Data on endogenous bovine ovarian follicular cells peptides and small proteins obtained through Top-down High Resolution Mass Spectrometry.

{"sci_version": "1.2", "schema": "https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json", "id": "pmid:28603764", "kind": "science-record", "revision": 5, "content_hash": "sha256:5fd02fdf602eb2dad8bf51aa3e16d9cc2b0925507deb317ae21fd19d8a1abc54", "created_at": "2026-11-01T15:40:26Z", "updated_at": "2026-11-01T18:48:47Z", "generator": {"name": "corpus-assay-engine", "run_id": "reading-sci-2026-11-01"}, "paper": {"state": "complete", "title": "Data on endogenous bovine ovarian follicular cells peptides and small proteins obtained through Top-down High Resolution Mass Spectrometry.", "doi": "10.1016/j.dib.2017.05.042", "pmid": "28603764", "authors": ["Valérie Labas", "Ana-Paula Teixeira-Gomes", "Laura Bouguereau", "Audrey Gargaros", "Lucie Spina", "Aurélie Marestaing", "Svetlana Uzbekova"], "journal": "Data in brief", "year": 2017, "abstract": "The endogenous peptides and small proteins extracted from bovine ovarian follicular cells (oocytes, cumulus and granulosa cells) were identified by Top-down High Resolution Mass Spectrometry (TD-HR-MS/MS) in order to annotate peptido- and proteoforms detected using qualitative and quantitative profiling method based on ICM-MS (Intact Cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry). The description and analysis of these Top-down MS data in the context of oocyte quality biomarkers research are available in the original research article of Labas et al. (2017) http://dx.doi.org/10.1016/j.jprot.2017.03.027[1]. Raw data derived from this peptidomic/proteomic analysis have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository (dataset identifier PXD004892). Here, we described the inventory of all identified peptido- and proteoforms including their biochemical and structural features, and functional annotation of correspondent proteins. This peptide/protein inventory revealed that TD-HR-MS/MS was appropriate method for both global and targeted proteomic analysis of ovarian tissues, and it can be further employed as a reference for other studies on follicular cells including single oocytes.", "claims": [{"id": "claim-data-access", "statement": "Raw data derived from this peptidomic/proteomic analysis have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository (dataset identifier PXD004892).", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:28603764", "locator": "sections[0] \"Abstract\" paragraph 1", "quote": "Raw data derived from this peptidomic/proteomic analysis have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository (dataset identifier PXD004892)."}], "state": "complete"}, {"id": "claim-target-result", "statement": "The study found that “TD-HR-MS/MS was appropriate method for both global and targeted proteomic analysis of ovarian tissues, and it can be further employed as a reference for other studies on follicular cells including single oocytes.” No statistical method is specified; the source data are available through PRIDE under dataset identifier PXD004892.", "kind": "qualitative", "target": null, "evidence": [{"asset": "source:pmid:28603764", "locator": "sections[0] \"Abstract\" paragraph 1", "quote": "This peptide/protein inventory revealed that TD-HR-MS/MS was appropriate method for both global and targeted proteomic analysis of ovarian tissues, and it can be further employed as a reference for other studies on follicular cells including single oocytes."}, {"asset": "source:pmid:28603764", "locator": "sections[0] \"Abstract\" paragraph 1", "quote": "Raw data derived from this peptidomic/proteomic analysis have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository (dataset identifier PXD004892)."}], "state": "complete"}], "gaps": []}, "experiment": {"state": "complete", "objective": "The study found that “TD-HR-MS/MS was appropriate method for both global and targeted proteomic analysis of ovarian tissues, and it can be further employed as a reference for other studies on follicular cells including single oocytes.” No statistical method is specified; the source data are available through PRIDE under dataset identifier PXD004892.", "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The claim, method and evidence span published with the source article.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:28603764"], "outputs": ["the published estimate and its evidence"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the source data from the named repository", "kind": "data-preparation", "state": "complete", "blocked_on": null, "description": "The GEO series accession resolves and its sample accessions are listed. 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