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pmid:26217786

Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis.

Jyothi Padiadpu · Priyanka Baloni · Nagasuma Chandra

Data in brief · 2015 doi:10.1016/j.dib.2015.05.006

Paper

complete

Experiment

partial

Data

partial

Analysis

partial

Execution

absent

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Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis.
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10.1016/j.dib.2015.05.006
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Jyothi Padiadpu
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Priyanka Baloni
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Nagasuma Chandra
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Data in brief
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2015
abstract
The global variations in the gene expression pattern of drug treated (½X) and laboratory evolved drug-resistant strains (2XR and 4XR) of Mycobacterium smegmatis were obtained and compared with the M. smegmatis mc(2) 155 (WT) strain. The genes exhibiting two-fold change and p-value <0.05 under the treated conditions have been considered as differentially expressed genes (DEGs). Overall, the numbers of DEGs observed are 1529 in ½X (596-up, 933-down), 1381 (899-up, 482-down) in 2XR and 716 in 4XR (267-up, 449-down) conditions. The data is publicly available through the GEO database with accession number GSE64132.
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The global variations in the gene expression pattern of drug treated (½X) and laboratory evolved drug-resistant strains (2XR and 4XR) of Mycobacterium smegmatis were obtained and compared with the M. smegmatis mc2 155 (WT) strain.
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Overall, the numbers of DEGs observed are 1529 in ½X (596—up, 933—down), 1381 (899—up, 482—down) in 2XR and 716 in 4XR (267—up, 449—down) conditions.
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Gene expression profile of wild-type and isoniazid resistant strains of Mycobacterium smegmatis
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