Corpus Engine Towards a reproducible .science file.
← All .science files

pmid:12962150

Semiquantitative RT-PCR method coupled to capillary electrophoresis to study 5alpha-reductase mRNA isozymes in rat ventral prostate in different androgen status.

Molecular and cellular biochemistry · 2003 doi:10.1023/a:1024902419502

Paper

partial

Experiment

partial

Data

partial

Analysis

absent

Execution

absent

Execution evidence has not yet been added to this .science file. Explore its methods, data and open questions to plan the next step.
Record details sci_version · id · kind · revision · content_hash · schema · created_at · updated_at · generator
id
pmid:12962150
kind
science-record
content_hash
sha256:711eddb2dfdc62d4d46c0568c9a93872f4e93e89610a3e63c7516b2cf8af0161
schema
https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json
created_at
2026-11-01T10:25:48Z
updated_at
2026-11-01T10:25:48Z
generator object · 3 fields
name
corpus-assay-engine
converter
sep_to_sci_v1
source_package_schema
urn:bntrg:sep:1.0.0
paper object · 10 fields
state
partial
title
Semiquantitative RT-PCR method coupled to capillary electrophoresis to study 5alpha-reductase mRNA isozymes in rat ventral prostate in different androgen status.
doi
10.1023/a:1024902419502
pmid
12962150
authors
null
journal
Molecular and cellular biochemistry
year
2003
abstract
null
claims array · 1 item
[0] object · 6 fields
id
claim-1
statement
relative mRNA level of the 5alpha-reductase type 2 isozyme in rat ventral prostate
kind
qualitative
state
blocked
target object · 4 fields
value
null
unit
null
tolerance
null
source
null
evidence array · 0 items
gaps array · 2 items
[0]
abstract
[1]
authors
experiment object · 8 fields
state
partial
objective
relative mRNA level of the 5alpha-reductase type 2 isozyme in rat ventral prostate
steps array · 3 items
[0] object · 13 fields
id
read_published_estimate
order
1
name
Read the published estimate and its interval from the source
kind
other
state
complete
blocked_on
null
description
The number a replication must land on, and the sentence it came from.
parameters object · 0 fields
inputs array · 1 item
[0]
source:pmid:12962150
outputs array · 1 item
[0]
the published estimate, its unit and its interval
instruments array · 0 items
reagents array · 0 items
[1] object · 13 fields
id
obtain_source_data
order
2
name
Obtain the study data behind the published pooled estimate
kind
data-preparation
state
blocked
blocked_on
data:accession_absent
description
The published estimate cannot be recomputed without the data the review pooled.
parameters object · 0 fields
inputs array · 0 items
outputs array · 1 item
[0]
the pooled study data with its provenance
instruments array · 0 items
reagents array · 0 items
[2] object · 13 fields
id
provide_capability_animal_model
order
3
name
Provide In-vivo animal model work
kind
computational
state
blocked
blocked_on
capability:animal_model
description
The corpus blocks this paper on this capability, so the experiment cannot start until it is available.
parameters object · 0 fields
inputs array · 0 items
outputs array · 0 items
instruments array · 0 items
reagents array · 0 items
materials array · 2 items
[0]
the study data pooled behind the published estimate in pmid:12962150
[1]
the analysis programme that recomputes the published estimate
instruments array · 0 items
reagents array · 0 items
conditions object · 0 fields
gaps array · 2 items
[0]
step:obtain_source_data blocked on data:accession_absent
[1]
step:provide_capability_animal_model blocked on capability:animal_model
data object · 3 fields
state
partial
assets array · 3 items
[0] object · 15 fields
id
source:pmid:12962150
role
manuscript
format
txt
media_type
text/plain
uri
https://doi.org/10.1023/a:1024902419502
sha256
sha256:c3d8c197c8d120c8ccf543a154eb95604cb2ddddf74e0fefb799c9311102e8ce
bytes
null
access
unknown
state
declared
reader
null
reader_status
reader_required
identifier
10.1023/a:1024902419502
version
null
note
Source read by the package builder: abstract_only.
structure object · 1 field
access_state
abstract_only
[1] object · 15 fields
id
materials:the study data pooled behind the published estimate in pmid:12962150
role
raw
format
unknown
media_type
application/octet-stream
uri
null
sha256
null
bytes
null
access
unknown
state
unavailable
reader
null
reader_status
unknown
identifier
null
version
null
note
the study data pooled behind the published estimate in pmid:12962150
structure object · 2 fields
material_kind
dataset
access_state
not_identified
[2] object · 15 fields
id
materials:the analysis programme that recomputes the published estimate
role
code
format
unknown
media_type
application/octet-stream
uri
null
sha256
null
bytes
null
access
unknown
state
unavailable
reader
null
reader_status
unknown
identifier
null
version
null
note
the analysis programme that recomputes the published estimate
structure object · 2 fields
material_kind
code
access_state
absent
gaps array · 3 items
[0]
asset:materials:the analysis programme that recomputes the published estimate not verified
[1]
asset:materials:the study data pooled behind the published estimate in pmid:12962150 not verified
[2]
asset:source:pmid:12962150 not verified
analysis object · 4 fields
state
absent
methods array · 0 items
targets array · 0 items
gaps array · 4 items
[0]
method
[1]
method.evidence_rejected
[2]
operations
[3]
targets
capability object · 3 fields
state
partial
requirements array · 1 item
[0] object · 6 fields
capability_id
capability:animal_model
label
In-vivo animal model work
assay_families array · 1 item
[0]
animal_model
availability_state
unavailable
candidate
null
gaps array · 1 item
[0]
capability:capability:animal_model unavailable
readiness object · 8 fields
state
blocked
tier
R4
blocking_axis
capability
blocked_on
capability:animal_model
axes object · 3 fields
method object · 4 fields
axis
method
tier
R4
blocker
method:not_determinable
detail object · 3 fields
outcome
not_determinable
reason
The evidence this method was read from does not name the method under the corpus's own vocabulary.
basis
The phrase the method was read from names something else, so the claim is withdrawn and a person has to read the paper before it can be programmed.
capability object · 4 fields
axis
capability
tier
R4
blocker
capability:animal_model
detail object · 5 fields
families array · 1 item
[0]
animal_model
capability_id
capability:animal_model
availability_state
unavailable
considered array · 2 items
[0] object · 4 fields
family
animal_model
capability_id
capability:bench_workcell
availability_state
purchasable
tier_unlocked
R3
[1] object · 4 fields
family
animal_model
capability_id
capability:animal_model
availability_state
unavailable
tier_unlocked
R4
basis
The equipment register names no animal-facility capability at any gate. In-vivo work needs a specialist facility and an ethical approval, which is a collaboration rather than a purchase.
data object · 4 fields
axis
data
tier
R4
blocker
data:accession_absent
detail object · 3 fields
applies
true
reachable
false
basis
The record names no repository accession and no data-availability statement, so the source data has to be requested from the authors.
can_run object · 3 fields
dsl_operations array · 0 items
assets array · 0 items
steps array · 1 item
[0]
read_published_estimate
must_build object · 5 fields
dsl_operations array · 0 items
converters array · 0 items
readers array · 2 items
[0]
txt
[1]
unknown
capabilities array · 1 item
[0]
capability:animal_model
data_gaps array · 3 items
[0]
source:pmid:12962150
[1]
materials:the study data pooled behind the published estimate in pmid:12962150
[2]
materials:the analysis programme that recomputes the published estimate
gaps array · 2 items
[0]
capability:animal_model
[1]
method:not_determinable
review object · 5 fields
state
partial
machine_critique object · 7 fields
status
blocked
providers array · 2 items
[0] object · 7 fields
provider
minimax
model
MiniMax-M3.1-Flash
prompt_version
peer-review-reading-v1
prompt_hash
7e7a5a1191c97e6b55c552c9e1779b1bfb05a0220ef3bfa96c8dcb82c1877a5f
source_hash
c3d8c197c8d120c8ccf543a154eb95604cb2ddddf74e0fefb799c9311102e8ce
raw_response_sha256
sha256:2314b31ddba37ec05143f82366907772b043375204c8e9ab4fd490b386c62e38
raw_response_chars
1768
[1] object · 7 fields
provider
qwen_remote
model
qwen3.8:27b-codex128k
prompt_version
peer-review-reading-v1
prompt_hash
5332ea68993cb01c2b46426fade8e86444d33b5d1b3d69d03cefd47224b62840
source_hash
c3d8c197c8d120c8ccf543a154eb95604cb2ddddf74e0fefb799c9311102e8ce
raw_response_sha256
sha256:984716a1c6668e21d71c6b55bfaf9c9018d326a7fbff60b456a078f5900cb7ce
raw_response_chars
1761
agreement
false
disagreements object · 3 fields
target_result object · 2 fields
minimax
Testosterone controls the expression of the 5alpha-reductase type 2 isozyme in rat ventral prostate; the direction and magnitude of the relative mRNA-level change are unclear from the supplied text.
qwen_remote
unknown
physical_methods object · 2 fields
minimax array · 2 items
[0]
Collection of ventral prostate tissue from rats with different androgen statuses
[1]
Measurement of 5alpha-reductase isozyme mRNA levels
qwen_remote array · 2 items
[0]
semiquantitative PCR
[1]
laser-induced fluorescence capillary electrophoresis (LIF-CE)
source_claims object · 2 fields
minimax array · 3 items
[0]
The study presents measurements of mRNA levels of steroid 5alpha-reductase isozymes in the ventral prostate of rats with different androgen statuses.
[1]
Both 5alpha-reductase isozymes are expressed in the prostate.
[2]
The authors report that testosterone controls the expression of the 5alpha-reductase type 2 isozyme in rat prostate.
qwen_remote array · 3 items
[0]
The authors present measurements of mRNA levels of steroid 5alpha-R isozymes in the ventral prostate of rats of different androgen status.
[1]
They used a novel method combining the high specificity of semiquantitative PCR with the sensitivity of laser-induced fluorescence capillary electrophoresis (LIF-CE).
[2]
They demonstrated that testosterone controls the expression of the 5alpha-R2 isozyme in rat prostate.
blinded
true
human_critique object · 5 fields
status
not_run
reviewer
null
signed_at
null
conflict_checked
false
commentary
null
stages array · 7 items
[0] object · 4 fields
key
target_materials
status
pending
reason
null
evidence
null
[1] object · 4 fields
key
independent_readings
status
blocked
reason
The independent readings are incomplete or disagree; the source evidence must resolve the difference.
evidence object · 1 field
provider_errors array · 0 items
[2] object · 4 fields
key
source_resolution
status
pending
reason
null
evidence
null
[3] object · 4 fields
key
protocol_reconstruction
status
pending
reason
null
evidence
null
[4] object · 4 fields
key
control_execution
status
pending
reason
null
evidence
null
[5] object · 4 fields
key
control_comparison
status
pending
reason
null
evidence
null
[6] object · 4 fields
key
publication
status
pending
reason
null
evidence
null
gaps array · 2 items
[0]
review.human_critique
[1]
review.machine_critique.blocked
execution object · 5 fields
state
absent
status
not_run
mode
null
runs array · 0 items
gaps array · 1 item
[0]
execution.not_run
provenance object · 7 fields
entities array · 1 item
[0] object · 3 fields
id
package:3f890a1bb470ba9bcbd261e12e5ec2a9b7b8389e5bbe284fe303a0ffa0c524c9
type
sep_package
label
SEP v1 package for pmid:12962150
activities array · 1 item
[0] object · 4 fields
id
activity:conversion:pmid:12962150
type
conversion
used array · 1 item
[0]
package:3f890a1bb470ba9bcbd261e12e5ec2a9b7b8389e5bbe284fe303a0ffa0c524c9
agent
agent:corpus-assay-engine
agents array · 3 items
[0] object · 3 fields
id
agent:minimax
type
model
label
minimax
[1] object · 3 fields
id
agent:qwen_remote
type
model
label
qwen_remote
[2] object · 3 fields
id
agent:corpus-assay-engine
type
software
label
Corpus assay engine
source_run_id
run-20261023T122449232913
dsl_catalogue_fingerprint
343fb30756ba6ec3
capability_table_fingerprint
2cb3e42f047d2ecf
snapshot_id
ba34b49490d9bfaf
lineage object · 4 fields
parent_id
pmid:12962150
parent_hash
sha256:91d5299ccdac4124df61de88ca1bd737fa37041e8371317f53d47bd95b6e5fbd
fork_of
null
gaps array · 17 items
[0]
abstract
[1]
asset:materials:the analysis programme that recomputes the published estimate not verified
[2]
asset:materials:the study data pooled behind the published estimate in pmid:12962150 not verified
[3]
asset:source:pmid:12962150 not verified
[4]
authors
[5]
capability:animal_model
[6]
capability:capability:animal_model unavailable
[7]
execution.not_run
[8]
method
[9]
method.evidence_rejected
[10]
method:not_determinable
[11]
operations
[12]
review.human_critique
[13]
review.machine_critique.blocked
[14]
step:obtain_source_data blocked on data:accession_absent
[15]
step:provide_capability_animal_model blocked on capability:animal_model
[16]
targets
Complete file
{"sci_version": "1.0", "schema": "https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json", "id": "pmid:12962150", "kind": "science-record", "revision": 2, "content_hash": "sha256:711eddb2dfdc62d4d46c0568c9a93872f4e93e89610a3e63c7516b2cf8af0161", "created_at": "2026-11-01T10:25:48Z", "updated_at": "2026-11-01T10:25:48Z", "generator": {"name": "corpus-assay-engine", "converter": "sep_to_sci_v1", "source_package_schema": "urn:bntrg:sep:1.0.0"}, "paper": {"state": "partial", "title": "Semiquantitative RT-PCR method coupled to capillary electrophoresis to study 5alpha-reductase mRNA isozymes in rat ventral prostate in different androgen status.", "doi": "10.1023/a:1024902419502", "pmid": "12962150", "authors": null, "journal": "Molecular and cellular biochemistry", "year": 2003, "abstract": null, "claims": [{"id": "claim-1", "statement": "relative mRNA level of the 5alpha-reductase type 2 isozyme in rat ventral prostate", "kind": "qualitative", "state": "blocked", "target": {"value": null, "unit": null, "tolerance": null, "source": null}, "evidence": []}], "gaps": ["abstract", "authors"]}, "experiment": {"state": "partial", "objective": "relative mRNA level of the 5alpha-reductase type 2 isozyme in rat ventral prostate", "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate and its interval from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The number a replication must land on, and the sentence it came from.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:12962150"], "outputs": ["the published estimate, its unit and its interval"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the study data behind the published pooled estimate", "kind": "data-preparation", "state": "blocked", "blocked_on": "data:accession_absent", "description": "The published estimate cannot be recomputed without the data the review pooled.", "duration_hours": null, "parameters": {}, "inputs": [], "outputs": ["the pooled study data with its provenance"], "instruments": [], "reagents": []}, {"id": "provide_capability_animal_model", "order": 3, "name": "Provide In-vivo animal model work", "kind": "computational", "state": "blocked", "blocked_on": "capability:animal_model", "description": "The corpus blocks this paper on this capability, so the experiment cannot start until it is available.", "duration_hours": null, "parameters": {}, "inputs": [], "outputs": [], "instruments": [], "reagents": []}], "materials": ["the study data pooled behind the published estimate in pmid:12962150", "the analysis programme that recomputes the published estimate"], "instruments": [], "reagents": [], "conditions": {}, "gaps": ["step:obtain_source_data blocked on data:accession_absent", "step:provide_capability_animal_model blocked on capability:animal_model"]}, "data": {"state": "partial", "assets": [{"id": "source:pmid:12962150", "role": "manuscript", "format": "txt", "media_type": "text/plain", "uri": "https://doi.org/10.1023/a:1024902419502", "sha256": "sha256:c3d8c197c8d120c8ccf543a154eb95604cb2ddddf74e0fefb799c9311102e8ce", "bytes": null, "access": "unknown", "state": "declared", "reader": null, "reader_status": "reader_required", "identifier": "10.1023/a:1024902419502", "version": null, "note": "Source read by the package builder: abstract_only.", "structure": {"access_state": "abstract_only"}}, {"id": "materials:the study data pooled behind the published estimate in pmid:12962150", "role": "raw", "format": "unknown", "media_type": "application/octet-stream", "uri": null, "sha256": null, "bytes": null, "access": "unknown", "state": "unavailable", "reader": null, "reader_status": "unknown", "identifier": null, "version": null, "note": "the study data pooled behind the published estimate in pmid:12962150", "structure": {"material_kind": "dataset", "access_state": "not_identified"}}, {"id": "materials:the analysis programme that recomputes the published estimate", "role": "code", "format": "unknown", "media_type": "application/octet-stream", "uri": null, "sha256": null, "bytes": null, "access": "unknown", "state": "unavailable", "reader": null, "reader_status": "unknown", "identifier": null, "version": null, "note": "the analysis programme that recomputes the published estimate", "structure": {"material_kind": "code", "access_state": "absent"}}], "gaps": ["asset:materials:the analysis programme that recomputes the published estimate not verified", "asset:materials:the study data pooled behind the published estimate in pmid:12962150 not verified", "asset:source:pmid:12962150 not verified"]}, "analysis": {"state": "absent", "methods": [], "targets": [], "gaps": ["method", "method.evidence_rejected", "operations", "targets"]}, "capability": {"state": "partial", "requirements": [{"capability_id": "capability:animal_model", "label": "In-vivo animal model work", "assay_families": ["animal_model"], "availability_state": "unavailable", "tier_unlocked": "R4", "candidate": null}], "gaps": ["capability:capability:animal_model unavailable"]}, "readiness": {"state": "blocked", "tier": "R4", "blocking_axis": "capability", "blocked_on": "capability:animal_model", "axes": {"method": {"axis": "method", "tier": "R4", "blocker": "method:not_determinable", "detail": {"outcome": "not_determinable", "reason": "The evidence this method was read from does not name the method under the corpus's own vocabulary.", "basis": "The phrase the method was read from names something else, so the claim is withdrawn and a person has to read the paper before it can be programmed."}}, "capability": {"axis": "capability", "tier": "R4", "blocker": "capability:animal_model", "detail": {"families": ["animal_model"], "capability_id": "capability:animal_model", "availability_state": "unavailable", "considered": [{"family": "animal_model", "capability_id": "capability:bench_workcell", "availability_state": "purchasable", "tier_unlocked": "R3"}, {"family": "animal_model", "capability_id": "capability:animal_model", "availability_state": "unavailable", "tier_unlocked": "R4"}], "basis": "The equipment register names no animal-facility capability at any gate. In-vivo work needs a specialist facility and an ethical approval, which is a collaboration rather than a purchase."}}, "data": {"axis": "data", "tier": "R4", "blocker": "data:accession_absent", "detail": {"applies": true, "reachable": false, "basis": "The record names no repository accession and no data-availability statement, so the source data has to be requested from the authors."}}}, "can_run": {"dsl_operations": [], "assets": [], "steps": ["read_published_estimate"]}, "must_build": {"dsl_operations": [], "converters": [], "readers": ["txt", "unknown"], "capabilities": ["capability:animal_model"], "data_gaps": ["source:pmid:12962150", "materials:the study data pooled behind the published estimate in pmid:12962150", "materials:the analysis programme that recomputes the published estimate"]}, "gaps": ["capability:animal_model", "method:not_determinable"]}, "review": {"state": "partial", "machine_critique": {"status": "blocked", "providers": [{"provider": "minimax", "model": "MiniMax-M3.1-Flash", "prompt_version": "peer-review-reading-v1", "prompt_hash": "7e7a5a1191c97e6b55c552c9e1779b1bfb05a0220ef3bfa96c8dcb82c1877a5f", "source_hash": "c3d8c197c8d120c8ccf543a154eb95604cb2ddddf74e0fefb799c9311102e8ce", "raw_response_sha256": "sha256:2314b31ddba37ec05143f82366907772b043375204c8e9ab4fd490b386c62e38", "raw_response_chars": 1768}, {"provider": "qwen_remote", "model": "qwen3.8:27b-codex128k", "prompt_version": "peer-review-reading-v1", "prompt_hash": "5332ea68993cb01c2b46426fade8e86444d33b5d1b3d69d03cefd47224b62840", "source_hash": "c3d8c197c8d120c8ccf543a154eb95604cb2ddddf74e0fefb799c9311102e8ce", "raw_response_sha256": "sha256:984716a1c6668e21d71c6b55bfaf9c9018d326a7fbff60b456a078f5900cb7ce", "raw_response_chars": 1761}], "target_providers": null, "agreement": false, "disagreements": {"target_result": {"minimax": "Testosterone controls the expression of the 5alpha-reductase type 2 isozyme in rat ventral prostate; the direction and magnitude of the relative mRNA-level change are unclear from the supplied text.", "qwen_remote": "unknown"}, "physical_methods": {"minimax": ["Collection of ventral prostate tissue from rats with different androgen statuses", "Measurement of 5alpha-reductase isozyme mRNA levels"], "qwen_remote": ["semiquantitative PCR", "laser-induced fluorescence capillary electrophoresis (LIF-CE)"]}, "source_claims": {"minimax": ["The study presents measurements of mRNA levels of steroid 5alpha-reductase isozymes in the ventral prostate of rats with different androgen statuses.", "Both 5alpha-reductase isozymes are expressed in the prostate.", "The authors report that testosterone controls the expression of the 5alpha-reductase type 2 isozyme in rat prostate."], "qwen_remote": ["The authors present measurements of mRNA levels of steroid 5alpha-R isozymes in the ventral prostate of rats of different androgen status.", "They used a novel method combining the high specificity of semiquantitative PCR with the sensitivity of laser-induced fluorescence capillary electrophoresis (LIF-CE).", "They demonstrated that testosterone controls the expression of the 5alpha-R2 isozyme in rat prostate."]}}, "agreement_basis": null, "blinded": true}, "human_critique": {"status": "not_run", "reviewer": null, "signed_at": null, "conflict_checked": false, "commentary": null}, "stages": [{"key": "target_materials", "status": "pending", "reason": null, "evidence": null}, {"key": "independent_readings", "status": "blocked", "reason": "The independent readings are incomplete or disagree; the source evidence must resolve the difference.", "evidence": {"provider_errors": []}}, {"key": "source_resolution", "status": "pending", "reason": null, "evidence": null}, {"key": "protocol_reconstruction", "status": "pending", "reason": null, "evidence": null}, {"key": "control_execution", "status": "pending", "reason": null, "evidence": null}, {"key": "control_comparison", "status": "pending", "reason": null, "evidence": null}, {"key": "publication", "status": "pending", "reason": null, "evidence": null}], "gaps": ["review.human_critique", "review.machine_critique.blocked"]}, "execution": {"state": "absent", "status": "not_run", "mode": null, "runs": [], "gaps": ["execution.not_run"]}, "provenance": {"entities": [{"id": "package:3f890a1bb470ba9bcbd261e12e5ec2a9b7b8389e5bbe284fe303a0ffa0c524c9", "type": "sep_package", "label": "SEP v1 package for pmid:12962150"}], "activities": [{"id": "activity:conversion:pmid:12962150", "type": "conversion", "used": ["package:3f890a1bb470ba9bcbd261e12e5ec2a9b7b8389e5bbe284fe303a0ffa0c524c9"], "agent": "agent:corpus-assay-engine"}], "agents": [{"id": "agent:minimax", "type": "model", "label": "minimax"}, {"id": "agent:qwen_remote", "type": "model", "label": "qwen_remote"}, {"id": "agent:corpus-assay-engine", "type": "software", "label": "Corpus assay engine"}], "source_run_id": "run-20261023T122449232913", "dsl_catalogue_fingerprint": "343fb30756ba6ec3", "capability_table_fingerprint": "2cb3e42f047d2ecf", "snapshot_id": "ba34b49490d9bfaf"}, "lineage": {"parent_id": "pmid:12962150", "parent_hash": "sha256:91d5299ccdac4124df61de88ca1bd737fa37041e8371317f53d47bd95b6e5fbd", "fork_of": null, "generation": 2}, "gaps": ["abstract", "asset:materials:the analysis programme that recomputes the published estimate not verified", "asset:materials:the study data pooled behind the published estimate in pmid:12962150 not verified", "asset:source:pmid:12962150 not verified", "authors", "capability:animal_model", "capability:capability:animal_model unavailable", "execution.not_run", "method", "method.evidence_rejected", "method:not_determinable", "operations", "review.human_critique", "review.machine_critique.blocked", "step:obtain_source_data blocked on data:accession_absent", "step:provide_capability_animal_model blocked on capability:animal_model", "targets"]}