p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo: Computational analysis of next-generation sequencing data.

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Moreover, the binding of p53 was associated to a series of specific motifs on the DNA, which were directly inferred from the data. Here, we describe in detail the computational analysis of the datasets associated with our study (Tonelli et al., Oncotarget 6 (2015), 24611-26), deposited in the GEO archive (accession code GSE71180), and we provide the R scripts needed to generated the figures of the paper.", "claims": [{"id": "claim-data-access", "statement": "Direct link to deposited data\nhttp://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71180.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:26981355", "locator": "sections[2] \"Direct link to deposited data\" paragraphs 1-2", "quote": "Direct link to deposited data\nhttp://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71180."}], "state": "complete"}], "gaps": []}, "experiment": {"state": "complete", "objective": null, "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The claim, method and evidence span published with the source article.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:26981355"], "outputs": ["the published estimate and its evidence"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the source data from the named repository", "kind": "data-preparation", "state": "complete", "blocked_on": null, "description": "The GEO series accession resolves and its sample accessions are listed. 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