:pmid:34920339", "type": "manuscript", "label": "PMID 34920339 full text"}, {"id": "data:geo:GSE10846", "type": "dataset", "label": "GEO GSE10846"}], "agent": "agent:corpus-assay-engine"}, {"id": "activity-read-34920339", "type": "extraction", "used": ["source:pmid:34920339"], "agent": "agent:minimax-reader"}, {"id": "activity-resolve-GSE10846", "type": "accession_resolution", "used": ["data:geo:GSE10846"], "agent": "agent:corpus-assay-engine"}], "agents": [{"id": "agent:corpus-assay-engine", "type": "software", "label": "Corpus assay engine"}, {"id": "agent:minimax-reader", "type": "software", "label": "MiniMax literature reader"}], "source_run_id": "reading-sci-2026-11-01", "dsl_catalogue_fingerprint": "343fb30756ba6ec3", "capability_table_fingerprint": "2cb3e42f047d2ecf", "snapshot_id": "ba34b49490d9bfaf"}, "lineage": {"parent_id": "pmid:34920339", "parent_hash": "sha256:f6b5fb9f157c5c6243ac263b549197087aa381c0c328067c015f239f8cb53847", "fork_of": null, "generation": 2}, "gaps": ["asset:data:geo:GSE10846 licence not read", "asset:data:geo:GSE10846 not downloaded", "asset:data:geo:GSE11318 licence not read", "asset:data:geo:GSE11318 not downloaded", "execution.not_run", "review.human_critique", "review.independent_reader", "review.machine_critique"], "assays": [{"role": "analysis", "definition_id": "survival_analysis", "definition_version": "f2132e96ae6c7a4e", "definition_digest": null, "required_operations": ["cox_ph"], "support_state": "supported", "source_hashes": {"dsl_catalogue": "f2132e96ae6c7a4e"}, "confidence": 1.0, "evidence": ["Univariable Cox regression analysis was carried out to screen the survival- and ferroptosis- related factors. A least absolute shrinkage and selection operator (LASSO)-type regularization method was used to penalize the factor data. The obtained model shrank the coefficients for non-informative factors toward zero, the reduced variance was acquired, and clustering performance was improved. Prognostic risk scoring models associated with ferroptosis-related factors in DLBCL were constructed based on the regression coefficients of these factors."], "order_basis": "analysis_only", "id": "assay:1"}]},"meta":{"api_version":"v1","automation_ladder_snapshot":"ba34b49490d9bfaf","automation_ladder_caveats":["Method extraction is rule-based and has no hand-judged accuracy sample. Evidence bands order textual support; method agreement intervals are null (n=0), never probabilities. Work-type validation does not validate methods.","Operation coverage describes only explicitly named methods. It does not prove a complete protocol, compatible parameters, successful compilation or re-execution. Unrecognised or ambiguous methods require review.","Data reachability is a textual accession or public-data statement. No dataset was downloaded or checked for access, completeness or licence.","Capabilities are planning states seeded from the dated equipment register. No bench ownership, completed quote or partner booking is inferred. Procurement counts are dependencies, not guaranteed replications or financial returns.","Tier and blocker counts are deterministic assessments of this corpus, not measured agreement. R3 is reserved for procurement; unresolved methods and data require human work (R4). The most restrictive axis wins, with capability, method, data as tie-breaks. Resolving one blocker can leave another at the same tier."],"engine":"corpus_engine","engine_provider":"rule_based_v1+lex99e1195c7d6f","run_id":"run-20261023T122449232913","source":"esearch","source_detail":"PubMed mirror biomed_pubmed (read-only)","run_status":"complete","imported_at":"2026-11-03T20:16:52+00:00","generated_at":"2026-11-04T03:14:02+00:00","total_papers":5529,"total_assays_tracked":29,"automatable_assay_families":6,"validated":true,"caveat_count":9,"blocking_caveats":5,"caveats":[{"code":"low_evidence_dominates","basis":["4,152 of 5,529 classifications (75.1%) matched no cue evidence and sit at the 0.05 floor.","34 of 230 data_only calls (14.8%) are in that group."],"claim":"Work type and confidence bands","gloss":"Most records were classified from their title and framing alone, with assay-cue coverage at zero.","detail":"Most classifications in this run rest on no matched evidence at all. At the evidence floor the work type comes from title framing and a fixed prior, not from anything in the paper, so the published work-type split should be read as a rough triage signal rather than a measured distribution. The impact is bounded but not removed: since 2026-10-23 the engine excludes floor-confidence records from the shortlist entirely and publishes them separately as held out, so the recommendation is unaffected even though the census is.","status":"unverified","severity":"high"},{"code":"runtime_is_modelled","basis":["Runtime is summed from published per-assay hour figures. Timing awaits the first executed replication.","4,407 of 5,529 records (79.7%) model to 0.00 hours because no assay was matched, which the ranking then reads as \"cheapest\".","0 of 10 shortlisted records carry a 0.00-hour estimate."],"claim":"Estimated replication runtime","gloss":"The hour figures are estimates built from assay mentions; timing awaits the first executed replication.","detail":"The hour figures are a cost model derived from the bench steps implied by each matched assay family. The first executed replication will supply measured timing. Records without an assay match currently receive a zero-hour model value.","status":"unverified","severity":"high"},{"code":"signal_score_without_citations","basis":["5,529 of 5,529 records (100.0%) have no citation count from the source metadata."],"claim":"Signal score","gloss":"The signal score uses publication-type weight because the mirror supplied zero citation counts.","detail":"The source supplied no citation counts for any record in this run, so the signal score is publication-type weight only. The citation term of the ranking is inert here, and the shortlist is ordered by publication type alone.","status":"unverified","severity":"high"},{"code":"abstract_absent","basis":["1,667 of 5,529 records (30.2%) carry no abstract at all."],"claim":"Evidence base for classification","gloss":"Some records contain a title and publication type only, defining the available classification evidence.","detail":"Where the mirror contains a title and publication types only, those fields define the classifier evidence. A methods section is required for fuller automated and human review.","status":"unverified","severity":"medium"},{"code":"classifier_agreement_measured","basis":["Published two-way decision agreement 77.7% (310 of 399 decidable records) from a stratified hand-check of 438 real records.","Three-way diagnostic agreement 73.9% (288 of 390 decidable records).","data_only agreement 75.2% (100 of 133 decidable).","48 record(s) could not be decided from title and abstract and were excluded from the denominator.","56 analysis-only records were published under another work type, so the data_only share is not an upper bound."],"claim":"Published automatable decision","gloss":"This figure has been checked against a human reading the same papers, so we know how often it is right.","detail":"The published automatable / not-automatable distribution comes from a rule-based classifier that was hand-checked against a fixed ground-truth definition. The agreement rates below are measured, not estimated. The three-way work type remains a diagnostic and is reported separately.","status":"measured","severity":"high"},{"code":"llm_comparison_not_measured","basis":["rule_based_v1+lex99e1195c7d6f produced 5,529 of 5,529 classifications.","Measured on 438 labelled records; these are RULE-BASED figures, not model results."],"claim":"Rule-based versus LLM agreement","gloss":"Every number here is the rule engine’s own. Model comparison begins when a working API credential is connected and measured.","detail":"The published two-way decision agreed with a human reading on 310 of 399 decidable records (77.7%). The diagnostic three-way label agreed on 288 of 390 decidable records (73.9%). Every percentage in this run belongs to the rule engine. Model comparison begins when a working API credential is connected and measured.","status":"not_measured","severity":"high"},{"code":"confidence_is_a_band","basis":["low band: 135 of 210 hand-judged records were correct, 64.3% [57.6, 70.5] (95% CI).","medium band: 80 of 104 hand-judged records were correct, 76.9% [68.0, 84.0] (95% CI).","high band: 73 of 76 hand-judged records were correct, 96.0% [89.0, 98.7] (95% CI).","A fitted calibrated probability was built, measured and withdrawn: it overstated held-out accuracy and reorders nothing."],"claim":"Confidence band and evidence score","gloss":"The confidence band carries a measured accuracy interval; 0.85 represents relative rank strength.","detail":"Confidence on this run is a BAND plus its measured accuracy interval. The number stored alongside each record is a monotone evidence score that orders records; 0.85 represents relative rank strength. A fitted probability was withdrawn after it overstated held-out accuracy. Threshold on the band.","status":"measured","severity":"medium"},{"code":"three_way_split_is_diagnostic","basis":["The corpus is published at the two-way decision: automatable or not-automatable. The three-way split (data_only / physical / mixed) is published as a diagnostic with its measured reliability attached, not as a claim, because the rule engine's `mixed` call cannot be defended.","The engine called 22 record(s) mixed; 10 matched the human judgement (45.5%, 95% CI 26.9-65.3).","The engine's `mixed` call is right on 10/22 hand-judged records (45.5%, 95% CI 26.9%-65.3%); a constant `physical` guess scores 36.4%.","The engine's `mixed` call does not reliably beat a constant `physical` guess on the hand-judged records it labels mixed.","The sign of that difference flips between two independent samples, so the three-way refinement is not demonstrably informative.","The mixed stratum contributes a disproportionate share of errors relative to its size.","At title-only depth the physical/mixed split collapses: a title says that work was done, not whether it was also analysed."],"claim":"The published decision is two-way","gloss":"The three-way split is shown for diagnosis only. The published split is two ways.","detail":"Count and filter the corpus on automatable versus not-automatable. The data_only / physical / mixed split remains an internal engine diagnostic because the mixed call has lower measured reliability.","status":"measured","severity":"medium"},{"code":"automatable_flag_unproven","basis":["6 of 29 assay families are marked automatable now: meta_analysis, machine_learning, survival_analysis, pca, molecular_docking, differential_expression.","The flag is a rule over assay family and work type; validation begins with the first executed replication.","It inherits the 75.2% data_only agreement rate, because the flag requires the record to be analysis-only."],"claim":"Automatable now","gloss":"This flag marks assay families the rules classify as data-only. The first executed replication will validate it.","detail":"This flag marks families the rules consider replicable from data alone. Its validity depends on the analysis-only classification and will be measured through an executed replication.","status":"unverified","severity":"medium"}],"confidence_policy":"band_with_measured_interval","confidence_contract":{"policy":"band_with_measured_interval","summary":"Confidence is reported as a BAND with a measured accuracy interval. The raw evidence score supplies monotone ordering. A fitted point estimate was withdrawn after it overstated held-out accuracy.","evidence_score":"A monotone evidence score in [0,1] built from cue mass, axis separation and text coverage. Use it to order records. Interpret 0.85 as relative rank strength.","confidence_band":"low | medium | high. Consumers threshold on this value.","band_accuracy":"Wilson 95% interval on the measured agreement of the hand-judged records in this band.","calibrated_confidence":"WITHDRAWN. Reintroduction requires held-out evidence demonstrating reliable estimates across every bin."},"band_accuracy":{"low":{"n":210,"low":0.576,"band":"low","high":0.7046,"agree":135,"accuracy":0.6429},"high":{"n":76,"low":0.8903,"band":"high","high":0.9865,"agree":73,"accuracy":0.9605},"medium":{"n":104,"low":0.6795,"band":"medium","high":0.8397,"agree":80,"accuracy":0.7692}},"provider":"rule_based_v1+lex99e1195c7d6f","lexicon_id":"99e1195c7d6f","contract_published_at":"2026-10-23T12:25:29.022232+00:00","confidence_is_band":true,"confidence_is_probability":false,"decision_taxonomy":"two_way","decidable_fraction_two_way":0.8854,"decidable_fraction_two_way_low":0.8565,"decidable_fraction_two_way_high":0.9143,"decidable_fraction_three_way":0.8586,"decidable_fraction_three_way_low":0.8287,"decidable_fraction_three_way_high":0.8884,"decidable_population":5529,"validation_sample_size":438,"three_way_cost_fraction":0.0268,"three_way_cost_records":148,"decision_counts":{"automatable":230,"not_automatable":5299},"decision_split":{"automatable":{"count":230,"share":0.04159884246699222},"not_automatable":{"count":5299,"share":0.9584011575330078}},"diagnostic_work_type_counts":{"mixed":24,"physical":5275,"data_only":230}}}