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pmid:26697328

Expression data of HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the presence of BubR1 siRNA.

Yusuke Nakayama · Akihiro Ohashi

Genomics data · 2015 doi:10.1016/j.gdata.2015.08.002

Paper

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Experiment

complete

Data

partial

Analysis

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Execution

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Expression data of HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the presence of BubR1 siRNA.
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Yusuke Nakayama
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Akihiro Ohashi
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Genomics data
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The molecular mechanism responsible for cell fate after mitotic slippage is unclear. We investigated the postmitotic effects of different mitotic aberrations (Ohashi et al. [1]), misaligned chromosomes produced by CENP-E siRNA (siCENP-E), and monopolar spindles resulting from Eg5 siRNA (siEg5) (Miki et al. [2]). To determine which signaling pathways contribute to the postmitotic effect of siCENP-E in the presence of siBubR1 (siCENP-E + siBubR1) compared with siEg5 + siBubR1, we performed comprehensive gene expression analysis using microarray comparisons [1]. The microarray data have been deposited in NCBI's Gene Expression Omnibus (GEO) and are accessible through GEO Series accession number GSE67905.
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Expression data in HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the presence of BubR1 siRNA
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