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pmid:23986641

Effect of transarterial chemoembolization with miriplatin plus epirubicin on local control of hepatocellular carcinoma: a retrospective comparison with miriplatin monotherapy

OncoTargets and therapy · 2013 doi:10.2147/OTT.S49443

Paper

partial

Experiment

partial

Data

partial

Analysis

partial

Execution

absent

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Record details sci_version · id · kind · revision · content_hash · schema · created_at · updated_at · generator
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Effect of transarterial chemoembolization with miriplatin plus epirubicin on local control of hepatocellular carcinoma: a retrospective comparison with miriplatin monotherapy
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10.2147/OTT.S49443
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23986641
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OncoTargets and therapy
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2013
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the 1-year local tumour control rate for transarterial chemoembolisation with miriplatin plus low-dose epirubicin, against miriplatin alone
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The local control rates at 6 months and 1 year were 87% and 65% for the miriplatin plus low-dose epirubicin group, and 61% and 43% for the miriplatin group, respectively.
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We retrospectively analyzed the records of patients who underwent TACE using miriplatin plus low-dose epirubicin (30 patients, 61 nodules, August 2011–March 2012) and control patients who underwent TACE using miriplatin alone (36 patients, 70 nodules, June 2010–July 2011). The local control rate was compared between the two groups using the Kaplan–Meier estimator and the log-rank test. Factors affecting local tumor recurrence were analyzed using multivariate logistic regression analysis. Treatment-related toxicity was evaluated using the Common Terminology Criteria for Adverse Events.
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At 1 year, the local tumour control rate was 65% for transarterial chemoembolisation with miriplatin plus low-dose epirubicin, compared with 43% for miriplatin alone.
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At 1 year, the local tumor control rate was 65% for TACE with miriplatin plus low-dose epirubicin versus 43% for TACE with miriplatin alone. The reported overall comparison favored the combination group (P = 0.038).
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