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pmid:26981370

Microarray analysis of microRNA expression in bone marrow-derived progenitor cells from mice with type 2 diabetes.

Jie-Mei Wang · Kezhong Zhang

Genomics data · 2016 doi:10.1016/j.gdata.2015.11.020

Paper

complete

Experiment

complete

Data

partial

Analysis

absent

Execution

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Microarray analysis of microRNA expression in bone marrow-derived progenitor cells from mice with type 2 diabetes.
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10.1016/j.gdata.2015.11.020
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Jie-Mei Wang
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Kezhong Zhang
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Genomics data
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Bone-marrow derived vascular precursors are an important endogenous repair reservoir for vascular repair and neovascularization [1]. Therapies of stem/progenitor cells targeting on angiogenesis are considered hopeful solutions for tissue repair and regeneration. However, the dysfunction of patient-derived progenitor cells has been implicated in diabetes [2], which limited the efficacy of autologous cell therapies in the clinic [3,4]. MicroRNAs are important gene regulators whose functions remain largely unknown. In this project we reported the different microRNA expression profiles in bone marrow-derived progenitor cells from type 2 diabetic mice and their normal controls using microRNA array analysis. All microarray data are available at the Gene Expression Omnibus (GEO) at NCBI (http://www.ncbi.nlm.nih.gov/geo), under accession number GSE72616.
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