Identification of hub genes related to prognosis in glioma.

{"sci_version": "1.2", "schema": "https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json", "id": "pmid:32406502", "kind": "science-record", "revision": 6, "content_hash": "sha256:78b38b98987f76526c05fed249aae159108208a4fe455aedc836d9cb7bdbcb5c", "created_at": "2026-11-01T15:41:01Z", "updated_at": "2026-11-01T21:23:14Z", "generator": {"name": "corpus-assay-engine", "run_id": "reading-sci-2026-11-01"}, "paper": {"state": "complete", "title": "Identification of hub genes related to prognosis in glioma.", "doi": "10.1042/BSR20193377", "pmid": "32406502", "authors": ["Delong Zhang", "Jinxia Zhao", "Chengzheng Han", "Xiaocen Liu", "Jun Liu", "Hui Yang"], "journal": "Bioscience reports", "year": 2020, "abstract": "Glioma, a common malignant tumor of the central nervous system, has high invasiveness. The objective of the present study was to identify genes playing an important role in the development of glioma and to reveal their potential research value. Conjoint analysis on the GSE16011 dataset in the Gene Expression Omnibus (GEO) database and the 'Messenger RNA Expression Microarray of Diffuse Gliomas and Controls' dataset and 'RNA sequencing of Diffuse Gliomas' dataset in the Chinese Glioma Genome Atlas (CGGA) database is carried out in the study. The weighted correlation network analysis (WGCNA) was used to carry out co-expression analysis on the GSE16011. Finally, 24 genes significantly related to grade and prognosis were obtained. In addition, there is no report about CACNG2, JPH3, TUBB6 (tubulin β 6 class V), NRSN1, FAM19A2, NALCN, CDH18, GNAL on glioma.", "claims": [{"id": "claim-method", "statement": "Genes with likelihood test P<0.001 and consistent trends in two datasets were screened, with 2682 genes in total regarded as result C (Figure 4B, additionally shown in Supplementary ResultC.csv).", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:32406502", "locator": "sections[14] \"Survival analysis (result C)\" paragraph 2", "quote": "Genes with likelihood test P<0.001 and consistent trends in two datasets were screened, with 2682 genes in total regarded as result C (Figure 4B, additionally shown in Supplementary ResultC.csv)."}], "state": "complete"}, {"id": "claim-data-access", "statement": "The datasets analyzed during the current study are available in the CGGA repository [data3, data4 http://www.cgga.org.cn/download.jsp]. 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