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pmid:31372389

RNA sequencing data of cultured primary rat Müller cells, the spontaneously immortalized rat Müller cell line, SIRMu-1, and the SV40-transformed rat Müller cell line, rMC-1.

Thaksaon Kittipassorn · Cameron D Haydinger · John P M Wood · Teresa Mammone · Robert J Casson · Daniel J Peet

Data in brief · 2019 doi:10.1016/j.dib.2019.103721

Paper

complete

Experiment

complete

Data

partial

Analysis

partial

Execution

absent

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Record details sci_version · id · kind · revision · content_hash · schema · created_at · updated_at · generator
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title
RNA sequencing data of cultured primary rat Müller cells, the spontaneously immortalized rat Müller cell line, SIRMu-1, and the SV40-transformed rat Müller cell line, rMC-1.
doi
10.1016/j.dib.2019.103721
pmid
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authors array · 6 items
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Thaksaon Kittipassorn
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Cameron D Haydinger
[2]
John P M Wood
[3]
Teresa Mammone
[4]
Robert J Casson
[5]
Daniel J Peet
journal
Data in brief
year
2019
abstract
Müller cells (MCs), the major type of glial cell of the vertebrate retina, have a vital role in retinal physiology and pathology. They provide structural and functional support for retinal neurons, including photoreceptors, and are implicated in various retinal diseases. Primary and immortalized MCs are important experimental tools for MC research. Here we present high throughput RNA sequencing data of 3 populations of cultured rat MCs: primary cells, the spontaneously immortalized rat MC line, SIRMu-1, and the SV40-transformed rat MC line, rMC-1. These data were deposited in NCBI Gene Expression Omnibus (GEO ID: GSE123161). For data analysis, interpretation and discussion, please refer to the research article, "Characterization of the novel spontaneously immortalized rat Müller cell line SIRMu-1" (Kittipassorn et al., 2019). This dataset is valuable for gaining insight into gene expression profiles of different types of cultured MCs and the roles of MCs in health and disease.
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The data relating to this article are stored in NCBI Gene Expression Omnibus [3] (GEO ID: GSE123161), including: fastq files containing raw sequencing reads (one per sample, 12 in total); csv files containing numbers of reads per gene (un-normalized and unfiltered, one per sample, 12 in total); a tsv file containing TMM-normalized log2 counts per million reads for all 12 samples.
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title
Characterization of the novel spontaneously immortalized rat Müller cell line SIRMu-1
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The data relating to this article are stored in NCBI Gene Expression Omnibus [3] (GEO ID: GSE123161), including: fastq files containing raw sequencing reads (one per sample, 12 in total); csv files containing numbers of reads per gene (un-normalized and unfiltered, one per sample, 12 in total); a tsv file containing TMM-normalized log2 counts per million reads for all 12 samples.
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RNA sequencing data of cultured primary rat Müller cells, the spontaneously immortalized
[1]
Müller cells, the spontaneously immortalized rat Müller cell line, SIRMu-1, and the SV40-tran
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cell line, SIRMu-1, and the SV40-transformed rat Müller cell line, rMC-1.
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sequencing data of 3 populations of cultured rat MCs: primary cells, the spontaneously immort
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hput RNA sequencing data of 3 populations of cultured rat MCs: primary cells, the spontaneously im
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ent, approximately every 7 days. The SIRMu-1 cell line was cultured in the same medium as the primary MCs with t
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Complete file
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