pmid:32782267

A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins.

Kae Hwan Sim · Lillian Chia-Yi Liu · Hwee Tong Tan · Kelly Tan · Daniel Ng · Wei Zhang · Yuansheng Yang · Stephen Tate · Xuezhi Bi

Scientific data · 2020 doi:10.1038/s41597-020-00594-z

Paper

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title

A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins.

doi

10.1038/s41597-020-00594-z

pmid

32782267

authors array · 9 items

[0]

Kae Hwan Sim

[1]

Lillian Chia-Yi Liu

[2]

Hwee Tong Tan

[3]

Kelly Tan

[4]

Daniel Ng

[5]

Wei Zhang

[6]

Yuansheng Yang

[7]

Stephen Tate

[8]

Xuezhi Bi

journal

Scientific data

year

2020

abstract

Sequential window acquisition of all theoretical fragment-ion spectra (SWATH) is a data-independent acquisition (DIA) strategy that requires a specific spectral library to generate unbiased and consistent quantitative data matrices of all peptides. SWATH-MS is a promising approach for in-depth proteomic profiling of Chinese hamster Ovary (CHO) cell lines, improving mechanistic understanding of process optimization, and real-time monitoring of process parameters in biologics R&D and manufacturing. However, no spectral library for CHO cells is publicly available. Here we present a comprehensive CHO global spectral library to measure the abundance of more than 10,000 proteins consisting of 199,102 identified peptides from a CHO-K1 cell proteome. The robustness, accuracy and consistency of the spectral library were validated for high confidence in protein identification and reproducible quantification in different CHO-derived cell lines, instrumental setups and downstream processing samples. The availability of a comprehensive SWATH CHO global spectral library will facilitate detailed characterization of upstream and downstream processes, as well as quality by design (QbD) in biomanufacturing. The data have been deposited to ProteomeXchange (PXD016047).

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The raw DDA data files for library generation, the search result (group files), the CHO spectral library, and the SWATH-MS acquisition data applied in the current study have been deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org)34via the PRIDE partner repository35,36 with the data set identifier PXD01604728.

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A comprehensive CHO SWATH-MS spectral library for accurate quantitative profiling of 10k proteins

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Comparison of the proteome coverage between CHO global spectral library, 1D library and the latest proteomic studies on CHO-DG44 and CHO-S cells.

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Coverage of the CHO global spectral library

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Comparison of the proteome coverage between CHO global spectral library, 1D library and the latest proteomic studies on CHO-DG44 and CHO-S cells.

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DDA files #

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CHO-DG44 stationary13

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5,593

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50,194

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Proteome Discoverer

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CHO-S exponential13

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Proteome Discoverer

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Proteome Discoverer

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Comparison of CHO global spectral library and uncalibrated combined-search spectral library in CHO-K1 WCL SWATH-MS data.

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Calibrated retention time in CHO global spectral library

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Comparison of CHO global spectral library and uncalibrated combined-search spectral library in CHO-K1 WCL SWATH-MS data.

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14,061

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Details of three LC-MS instrumental setups for the SWATH-MS acquisition of CHO-K1 WCL samples.

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Portability of the CHO global spectral library

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Details of three LC-MS instrumental setups for the SWATH-MS acquisition of CHO-K1 WCL samples.

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[0] array · 4 items

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NF6600 (TripleTOF 6600 coupled to nanoflow LC)

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CF5600 (TripleTOF 5600 + coupled to capillary flow LC)

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MF6600 (TripleTOF 6600 coupled to microflow LC)

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SCIEX TripleTOF 5600+

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SWATH-MS

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SWATH-MS

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SWATH-MS

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Waters CSH C181 mm × 150 mm

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5 µL/min

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50 µL/min

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95 min

[3]

90 min

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The protein areas of the 152 HCPs quantified in the DSP mAb samples.

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Robustness of protein identification and quantification in CHO HCCF and HCPs in DSP mAb samples

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Online-only Table 1

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The protein areas of the 152 HCPs quantified in the DSP mAb samples.

rows array · 153 items

[0] array · 12 items

[0]

Protein Id

[1]

Protein Description

[2]

MW[Cal.]

[3]

[4]

OM_MEAN

[5]

OM_STDEV

[6]

PrA_MEAN

[7]

PrA_STDEV

[8]

CEX_MEAN

[9]

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[10]

AEX_MEAN

[11]

AEX_STDEV

[1] array · 12 items

[0]

NP_001230908.1

[1]

Tubulin alpha-1b chain

[2]

49872.57

[3]

4.94

[4]

3.32E + 05

[5]

3.27E + 03

[6]

7.22E + 03

[7]

6.02E + 03

[8]

4.89E + 03

[9]

2.63E + 03

[10]

5.02E + 03

[11]

7.77E + 02

[2] array · 12 items

[0]

NP_001230912.1

[1]

Aminoacyl trna synthase complex-interacting multifunctional protein 2

[2]

35386.3

[3]

7.69

[4]

4.49E + 04

[5]

2.56E + 03

[6]

9.17E + 02

[7]

2.03E + 02

[8]

1.21E + 02

[9]

1.51E + 02

[10]

8.43E + 01

[11]

1.03E + 02

[3] array · 12 items

[0]

NP_001230968.1

[1]

Elongation factor 2

[2]

94879.53

[3]

6.41

[4]

2.76E + 05

[5]

1.25E + 03

[6]

7.25E + 03

[7]

3.12E + 03

[8]

6.66E + 03

[9]

2.89E + 02

[10]

3.30E + 04

[11]

3.47E + 04

[4] array · 12 items

[0]

NP_001231030.1

[1]

Tubulin beta-5 chain

[2]

49098.5

[3]

4.78

[4]

1.74E + 05

[5]

6.85E + 03

[6]

1.53E + 04

[7]

4.50E + 03

[8]

8.98E + 03

[9]

1.86E + 03

[10]

3.73E + 03

[11]

5.01E + 02

[5] array · 12 items

[0]

NP_001231196.1

[1]

Aminoacyl trna synthase complex-interacting multifunctional protein 1

[2]

39699.01

[3]

9.37

[4]

7.32E + 04

[5]

2.43E + 03

[6]

4.62E + 03

[7]

1.54E + 03

[8]

4.15E + 03

[9]

3.58E + 02

[10]

1.78E + 04

[11]

3.30E + 03

[6] array · 12 items

[0]

NP_001231202.1

[1]

Golgi apparatus protein 1 precursor

[2]

128275.35

[3]

6.34

[4]

1.09E + 05

[5]

1.25E + 03

[6]

4.90E + 03

[7]

2.88E + 03

[8]

9.20E + 03

[9]

3.19E + 03

[10]

1.82E + 03

[11]

7.37E + 02

[7] array · 12 items

[0]

NP_001231331.1

[1]

Elongation factor 1-alpha 1

[2]

51088.98

[3]

9.1

[4]

9.01E + 05

[5]

2.23E + 04

[6]

4.14E + 04

[7]

4.97E + 03

[8]

3.96E + 03

[9]

1.43E + 03

[10]

4.94E + 03

[11]

1.11E + 03

[8] array · 12 items

[0]

NP_001231783.1

[1]

Glyceraldehyde-3-phosphate dehydrogenase

[2]

36823.87

[3]

8.49

[4]

3.71E + 06

[5]

5.56E + 04

[6]

3.12E + 03

[7]

9.96E + 02

[8]

3.64E + 03

[9]

1.26E + 03

[10]

4.50E + 03

[11]

1.84E + 03

[9] array · 12 items

[0]

NP_001233603.1

[1]

Beta-2-microglobulin precursor

[2]

13159.28

[3]

6.89

[4]

3.73E + 05

[5]

7.79E + 03

[6]

2.49E + 03

[7]

3.94E + 02

[8]

2.36E + 03

[9]

7.15E + 02

[10]

2.67E + 03

[11]

4.81E + 02

[10] array · 12 items

[0]

NP_001233622.2

[1]

Protein disulfide-isomerase precursor

[2]

56286.34

[3]

4.77

[4]

1.52E + 06

[5]

0.00E + 00

[6]

4.46E + 03

[7]

1.69E + 03

[8]

3.17E + 03

[9]

1.35E + 03

[10]

2.55E + 03

[11]

4.42E + 02

[11] array · 12 items

[0]

NP_001233630.1

[1]

Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1

[2]

37597.95

[3]

5.61

[4]

2.01E + 04

[5]

2.05E + 02

[6]

1.16E + 03

[7]

1.36E + 02

[8]

2.89E + 03

[9]

2.74E + 03

[10]

9.19E + 02

[11]

3.78E + 02

[12] array · 12 items

[0]

NP_001233634.1

[1]

Trifunctional purine biosynthetic protein adenosine-3

[2]

111688.02

[3]

6.45

[4]

1.21E + 05

[5]

1.63E + 03

[6]

3.00E + 03

[7]

9.37E + 02

[8]

6.61E + 03

[9]

2.50E + 03

[10]

4.98E + 03

[11]

3.23E + 03

[13] array · 12 items

[0]

NP_001233654.1

[1]

Phosphoglycerate kinase 1

[2]

46112.78

[3]

8.02

[4]

4.09E + 05

[5]

9.42E + 03

[6]

7.58E + 03

[7]

3.47E + 03

[8]

5.90E + 03

[9]

3.62E + 03

[10]

1.21E + 04

[11]

8.00E + 03

[14] array · 12 items

[0]

NP_001233658.1

[1]

Heat shock cognate 71 kda protein

[2]

71436.1

[3]

5.24

[4]

9.90E + 05

[5]

1.70E + 03

[6]

7.60E + 03

[7]

8.28E + 03

[8]

3.71E + 03

[9]

1.67E + 03

[10]

2.60E + 03

[11]

3.55E + 02

[15] array · 12 items

[0]

NP_001233662.1

[1]

T-complex protein 1 subunit alpha

[2]

61483.7

[3]

5.71

[4]

4.73E + 05

[5]

4.55E + 03

[6]

1.17E + 04

[7]

2.24E + 03

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2.75E + 03

[9]

1.15E + 03

[10]

4.32E + 03

[11]

2.34E + 03

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[0]

NP_001233668.1

[1]

Endoplasmic reticulum chaperone bip precursor

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72320.76

[3]

5.07

[4]

6.88E + 06

[5]

1.36E + 05

[6]

8.76E + 03

[7]

5.77E + 03

[8]

2.19E + 04

[9]

2.21E + 04

[10]

8.08E + 03

[11]

3.65E + 03

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[0]

NP_001233670.1

[1]

Hypoxia up-regulated protein 1 precursor

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110471.62

[3]

5.09

[4]

3.43E + 05

[5]

7.59E + 03

[6]

5.95E + 03

[7]

1.69E + 03

[8]

6.10E + 03

[9]

1.63E + 03

[10]

1.03E + 04

[11]

2.59E + 03

[18] array · 12 items

[0]

NP_001233673.1

[1]

Glutathione s-transferase p 1

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23222.26

[3]

7.64

[4]

1.62E + 06

[5]

4.19E + 04

[6]

9.83E + 03

[7]

2.55E + 03

[8]

2.60E + 03

[9]

8.25E + 02

[10]

6.29E + 03

[11]

9.27E + 02

[19] array · 12 items

[0]

NP_001233694.1

[1]

Peroxiredoxin-1

[2]

22005.86

[3]

8.22

[4]

8.50E + 06

[5]

8.64E + 04

[6]

3.60E + 04

[7]

1.86E + 04

[8]

9.51E + 03

[9]

2.96E + 03

[10]

6.97E + 03

[11]

4.04E + 03

[20] array · 12 items

[0]

NP_001233703.1

[1]

Protein disulfide-isomerase a3 precursor

[2]

55844.01

[3]

5.98

[4]

7.40E + 05

[5]

1.00E + 04

[6]

1.79E + 03

[7]

7.72E + 01

[8]

3.03E + 03

[9]

2.08E + 03

[10]

2.21E + 03

[11]

5.15E + 02

[21] array · 12 items

[0]

NP_001233750.1

[1]

Heat shock protein hsp 90-alpha

[2]

81056.75

[3]

4.96

[4]

8.92E + 05

[5]

2.16E + 03

[6]

6.99E + 03

[7]

2.39E + 03

[8]

8.07E + 03

[9]

2.29E + 03

[10]

3.73E + 03

[11]

1.68E + 03

[22] array · 12 items

[0]

XP_027243210.1

[1]

Heat shock protein hsp 90-beta isoform x11

[2]

80061.51

[3]

4.97

[4]

2.74E + 06

[5]

1.63E + 04

[6]

2.50E + 04

[7]

1.98E + 04

[8]

1.10E + 04

[9]

7.37E + 03

[10]

7.83E + 03

[11]

7.34E + 03

[23] array · 12 items

[0]

XP_027243827.1

[1]

T-complex protein 1 subunit delta

[2]

59603.81

[3]

8.24

[4]

4.07E + 05

[5]

3.40E + 03

[6]

8.46E + 03

[7]

2.71E + 03

[8]

8.78E + 03

[9]

3.65E + 03

[10]

2.24E + 03

[11]

7.59E + 02

[24] array · 12 items

[0]

XP_027243857.1

[1]

Malate dehydrogenase, cytoplasmic

[2]

36934.45

[3]

6.17

[4]

3.58E + 05

[5]

9.43E + 03

[6]

3.64E + 03

[7]

1.53E + 03

[8]

2.93E + 03

[9]

4.38E + 02

[10]

2.79E + 03

[11]

9.83E + 02

[25] array · 12 items

[0]

XP_027243958.1

[1]

Peptidyl-prolyl cis-trans isomerase a isoform x2

[2]

18135.48

[3]

8.44

[4]

5.95E + 05

[5]

9.10E + 03

[6]

1.92E + 03

[7]

7.67E + 02

[8]

3.08E + 03

[9]

1.31E + 03

[10]

6.03E + 03

[11]

3.23E + 03

[26] array · 12 items

[0]

XP_027244682.1

[1]

Lipoprotein lipase isoform x2

[2]

52415.96

[3]

7.94

[4]

1.39E + 05

[5]

2.87E + 03

[6]

1.30E + 04

[7]

7.08E + 03

[8]

7.10E + 03

[9]

8.53E + 02

[10]

6.92E + 03

[11]

3.47E + 03

[27] array · 12 items

[0]

XP_027245386.1

[1]

Transketolase

[2]

68892.71

[3]

7.56

[4]

7.23E + 05

[5]

6.94E + 03

[6]

8.12E + 03

[7]

4.97E + 03

[8]

5.61E + 03

[9]

1.13E + 03

[10]

5.71E + 03

[11]

2.30E + 03

[28] array · 12 items

[0]

XP_027246103.1

[1]

Clusterin

[2]

49430.24

[3]

5.52

[4]

3.08E + 06

[5]

1.64E + 05

[6]

8.56E + 04

[7]

8.95E + 03

[8]

5.42E + 03

[9]

3.52E + 02

[10]

4.63E + 03

[11]

2.33E + 03

[29] array · 12 items

[0]

XP_027246161.1

[1]

Cathepsin b

[2]

37487.37

[3]

5.73

[4]

1.61E + 06

[5]

2.16E + 04

[6]

7.52E + 03

[7]

7.48E + 03

[8]

9.78E + 03

[9]

2.58E + 03

[10]

3.36E + 03

[11]

1.06E + 03

[30] array · 12 items

[0]

XP_027246369.1

[1]

Proteasome activator complex subunit 2

[2]

26429.15

[3]

5.56

[4]

1.13E + 05

[5]

2.36E + 03

[6]

4.70E + 03

[7]

1.97E + 02

[8]

4.90E + 03

[9]

3.34E + 02

[10]

3.57E + 03

[11]

2.35E + 03

[31] array · 12 items

[0]

XP_027246859.1

[1]

N(4)-(beta-n-acetylglucosaminyl)-l-asparaginase

[2]

38261.44

[3]

7.12

[4]

1.23E + 06

[5]

9.43E + 03

[6]

1.15E + 04

[7]

1.37E + 03

[8]

6.19E + 03

[9]

1.30E + 03

[10]

1.29E + 04

[11]

3.62E + 03

[32] array · 12 items

[0]

XP_027246972.1

[1]

Acid ceramidase isoform x2

[2]

49761.99

[3]

8.82

[4]

1.50E + 06

[5]

8.16E + 03

[6]

1.59E + 04

[7]

5.97E + 03

[8]

8.56E + 03

[9]

6.78E + 03

[10]

6.29E + 03

[11]

4.22E + 02

[33] array · 12 items

[0]

XP_027247933.1

[1]

Matrix metalloproteinase-19

[2]

58055.66

[3]

7.71

[4]

2.96E + 05

[5]

4.19E + 03

[6]

1.28E + 04

[7]

4.63E + 03

[8]

3.88E + 03

[9]

5.13E + 02

[10]

5.59E + 03

[11]

3.10E + 03

[34] array · 12 items

[0]

XP_027247964.1

[1]

Proliferation-associated protein 2g4

[2]

43569.39

[3]

6.26

[4]

3.38E + 05

[5]

3.74E + 03

[6]

5.78E + 03

[7]

6.43E + 02

[8]

3.73E + 03

[9]

1.88E + 03

[10]

3.38E + 03

[11]

2.79E + 03

[35] array · 12 items

[0]

XP_027248157.1

[1]

T-complex protein 1 subunit beta

[2]

59161.48

[3]

6.01

[4]

2.12E + 05

[5]

5.79E + 03

[6]

1.05E + 04

[7]

2.92E + 03

[8]

4.84E + 03

[9]

2.46E + 03

[10]

5.70E + 03

[11]

3.22E + 03

[36] array · 12 items

[0]

XP_027248343.1

[1]

Endoplasmin

[2]

88686.92

[3]

4.75

[4]

1.27E + 06

[5]

1.25E + 04

[6]

1.99E + 04

[7]

9.46E + 03

[8]

5.93E + 03

[9]

2.39E + 02

[10]

5.95E + 03

[11]

3.77E + 03

[37] array · 12 items

[0]

XP_027248903.1

[1]

T-complex protein 1 subunit gamma

[2]

60267.3

[3]

6.23

[4]

3.02E + 05

[5]

4.03E + 03

[6]

4.27E + 03

[7]

1.29E + 03

[8]

3.08E + 04

[9]

2.08E + 04

[10]

3.22E + 03

[11]

4.42E + 02

[38] array · 12 items

[0]

XP_027249017.1

[1]

Thrombospondin-3 isoform x1

[2]

105716.58

[3]

4.4

[4]

2.32E + 04

[5]

1.44E + 03

[6]

3.39E + 03

[7]

1.95E + 03

[8]

7.44E + 03

[9]

1.00E + 03

[10]

3.86E + 03

[11]

4.02E + 03

[39] array · 12 items

[0]

XP_027249018.1

[1]

Thrombospondin-3 isoform x2

[2]

104721.34

[3]

4.4

[4]

1.79E + 05

[5]

7.72E + 03

[6]

7.11E + 03

[7]

5.20E + 03

[8]

8.59E + 03

[9]

4.08E + 03

[10]

1.81E + 04

[11]

1.98E + 04

[40] array · 12 items

[0]

XP_027249169.1

[1]

Protein s100-a6 isoform x1

[2]

9841.82

[3]

5.3

[4]

8.07E + 06

[5]

1.67E + 05

[6]

1.60E + 04

[7]

5.65E + 03

[8]

4.65E + 03

[9]

3.21E + 03

[10]

7.52E + 03

[11]

7.43E + 03

[41] array · 12 items

[0]

XP_027249297.1

[1]

Semaphorin-3e

[2]

85922.37

[3]

7.95

[4]

1.44E + 05

[5]

2.87E + 03

[6]

4.62E + 03

[7]

1.20E + 03

[8]

1.70E + 03

[9]

3.49E + 02

[10]

5.89E + 03

[11]

4.68E + 03

[42] array · 12 items

[0]

XP_027249460.1

[1]

Extracellular matrix protein 1 isoform x1

[2]

62257.78

[3]

6.36

[4]

1.72E + 04

[5]

5.79E + 02

[6]

1.28E + 03

[7]

1.40E + 02

[8]

2.50E + 03

[9]

2.60E + 03

[10]

6.91E + 02

[11]

2.97E + 02

[43] array · 12 items

[0]

XP_027249462.1

[1]

Extracellular matrix protein 1 isoform x3

[2]

60267.3

[3]

6.98

[4]

1.34E + 05

[5]

1.89E + 03

[6]

1.83E + 04

[7]

1.84E + 04

[8]

7.95E + 03

[9]

4.12E + 03

[10]

3.93E + 03

[11]

1.67E + 03

[44] array · 12 items

[0]

XP_027249711.1

[1]

Importin-5 isoform x2

[2]

118212.37

[3]

4.82

[4]

8.57E + 04

[5]

4.24E + 02

[6]

5.88E + 03

[7]

9.94E + 02

[8]

5.75E + 03

[9]

9.18E + 02

[10]

6.82E + 03

[11]

6.38E + 02

[45] array · 12 items

[0]

XP_027250030.1

[1]

Macrophage migration inhibitory factor

[2]

12716.95

[3]

6.8

[4]

8.91E + 04

[5]

4.48E + 03

[6]

1.40E + 03

[7]

1.11E + 03

[8]

6.31E + 03

[9]

1.85E + 03

[10]

5.03E + 03

[11]

3.27E + 03

[46] array · 12 items

[0]

XP_027251765.1

[1]

Glyceraldehyde-3-phosphate dehydrogenase

[2]

39367.26

[3]

6.67

[4]

3.67E + 04

[5]

5.91E + 02

[6]

2.07E + 03

[7]

1.31E + 03

[8]

1.19E + 03

[9]

2.51E + 02

[10]

2.12E + 03

[11]

9.94E + 02

[47] array · 12 items

[0]

XP_027251842.1

[1]

Keratin, type ii cytoskeletal 2 epidermal isoform x2

[2]

71767.85

[3]

6.46

[4]

1.50E + 06

[5]

9.43E + 03

[6]

6.13E + 03

[7]

9.39E + 02

[8]

3.48E + 03

[9]

3.28E + 03

[10]

7.69E + 03

[11]

3.48E + 03

[48] array · 12 items

[0]

XP_027252444.1

[1]

Keratin, type ii cytoskeletal 1b isoform x2

[2]

65243.5

[3]

8.51

[4]

1.04E + 06

[5]

1.63E + 04

[6]

1.28E + 03

[7]

1.46E + 03

[8]

4.72E + 02

[9]

5.08E + 02

[10]

1.58E + 03

[11]

1.56E + 03

[49] array · 12 items

[0]

XP_027252959.1

[1]

Fibronectin isoform x3

[2]

264291.46

[3]

5.57

[4]

3.89E + 04

[5]

7.41E + 02

[6]

1.21E + 03

[7]

3.47E + 02

[8]

7.93E + 02

[9]

4.26E + 02

[10]

2.39E + 04

[11]

3.24E + 04

[50] array · 12 items

[0]

XP_027252960.1

[1]

Fibronectin isoform x4

[2]

264180.88

[3]

5.58

[4]

1.52E + 05

[5]

1.08E + 04

[6]

7.22E + 03

[7]

3.35E + 03

[8]

2.28E + 04

[9]

7.94E + 03

[10]

1.34E + 04

[11]

7.40E + 03

[51] array · 12 items

[0]

XP_027252964.1

[1]

Fibronectin isoform x8

[2]

254228.48

[3]

5.77

[4]

8.16E + 04

[5]

3.45E + 03

[6]

6.85E + 03

[7]

1.04E + 03

[8]

3.82E + 03

[9]

1.30E + 03

[10]

2.41E + 03

[11]

7.61E + 02

[52] array · 12 items

[0]

XP_027252965.1

[1]

Fibronectin isoform x9

[2]

251463.92

[3]

5.83

[4]

2.30E + 05

[5]

5.19E + 03

[6]

3.07E + 03

[7]

7.38E + 02

[8]

5.71E + 03

[9]

2.44E + 03

[10]

4.73E + 03

[11]

1.71E + 03

[53] array · 12 items

[0]

XP_027252966.1

[1]

Fibronectin isoform x10

[2]

251021.59

[3]

5.57

[4]

6.16E + 04

[5]

2.45E + 03

[6]

3.39E + 03

[7]

1.18E + 03

[8]

3.09E + 03

[9]

1.74E + 03

[10]

2.11E + 03

[11]

2.59E + 02

[54] array · 12 items

[0]

XP_027252967.1

[1]

Fibronectin isoform x11

[2]

250911.01

[3]

5.59

[4]

1.53E + 05

[5]

1.89E + 03

[6]

4.97E + 03

[7]

2.78E + 03

[8]

9.17E + 03

[9]

2.75E + 03

[10]

9.79E + 03

[11]

6.14E + 03

[55] array · 12 items

[0]

XP_027252968.1

[1]

Fibronectin isoform x12

[2]

240958.61

[3]

5.8

[4]

1.54E + 05

[5]

4.50E + 03

[6]

1.46E + 04

[7]

1.30E + 04

[8]

2.95E + 03

[9]

1.30E + 03

[10]

6.90E + 03

[11]

7.39E + 02

[56] array · 12 items

[0]

XP_027254100.1

[1]

Alpha-enolase isoform x2

[2]

47992.67

[3]

[4]

4.97E + 05

[5]

1.13E + 04

[6]

3.68E + 03

[7]

1.84E + 03

[8]

1.32E + 04

[9]

2.97E + 03

[10]

6.68E + 03

[11]

2.77E + 03

[57] array · 12 items

[0]

XP_027255561.1

[1]

Basement membrane-specific heparan sulfate proteoglycan core protein isoform x2

[2]

485013.53

[3]

6.12

[4]

7.95E + 05

[5]

1.04E + 04

[6]

3.00E + 03

[7]

2.41E + 02

[8]

2.78E + 03

[9]

3.88E + 02

[10]

2.47E + 03

[11]

1.50E + 02

[58] array · 12 items

[0]

XP_027255877.1

[1]

T-complex protein 1 subunit epsilon

[2]

59824.97

[3]

5.34

[4]

3.69E + 05

[5]

3.68E + 03

[6]

3.49E + 03

[7]

2.88E + 03

[8]

1.57E + 04

[9]

1.21E + 04

[10]

9.98E + 03

[11]

7.76E + 03

[59] array · 12 items

[0]

XP_027256703.1

[1]

Peptidyl-prolyl cis-trans isomerase c isoform x2

[2]

23443.43

[3]

7.77

[4]

6.34E + 05

[5]

1.01E + 04

[6]

6.93E + 03

[7]

2.65E + 03

[8]

2.64E + 03

[9]

1.03E + 03

[10]

6.95E + 03

[11]

4.44E + 03

[60] array · 12 items

[0]

XP_027259082.1

[1]

Transitional endoplasmic reticulum atpase isoform x2

[2]

89129.25

[3]

5.14

[4]

1.47E + 05

[5]

5.44E + 03

[6]

3.57E + 03

[7]

3.16E + 02

[8]

1.49E + 03

[9]

4.15E + 02

[10]

3.68E + 03

[11]

1.89E + 03

[61] array · 12 items

[0]

XP_027259718.1

[1]

Myosin-9 isoform x2

[2]

216741.11

[3]

5.53

[4]

1.07E + 05

[5]

2.87E + 03

[6]

7.70E + 03

[7]

3.08E + 03

[8]

1.05E + 04

[9]

2.62E + 03

[10]

1.45E + 04

[11]

8.49E + 03

[62] array · 12 items

[0]

XP_027259782.1

[1]

Eukaryotic translation initiation factor 3 subunit l

[2]

62368.36

[3]

5.93

[4]

8.15E + 04

[5]

3.27E + 03

[6]

1.89E + 03

[7]

4.26E + 02

[8]

3.65E + 03

[9]

3.71E + 03

[10]

1.04E + 03

[11]

4.07E + 02

[63] array · 12 items

[0]

XP_027260200.1

[1]

Serine protease htra1 isoform x2

[2]

53079.46

[3]

8.07

[4]

3.94E + 05

[5]

3.74E + 03

[6]

8.62E + 03

[7]

2.82E + 03

[8]

5.98E + 03

[9]

1.59E + 03

[10]

1.10E + 04

[11]

1.50E + 03

[64] array · 12 items

[0]

XP_027260201.1

[1]

Serine protease htra1 isoform x3

[2]

51863.05

[3]

8.07

[4]

1.01E + 06

[5]

1.28E + 04

[6]

1.24E + 04

[7]

9.94E + 03

[8]

7.87E + 03

[9]

1.46E + 03

[10]

6.79E + 03

[11]

3.04E + 03

[65] array · 12 items

[0]

XP_027260557.1

[1]

Lysosome-associated membrane glycoprotein 1

[2]

44564.63

[3]

6.31

[4]

4.37E + 04

[5]

5.38E + 03

[6]

1.38E + 03

[7]

9.38E + 02

[8]

7.66E + 02

[9]

4.51E + 02

[10]

1.87E + 03

[11]

2.03E + 03

[66] array · 12 items

[0]

XP_027260936.1

[1]

Inter-alpha-trypsin inhibitor heavy chain h5 isoform x2

[2]

105274.25

[3]

8.44

[4]

2.58E + 05

[5]

4.55E + 03

[6]

8.44E + 03

[7]

3.31E + 03

[8]

1.21E + 04

[9]

1.76E + 03

[10]

1.03E + 04

[11]

5.14E + 03

[67] array · 12 items

[0]

XP_027261047.1

[1]

Vimentin

[2]

51531.31

[3]

5.06

[4]

6.48E + 05

[5]

8.99E + 03

[6]

6.89E + 03

[7]

1.49E + 03

[8]

6.15E + 03

[9]

1.20E + 03

[10]

1.08E + 04

[11]

1.92E + 03

[68] array · 12 items

[0]

XP_027263120.1

[1]

Phosphoglycerate mutase 1 isoform x2

[2]

28087.88

[3]

6.67

[4]

4.00E + 05

[5]

1.14E + 04

[6]

3.20E + 03

[7]

5.68E + 02

[8]

2.80E + 03

[9]

1.33E + 03

[10]

3.80E + 03

[11]

2.32E + 03

[69] array · 12 items

[0]

XP_027263985.1

[1]

Lactadherin isoform x5

[2]

54185.28

[3]

8.13

[4]

7.15E + 04

[5]

1.60E + 03

[6]

3.87E + 04

[7]

2.55E + 04

[8]

8.11E + 03

[9]

4.41E + 03

[10]

1.00E + 04

[11]

2.25E + 03

[70] array · 12 items

[0]

XP_027263987.1

[1]

Lactadherin isoform x7

[2]

47218.6

[3]

8.15

[4]

7.42E + 04

[5]

3.09E + 03

[6]

4.13E + 04

[7]

2.40E + 04

[8]

2.71E + 04

[9]

8.87E + 03

[10]

7.45E + 03

[11]

2.58E + 03

[71] array · 12 items

[0]

XP_027264128.1

[1]

Elongation factor 1-gamma

[2]

48324.42

[3]

6.36

[4]

4.77E + 05

[5]

1.67E + 04

[6]

1.37E + 04

[7]

6.62E + 03

[8]

6.75E + 04

[9]

2.97E + 04

[10]

1.07E + 04

[11]

5.08E + 03

[72] array · 12 items

[0]

XP_027264138.1

[1]

Neutral alpha-glucosidase ab isoform x1

[2]

106822.41

[3]

5.72

[4]

9.50E + 04

[5]

3.31E + 03

[6]

1.14E + 03

[7]

4.22E + 02

[8]

8.78E + 02

[9]

3.61E + 02

[10]

8.97E + 02

[11]

3.95E + 02

[73] array · 12 items

[0]

XP_027264139.1

[1]

Neutral alpha-glucosidase ab isoform x2

[2]

104389.6

[3]

5.64

[4]

1.13E + 05

[5]

2.05E + 03

[6]

2.83E + 03

[7]

1.63E + 03

[8]

2.97E + 03

[9]

5.28E + 02

[10]

3.32E + 03

[11]

7.89E + 02

[74] array · 12 items

[0]

XP_027264402.1

[1]

Cofilin-1

[2]

18356.65

[3]

8.22

[4]

1.77E + 05

[5]

2.49E + 03

[6]

1.63E + 04

[7]

2.38E + 03

[8]

7.33E + 03

[9]

3.25E + 03

[10]

7.15E + 03

[11]

1.52E + 03

[75] array · 12 items

[0]

XP_027264538.1

[1]

Glutathione s-transferase p 2 isoform x2

[2]

24549.25

[3]

9.15

[4]

6.72E + 05

[5]

1.45E + 04

[6]

5.93E + 03

[7]

2.07E + 03

[8]

3.97E + 03

[9]

7.10E + 02

[10]

6.04E + 03

[11]

6.45E + 02

[76] array · 12 items

[0]

XP_027264700.1

[1]

Cathepsin d

[2]

45117.54

[3]

6.54

[4]

3.14E + 06

[5]

8.52E + 04

[6]

4.20E + 03

[7]

1.77E + 03

[8]

3.69E + 03

[9]

2.46E + 02

[10]

7.13E + 03

[11]

8.45E + 02

[77] array · 12 items

[0]

XP_027265239.1

[1]

Nidogen-1 isoform x3

[2]

137785.42

[3]

5.07

[4]

2.26E + 05

[5]

2.16E + 03

[6]

8.47E + 03

[7]

4.13E + 03

[8]

8.31E + 03

[9]

1.15E + 03

[10]

1.26E + 04

[11]

9.76E + 03

[78] array · 12 items

[0]

XP_027265604.1

[1]

Vesicular integral-membrane protein vip36

[2]

39367.26

[3]

6.46

[4]

3.50E + 05

[5]

4.55E + 03

[6]

4.76E + 03

[7]

1.73E + 03

[8]

2.83E + 03

[9]

2.49E + 02

[10]

4.31E + 03

[11]

3.65E + 03

[79] array · 12 items

[0]

XP_027265952.1

[1]

Nucleobindin-2 isoform x1

[2]

47660.93

[3]

4.97

[4]

7.63E + 04

[5]

2.52E + 03

[6]

1.71E + 03

[7]

6.58E + 02

[8]

4.59E + 03

[9]

3.33E + 03

[10]

2.87E + 03

[11]

6.01E + 02

[80] array · 12 items

[0]

XP_027265953.1

[1]

Nucleobindin-2 isoform x2

[2]

46444.52

[3]

5.05

[4]

1.04E + 06

[5]

2.76E + 04

[6]

5.90E + 03

[7]

4.83E + 02

[8]

2.61E + 03

[9]

8.63E + 02

[10]

9.13E + 03

[11]

2.25E + 03

[81] array · 12 items

[0]

XP_027267107.1

[1]

Peptidyl-prolyl cis-trans isomerase b

[2]

23885.76

[3]

9.59

[4]

1.60E + 06

[5]

4.71E + 03

[6]

3.04E + 03

[7]

3.90E + 02

[8]

3.38E + 03

[9]

2.36E + 02

[10]

4.35E + 03

[11]

1.07E + 03

[82] array · 12 items

[0]

XP_027267400.1

[1]

Glucosidase 2 subunit beta isoform x2

[2]

58055.66

[3]

4.41

[4]

5.89E + 05

[5]

6.68E + 03

[6]

5.13E + 03

[7]

1.24E + 03

[8]

6.16E + 03

[9]

2.30E + 03

[10]

4.47E + 03

[11]

6.21E + 02

[83] array · 12 items

[0]

XP_027267710.1

[1]

Complement c1q tumor necrosis factor-related protein 5 isoform x3

[2]

26871.47

[3]

5.94

[4]

1.02E + 06

[5]

3.98E + 04

[6]

3.60E + 03

[7]

2.52E + 03

[8]

3.18E + 03

[9]

1.11E + 03

[10]

3.28E + 03

[11]

9.85E + 02

[84] array · 12 items

[0]

XP_027267915.1

[1]

Neural cell adhesion molecule 1 isoform x4

[2]

123852.06

[3]

4.71

[4]

5.10E + 05

[5]

4.32E + 03

[6]

8.72E + 03

[7]

3.14E + 03

[8]

4.99E + 03

[9]

2.91E + 03

[10]

7.09E + 03

[11]

2.69E + 02

[85] array · 12 items

[0]

XP_027267916.1

[1]

Neural cell adhesion molecule 1 isoform x5

[2]

93994.87

[3]

4.8

[4]

5.32E + 04

[5]

1.45E + 03

[6]

1.36E + 03

[7]

5.10E + 02

[8]

8.44E + 02

[9]

9.77E + 01

[10]

2.43E + 03

[11]

3.37E + 02

[86] array · 12 items

[0]

XP_027267917.1

[1]

Neural cell adhesion molecule 1 isoform x6

[2]

93884.29

[3]

4.79

[4]

2.57E + 05

[5]

8.73E + 03

[6]

3.11E + 03

[7]

3.85E + 02

[8]

1.78E + 03

[9]

8.40E + 02

[10]

8.69E + 03

[11]

2.27E + 03

[87] array · 12 items

[0]

XP_027267919.1

[1]

Neural cell adhesion molecule 1 isoform x8

[2]

93773.71

[3]

4.8

[4]

1.11E + 05

[5]

3.30E + 03

[6]

5.21E + 03

[7]

3.36E + 03

[8]

2.83E + 03

[9]

3.41E + 03

[10]

1.36E + 03

[11]

2.69E + 02

[88] array · 12 items

[0]

XP_027267920.1

[1]

Neural cell adhesion molecule 1 isoform x9

[2]

80393.26

[3]

4.77

[4]

2.91E + 05

[5]

2.45E + 03

[6]

8.57E + 03

[7]

3.57E + 03

[8]

2.03E + 03

[9]

1.79E + 02

[10]

5.70E + 03

[11]

1.60E + 03

[89] array · 12 items

[0]

XP_027267921.1

[1]

Neural cell adhesion molecule 1 isoform x10

[2]

80282.68

[3]

4.79

[4]

1.15E + 05

[5]

2.05E + 03

[6]

9.81E + 03

[7]

1.40E + 03

[8]

3.19E + 03

[9]

1.23E + 03

[10]

3.04E + 03

[11]

3.02E + 02

[90] array · 12 items

[0]

XP_027268152.1

[1]

T-complex protein 1 subunit theta isoform x2

[2]

60599.05

[3]

5.43

[4]

3.22E + 05

[5]

4.71E + 02

[6]

3.87E + 03

[7]

1.01E + 03

[8]

1.34E + 04

[9]

3.84E + 03

[10]

9.09E + 03

[11]

5.29E + 03

[91] array · 12 items

[0]

XP_027268153.1

[1]

T-complex protein 1 subunit theta isoform x3

[2]

54959.35

[3]

5.19

[4]

2.89E + 05

[5]

4.50E + 03

[6]

4.77E + 03

[7]

2.10E + 03

[8]

1.82E + 03

[9]

2.87E + 01

[10]

1.98E + 03

[11]

8.82E + 02

[92] array · 12 items

[0]

XP_027269607.1

[1]

Beta-glucuronidase isoform x4

[2]

72431.34

[3]

6.28

[4]

1.78E + 05

[5]

5.72E + 03

[6]

4.30E + 03

[7]

3.84E + 03

[8]

2.62E + 03

[9]

6.07E + 02

[10]

1.72E + 03

[11]

1.38E + 02

[93] array · 12 items

[0]

XP_027269616.1

[1]

T-complex protein 1 subunit zeta

[2]

58719.15

[3]

6.46

[4]

1.72E + 05

[5]

3.09E + 03

[6]

6.45E + 03

[7]

1.93E + 03

[8]

2.54E + 03

[9]

1.32E + 03

[10]

5.12E + 03

[11]

4.02E + 03

[94] array · 12 items

[0]

XP_027269644.1

[1]

Gtp-binding nuclear protein ran isoform x2

[2]

23885.76

[3]

7.01

[4]

5.37E + 05

[5]

1.03E + 04

[6]

6.36E + 03

[7]

2.76E + 03

[8]

7.70E + 03

[9]

4.69E + 03

[10]

6.51E + 03

[11]

3.57E + 03

[95] array · 12 items

[0]

XP_027269956.1

[1]

Phospholipase b-like 2

[2]

64690.59

[3]

5.9

[4]

1.10E + 06

[5]

4.78E + 04

[6]

3.95E + 04

[7]

4.71E + 04

[8]

1.53E + 04

[9]

1.01E + 04

[10]

7.36E + 03

[11]

1.74E + 03

[96] array · 12 items

[0]

XP_027270355.1

[1]

Transforming protein rhoa

[2]

21342.36

[3]

5.83

[4]

1.56E + 05

[5]

1.25E + 03

[6]

2.82E + 03

[7]

4.60E + 02

[8]

2.38E + 03

[9]

5.30E + 02

[10]

3.50E + 03

[11]

1.43E + 03

[97] array · 12 items

[0]

XP_027270673.1

[1]

Pyruvate kinase pkm isoform x1

[2]

58719.15

[3]

6.69

[4]

8.65E + 05

[5]

1.64E + 04

[6]

1.27E + 04

[7]

7.34E + 03

[8]

2.17E + 03

[9]

6.46E + 02

[10]

4.50E + 03

[11]

2.64E + 03

[98] array · 12 items

[0]

XP_027270674.1

[1]

Pyruvate kinase pkm isoform x2

[2]

58719.15

[3]

6.88

[4]

1.09E + 06

[5]

2.36E + 04

[6]

8.46E + 03

[7]

3.88E + 03

[8]

6.72E + 03

[9]

3.48E + 03

[10]

5.74E + 03

[11]

2.39E + 03

[99] array · 12 items

[0]

XP_027270675.1

[1]

Pyruvate kinase pkm isoform x3

[2]

57060.42

[3]

8.65

[4]

8.09E + 05

[5]

2.66E + 04

[6]

1.53E + 04

[7]

5.98E + 03

[8]

4.50E + 03

[9]

3.28E + 03

[10]

8.36E + 03

[11]

2.70E + 03

[100] array · 12 items

[0]

XP_027270716.1

[1]

Lysyl oxidase homolog 1 isoform x2

[2]

67012.81

[3]

6.57

[4]

1.94E + 05

[5]

4.71E + 02

[6]

7.19E + 03

[7]

3.63E + 03

[8]

8.20E + 03

[9]

2.73E + 03

[10]

7.55E + 03

[11]

1.64E + 03

[101] array · 12 items

[0]

XP_027270812.1

[1]

Chondroitin sulfate proteoglycan 4

[2]

256882.45

[3]

5.41

[4]

2.63E + 05

[5]

5.72E + 03

[6]

1.03E + 04

[7]

9.31E + 03

[8]

1.06E + 04

[9]

4.45E + 03

[10]

1.45E + 04

[11]

6.25E + 03

[102] array · 12 items

[0]

XP_027271096.1

[1]

Beta-galactosidase isoform x3

[2]

75859.39

[3]

8.58

[4]

4.32E + 04

[5]

2.36E + 03

[6]

1.06E + 03

[7]

1.24E + 02

[8]

1.81E + 03

[9]

7.72E + 02

[10]

9.83E + 03

[11]

2.59E + 03

[103] array · 12 items

[0]

XP_027271097.1

[1]

Beta-galactosidase isoform x4

[2]

73868.91

[3]

6.71

[4]

3.52E + 05

[5]

7.41E + 03

[6]

4.27E + 03

[7]

5.47E + 02

[8]

4.18E + 03

[9]

1.49E + 03

[10]

5.98E + 03

[11]

2.17E + 03

[104] array · 12 items

[0]

XP_027271619.1

[1]

Elongation factor 1-alpha 1

[2]

50646.65

[3]

7.9

[4]

8.78E + 05

[5]

4.10E + 04

[6]

1.19E + 02

[7]

8.16E + 01

[8]

5.76E + 01

[9]

5.97E + 01

[10]

1.89E + 02

[11]

1.39E + 02

[105] array · 12 items

[0]

XP_027271991.1

[1]

Malate dehydrogenase, mitochondrial isoform x2

[2]

37376.78

[3]

8.93

[4]

1.35E + 05

[5]

4.03E + 03

[6]

3.97E + 03

[7]

1.35E + 03

[8]

3.21E + 03

[9]

8.13E + 02

[10]

3.77E + 03

[11]

8.51E + 02

[106] array · 12 items

[0]

XP_027272021.1

[1]

Plasminogen activator inhibitor 1 isoform x2

[2]

44454.04

[3]

7.2

[4]

4.74E + 06

[5]

1.02E + 05

[6]

7.43E + 03

[7]

2.19E + 03

[8]

7.02E + 03

[9]

2.94E + 03

[10]

9.84E + 03

[11]

5.02E + 03

[107] array · 12 items

[0]

XP_027272044.1

[1]

Procollagen c-endopeptidase enhancer 1

[2]

51752.47

[3]

8.16

[4]

2.76E + 05

[5]

7.59E + 03

[6]

7.26E + 03

[7]

3.63E + 03

[8]

5.78E + 03

[9]

1.27E + 03

[10]

5.10E + 03

[11]

3.45E + 02

[108] array · 12 items

[0]

XP_027272591.1

[1]

Complement c3

[2]

184229.95

[3]

6.2

[4]

6.09E + 04

[5]

2.70E + 03

[6]

5.08E + 03

[7]

1.33E + 03

[8]

1.07E + 04

[9]

3.60E + 03

[10]

5.28E + 03

[11]

1.91E + 03

[109] array · 12 items

[0]

XP_027272776.1

[1]

Laminin subunit beta-1 isoform x5

[2]

197499.81

[3]

4.78

[4]

2.42E + 05

[5]

4.71E + 02

[6]

6.80E + 03

[7]

3.52E + 03

[8]

1.80E + 03

[9]

5.07E + 02

[10]

1.12E + 04

[11]

5.03E + 03

[110] array · 12 items

[0]

XP_027272779.1

[1]

Laminin subunit beta-1 isoform x3

[2]

186662.75

[3]

4.76

[4]

1.91E + 05

[5]

5.44E + 03

[6]

3.96E + 03

[7]

4.81E + 02

[8]

3.41E + 03

[9]

1.03E + 03

[10]

6.88E + 03

[11]

2.99E + 03

[111] array · 12 items

[0]

XP_027272780.1

[1]

Laminin subunit beta-1 isoform x4

[2]

162666.42

[3]

4.7

[4]

6.79E + 04

[5]

1.57E + 03

[6]

1.64E + 03

[7]

9.69E + 02

[8]

2.11E + 03

[9]

9.24E + 02

[10]

4.12E + 03

[11]

5.00E + 02

[112] array · 12 items

[0]

XP_027273163.1

[1]

Laminin subunit gamma-1 isoform x2

[2]

177705.6

[3]

4.99

[4]

1.16E + 05

[5]

3.86E + 03

[6]

9.84E + 03

[7]

9.17E + 03

[8]

4.12E + 03

[9]

1.37E + 03

[10]

4.26E + 03

[11]

3.94E + 02

[113] array · 12 items

[0]

XP_027274751.1

[1]

Immunoglobulin superfamily member 8 isoform x3

[2]

66902.23

[3]

7.94

[4]

7.24E + 04

[5]

1.28E + 03

[6]

2.32E + 03

[7]

6.47E + 02

[8]

6.75E + 03

[9]

4.73E + 03

[10]

3.08E + 03

[11]

5.51E + 02

[114] array · 12 items

[0]

XP_027274961.1

[1]

Legumain

[2]

48435

[3]

6.07

[4]

3.01E + 06

[5]

3.40E + 04

[6]

6.31E + 03

[7]

1.19E + 03

[8]

5.76E + 03

[9]

2.85E + 03

[10]

6.16E + 03

[11]

4.75E + 03

[115] array · 12 items

[0]

XP_027275654.1

[1]

Cathepsin z

[2]

33838.15

[3]

7.52

[4]

3.29E + 06

[5]

4.64E + 04

[6]

1.44E + 04

[7]

6.08E + 03

[8]

8.88E + 03

[9]

5.11E + 03

[10]

5.29E + 03

[11]

1.74E + 03

[116] array · 12 items

[0]

XP_027275687.1

[1]

Laminin subunit alpha-5

[2]

413024.52

[3]

6.49

[4]

8.50E + 04

[5]

1.33E + 03

[6]

8.53E + 03

[7]

2.29E + 03

[8]

5.54E + 03

[9]

3.87E + 03

[10]

4.65E + 03

[11]

1.58E + 03

[117] array · 12 items

[0]

XP_027276427.1

[1]

Nucleobindin-1 isoform x3

[2]

50536.07

[3]

5.14

[4]

7.26E + 05

[5]

8.60E + 03

[6]

2.58E + 03

[7]

9.22E + 02

[8]

5.52E + 03

[9]

2.30E + 03

[10]

1.06E + 04

[11]

6.58E + 03

[118] array · 12 items

[0]

XP_027277053.1

[1]

Protein-glutamine gamma-glutamyltransferase 2

[2]

75859.39

[3]

5.08

[4]

1.08E + 05

[5]

3.30E + 03

[6]

1.76E + 03

[7]

7.39E + 02

[8]

1.03E + 03

[9]

6.81E + 02

[10]

4.04E + 03

[11]

2.16E + 03

[119] array · 12 items

[0]

XP_027278026.1

[1]

Thrombospondin-1 isoform x2

[2]

129381.17

[3]

4.7

[4]

1.12E + 06

[5]

2.36E + 04

[6]

9.32E + 03

[7]

3.97E + 03

[8]

6.71E + 03

[9]

9.85E + 02

[10]

7.11E + 03

[11]

1.68E + 03

[120] array · 12 items

[0]

XP_027278163.1

[1]

Catalase isoform x1

[2]

61373.12

[3]

8.29

[4]

7.38E + 04

[5]

3.74E + 03

[6]

2.23E + 03

[7]

7.48E + 02

[8]

2.00E + 03

[9]

1.10E + 03

[10]

7.40E + 03

[11]

1.58E + 03

[121] array · 12 items

[0]

XP_027278164.1

[1]

Catalase isoform x2

[2]

53742.95

[3]

7.33

[4]

7.48E + 04

[5]

1.10E + 03

[6]

2.48E + 03

[7]

2.46E + 02

[8]

2.36E + 03

[9]

6.59E + 02

[10]

7.45E + 03

[11]

8.38E + 02

[122] array · 12 items

[0]

XP_027279237.1

[1]

Matrix metalloproteinase-9

[2]

78513.36

[3]

5.6

[4]

4.31E + 04

[5]

2.60E + 03

[6]

4.31E + 03

[7]

1.59E + 03

[8]

1.05E + 04

[9]

3.66E + 03

[10]

5.71E + 03

[11]

2.24E + 03

[123] array · 12 items

[0]

XP_027279240.1

[1]

Lysosomal protective protein

[2]

54517.02

[3]

5.64

[4]

1.34E + 06

[5]

0.00E + 00

[6]

3.44E + 03

[7]

1.21E + 03

[8]

6.16E + 03

[9]

1.66E + 03

[10]

4.86E + 03

[11]

3.13E + 03

[124] array · 12 items

[0]

XP_027279242.1

[1]

Phospholipid transfer protein isoform x2

[2]

49761.99

[3]

5.94

[4]

3.95E + 05

[5]

2.05E + 03

[6]

7.01E + 03

[7]

1.74E + 03

[8]

2.75E + 03

[9]

1.23E + 03

[10]

5.27E + 03

[11]

1.83E + 03

[125] array · 12 items

[0]

XP_027279907.1

[1]

Insulin-like growth factor-binding protein 4

[2]

28087.88

[3]

6.78

[4]

2.80E + 05

[5]

4.71E + 03

[6]

2.10E + 03

[7]

1.78E + 03

[8]

4.60E + 02

[9]

1.44E + 02

[10]

4.72E + 02

[11]

7.07E + 01

[126] array · 12 items

[0]

XP_027280118.1

[1]

Nucleoside diphosphate kinase b

[2]

16808.49

[3]

7.78

[4]

8.71E + 05

[5]

8.65E + 03

[6]

2.13E + 03

[7]

4.30E + 02

[8]

5.08E + 03

[9]

3.38E + 03

[10]

3.93E + 03

[11]

7.21E + 02

[127] array · 12 items

[0]

XP_027280121.1

[1]

Nucleoside diphosphate kinase a isoform x1

[2]

16808.49

[3]

5.96

[4]

4.03E + 05

[5]

1.02E + 04

[6]

1.60E + 04

[7]

7.06E + 03

[8]

2.90E + 04

[9]

1.91E + 04

[10]

1.83E + 04

[11]

2.18E + 04

[128] array · 12 items

[0]

XP_027280122.1

[1]

Nucleoside diphosphate kinase a isoform x2

[2]

12274.62

[3]

[4]

7.94E + 05

[5]

4.24E + 03

[6]

9.15E + 03

[7]

1.12E + 03

[8]

5.37E + 03

[9]

7.92E + 02

[10]

5.05E + 03

[11]

1.53E + 03

[129] array · 12 items

[0]

XP_027280299.1

[1]

Emilin-1 isoform x1

[2]

112462.1

[3]

5.24

[4]

1.37E + 05

[5]

6.18E + 03

[6]

2.13E + 03

[7]

6.39E + 02

[8]

3.16E + 03

[9]

5.94E + 02

[10]

9.26E + 03

[11]

2.71E + 03

[130] array · 12 items

[0]

XP_027280300.1

[1]

Emilin-1 isoform x2

[2]

101625.04

[3]

5.09

[4]

1.22E + 05

[5]

1.25E + 03

[6]

5.39E + 03

[7]

8.94E + 02

[8]

2.52E + 03

[9]

6.40E + 02

[10]

3.39E + 03

[11]

2.41E + 03

[131] array · 12 items

[0]

XP_027281003.1

[1]

Nucleophosmin isoform x2

[2]

32290

[3]

4.61

[4]

9.43E + 05

[5]

1.05E + 04

[6]

9.38E + 03

[7]

7.51E + 03

[8]

4.03E + 03

[9]

1.60E + 03

[10]

5.94E + 03

[11]

2.13E + 03

[132] array · 12 items

[0]

XP_027281136.1

[1]

Fatty acid synthase isoform x2

[2]

276787.25

[3]

5.95

[4]

9.64E + 04

[5]

2.36E + 03

[6]

7.46E + 03

[7]

6.20E + 03

[8]

7.63E + 03

[9]

9.34E + 02

[10]

6.81E + 03

[11]

3.24E + 03

[133] array · 12 items

[0]

XP_027281297.1

[1]

Lysosomal alpha-glucosidase

[2]

104942.51

[3]

5.65

[4]

6.10E + 05

[5]

2.82E + 04

[6]

1.64E + 04

[7]

9.02E + 03

[8]

1.80E + 04

[9]

2.88E + 03

[10]

4.56E + 03

[11]

1.55E + 03

[134] array · 12 items

[0]

XP_027281318.1

[1]

Galectin-3-binding protein

[2]

63474.18

[3]

5.06

[4]

9.51E + 05

[5]

2.46E + 04

[6]

1.26E + 04

[7]

5.04E + 03

[8]

8.36E + 03

[9]

5.68E + 03

[10]

6.46E + 03

[11]

3.00E + 03

[135] array · 12 items

[0]

XP_027281357.1

[1]

Septin-9 isoform x4

[2]

65464.66

[3]

7.16

[4]

7.81E + 04

[5]

9.63E + 02

[6]

1.28E + 04

[7]

3.83E + 03

[8]

3.51E + 03

[9]

2.62E + 03

[10]

3.64E + 03

[11]

1.17E + 03

[136] array · 12 items

[0]

XP_027281359.1

[1]

Septin-9 isoform x5

[2]

37045.04

[3]

7.1

[4]

7.81E + 04

[5]

3.14E + 03

[6]

8.26E + 02

[7]

3.54E + 02

[8]

4.29E + 02

[9]

1.56E + 02

[10]

6.13E + 02

[11]

3.17E + 02

[137] array · 12 items

[0]

XP_027282087.1

[1]

Retinoid-inducible serine carboxypeptidase

[2]

50314.9

[3]

5.39

[4]

4.82E + 05

[5]

1.41E + 03

[6]

3.12E + 03

[7]

1.43E + 03

[8]

2.39E + 03

[9]

1.85E + 03

[10]

2.59E + 03

[11]

9.03E + 02

[138] array · 12 items

[0]

XP_027282154.1

[1]

Clathrin heavy chain 1 isoform x3

[2]

185225.19

[3]

5.48

[4]

1.29E + 05

[5]

3.56E + 03

[6]

3.61E + 04

[7]

3.82E + 04

[8]

6.45E + 03

[9]

2.07E + 03

[10]

2.04E + 03

[11]

7.87E + 02

[139] array · 12 items

[0]

XP_027282301.1

[1]

C-c motif chemokine 2

[2]

15813.25

[3]

9.32

[4]

3.12E + 06

[5]

2.16E + 04

[6]

2.03E + 03

[7]

4.27E + 02

[8]

1.22E + 03

[9]

3.98E + 02

[10]

4.94E + 03

[11]

2.68E + 03

[140] array · 12 items

[0]

XP_027282549.1

[1]

Pigment epithelium-derived factor isoform x2

[2]

46223.36

[3]

6.43

[4]

3.52E + 05

[5]

3.74E + 03

[6]

7.57E + 03

[7]

4.32E + 03

[8]

4.18E + 03

[9]

1.21E + 03

[10]

1.60E + 04

[11]

1.49E + 04

[141] array · 12 items

[0]

XP_027282819.1

[1]

Eukaryotic initiation factor 4a-i

[2]

44896.37

[3]

5.32

[4]

1.30E + 05

[5]

6.13E + 03

[6]

4.71E + 03

[7]

1.77E + 03

[8]

4.04E + 03

[9]

1.25E + 03

[10]

5.36E + 03

[11]

1.55E + 03

[142] array · 12 items

[0]

XP_027283255.1

[1]

Sparc isoform x4

[2]

33838.15

[3]

4.75

[4]

1.27E + 05

[5]

4.71E + 02

[6]

2.26E + 03

[7]

1.06E + 03

[8]

3.57E + 03

[9]

8.75E + 02

[10]

4.94E + 03

[11]

9.27E + 02

[143] array · 12 items

[0]

XP_027283783.1

[1]

Granulins isoform x2

[2]

65464.66

[3]

5.97

[4]

1.15E + 06

[5]

2.05E + 04

[6]

4.31E + 03

[7]

3.70E + 03

[8]

3.09E + 03

[9]

5.03E + 02

[10]

2.42E + 03

[11]

3.59E + 02

[144] array · 12 items

[0]

XP_027284007.1

[1]

Keratin, type i cytoskeletal 10 isoform x3

[2]

62700.11

[3]

5.04

[4]

1.14E + 06

[5]

3.30E + 04

[6]

1.34E + 04

[7]

6.51E + 03

[8]

1.34E + 04

[9]

9.83E + 03

[10]

6.90E + 03

[11]

7.36E + 02

[145] array · 12 items

[0]

XP_027284023.1

[1]

Complement c1r subcomponent

[2]

77960.45

[3]

5.71

[4]

4.54E + 05

[5]

1.17E + 04

[6]

1.28E + 04

[7]

2.44E + 03

[8]

9.64E + 03

[9]

2.48E + 03

[10]

7.56E + 03

[11]

9.74E + 02

[146] array · 12 items

[0]

XP_027284024.1

[1]

Complement c1r subcomponent-like protein

[2]

53742.95

[3]

6.31

[4]

1.27E + 05

[5]

4.03E + 03

[6]

1.73E + 04

[7]

2.46E + 03

[8]

1.04E + 04

[9]

1.90E + 03

[10]

7.97E + 03

[11]

2.96E + 03

[147] array · 12 items

[0]

XP_027284060.1

[1]

Triosephosphate isomerase isoform x2

[2]

27534.97

[3]

6.13

[4]

3.21E + 05

[5]

4.50E + 03

[6]

2.85E + 03

[7]

1.18E + 03

[8]

7.05E + 03

[9]

5.43E + 02

[10]

8.88E + 03

[11]

1.57E + 03

[148] array · 12 items

[0]

XP_027284552.1

[1]

T-complex protein 1 subunit eta isoform x2

[2]

60046.13

[3]

7.07

[4]

1.99E + 05

[5]

9.43E + 02

[6]

4.42E + 03

[7]

1.16E + 03

[8]

5.37E + 03

[9]

4.88E + 02

[10]

5.42E + 03

[11]

1.24E + 03

[149] array · 12 items

[0]

XP_027286043.1

[1]

Transforming protein rhoa isoform x1

[2]

21342.36

[3]

7.51

[4]

3.42E + 04

[5]

2.87E + 03

[6]

1.12E + 03

[7]

1.66E + 02

[8]

5.14E + 02

[9]

2.04E + 02

[10]

3.00E + 03

[11]

1.36E + 03

[150] array · 12 items

[0]

XP_027288083.1

[1]

Metalloproteinase inhibitor 1

[2]

22448.19

[3]

8.84

[4]

7.24E + 05

[5]

1.45E + 04

[6]

9.22E + 03

[7]

4.82E + 03

[8]

2.12E + 03

[9]

4.14E + 02

[10]

3.07E + 03

[11]

1.06E + 03

[151] array · 12 items

[0]

XP_027288193.1

[1]

V-type proton atpase subunit s1 isoform x2

[2]

51199.56

[3]

5.52

[4]

4.65E + 04

[5]

1.42E + 03

[6]

1.55E + 03

[7]

1.39E + 02

[8]

5.38E + 03

[9]

2.56E + 03

[10]

1.92E + 03

[11]

1.26E + 03

[152] array · 12 items

[0]

XP_027289308.1

[1]

Alpha-enolase isoform x2

[2]

47992.67

[3]

5.85

[4]

3.72E + 05

[5]

2.87E + 03

[6]

5.96E + 03

[7]

1.49E + 03

[8]

4.81E + 03

[9]

1.64E + 03

[10]

6.16E + 03

[11]

3.51E + 03

row_count

153

column_count

numeric_cells

1762

header_rows

locator

section[18]/table-wrap[1]#Tab4

gaps array · 2 items

[0]

asset:data:geo:PXD016047 not downloaded

[1]

asset:data:geo:PXD016047 licence not read

analysis object · 4 fields

state

complete

methods array · 1 item

[0] object · 10 fields

method-1

family

correlation_analysis

specific

pearson

label

Correlation analysis

dsl_operations array · 1 item

[0]

pearson_r

missing_operations array · 0 items

expressible

true

parameters object · 0 fields

data_shapes array · 1 item

[0]

paired_numeric_columns

evidence object · 3 fields

score

band

verbatim

quote

A Pearson correlation matrix was constructed using the intensities of all identified proteins.

targets array · 0 items

gaps array · 0 items

capability object · 3 fields

state

complete

requirements array · 1 item

[0] object · 6 fields

capability_id

capability:computational_analysis

label

Computational analysis platform

assay_families array · 9 items

[0]

meta_analysis

[1]

machine_learning

[2]

survival_analysis

[3]

statistical_regression

[4]

pca

[5]

molecular_docking

[6]

network_analysis

[7]

differential_expression

[8]

gwas

availability_state

owned

tier_unlocked

candidate

Automated Assays Laravel application and simulated adapters

gaps array · 0 items

readiness object · 8 fields

state

complete

tier

blocking_axis

none

blocked_on

nothing:replicable_now

axes object · 3 fields

method object · 5 fields

tier

expressible

true

required_operations array · 1 item

[0]

pearson_r

missing_operations array · 0 items

basis

The paper names the method it used and the corpus's method extractor maps it onto the DSL catalogue: pearson.

capability object · 4 fields

tier

capability_id

capability:computational_analysis

availability_state

owned

basis

The computational analysis is owned. The physical bench the paper used is not, so a physical validation cannot be run here.

data object · 6 fields

tier

reachable

true

accessions array · 1 item

[0]

PXD016047

resolved_accessions array · 1 item

[0]

PXD016047

statements array · 1 item

[0]

basis

The paper names PXD016047 in ProteomeXchange Consortium (via the PRIDE partner repository) and the accession resolves in the repository. No dataset was downloaded and no licence was read.

can_run object · 3 fields

dsl_operations array · 1 item

[0]

pearson_r

assets array · 6 items

[0]

source:pmid:32782267

[1]

data:geo:PXD016047

[2]

asset:table:pmid:32782267:1

[3]

asset:table:pmid:32782267:2

[4]

asset:table:pmid:32782267:3

[5]

asset:table:pmid:32782267:4

steps array · 1 item

[0]

run_analysis

must_build object · 5 fields

dsl_operations array · 0 items

converters array · 0 items

readers array · 0 items

capabilities array · 0 items

data_gaps array · 1 item

[0]

data:geo:PXD016047

gaps array · 0 items

review object · 5 fields

state

partial

machine_critique object · 5 fields

kind

extraction_review

reader object · 5 fields

model

MiniMax-M3.1-Flash

provider

minimax

provider_family

minimax

read_at

2026-10-31T18:22:01Z

independence

single_reader

evidence_check object · 2 fields

method

verbatim

availability

verbatim

calls

usage object · 3 fields

prompt_tokens

40872

completion_tokens

1303

cached_tokens

776

human_critique

null

stages array · 1 item

[0] object · 4 fields

extraction

state

complete

reader

MiniMax-M3.1-Flash

provider

minimax

gaps array · 3 items

[0]

review.independent_reader

[1]

review.machine_critique

[2]

review.human_critique

execution object · 5 fields

state

absent

status

not_run

mode

null

runs array · 0 items

gaps array · 1 item

[0]

execution.not_run

provenance object · 7 fields

entities array · 3 items

[0] object · 3 fields

pmid:32782267

type

paper

label

pmid:32782267

[1] object · 3 fields

source:pmid:32782267

type

manuscript

label

PMID 32782267 full text

[2] object · 3 fields

data:geo:PXD016047

type

dataset

label

GEO PXD016047

activities array · 3 items

[0] object · 4 fields

activity-reading-sci-2026-11-01

type

classification

used array · 3 items

[0] object · 3 fields

pmid:32782267

type

paper

label

pmid:32782267

[1] object · 3 fields

source:pmid:32782267

type

manuscript

label

PMID 32782267 full text

[2] object · 3 fields

data:geo:PXD016047

type

dataset

label

GEO PXD016047

agent

agent:corpus-assay-engine

[1] object · 4 fields

activity-read-32782267

type

extraction

used array · 1 item

[0]

source:pmid:32782267

agent

agent:minimax-reader

[2] object · 4 fields

activity-resolve-PXD016047

type

accession_resolution

used array · 1 item

[0]

data:geo:PXD016047

agent

agent:corpus-assay-engine

agents array · 2 items

[0] object · 3 fields

agent:corpus-assay-engine

type

software

label

Corpus assay engine

[1] object · 3 fields

agent:minimax-reader

type

software

label

MiniMax literature reader

source_run_id

reading-sci-2026-11-01

dsl_catalogue_fingerprint

343fb30756ba6ec3

capability_table_fingerprint

2cb3e42f047d2ecf

snapshot_id

ba34b49490d9bfaf

lineage object · 4 fields

parent_id

pmid:32782267

parent_hash

sha256:5669f104c7990b21f3565d2ef079517960bcc9ce2aceebf5ebad44943818cb9c

fork_of

null

generation

gaps array · 6 items

[0]

asset:data:geo:PXD016047 licence not read

[1]

asset:data:geo:PXD016047 not downloaded

[2]

execution.not_run

[3]

review.human_critique

[4]

review.independent_reader

[5]

review.machine_critique

assays array · 3 items

[0] object · 11 fields

role

data_generation

definition_id

cell_culture

definition_version

99e1195c7d6f

definition_digest

null

required_operations array · 0 items

support_state

partial

source_hashes object · 1 field

assay_lexicon

99e1195c7d6f

confidence

0.99

evidence array · 4 items

[0]

isting of 199,102 identified peptides from a CHO-K1 cell proteome. The robustness, accuracy and

[1]

b-producing CHO-K1 (CCL-61, ATCC) cells were cultured in fully chemically-defined protein-free cultur

[2]

Methods CHO cell cultures The mAb-producing CHO-K1 (CCL-61, ATCC) cells were cultured in fully

[3]

culture fluid (HCCF, collected on day 14 of CHO-K1 fed-batch cell cultures), CHO-DG44 and CHO-S

order_basis

paper_text_order:786

assay:1

[1] object · 11 fields

role

data_generation

definition_id

elisa

definition_version

99e1195c7d6f

definition_digest

null

required_operations array · 0 items

support_state

partial

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HCP content in DSP samples was determined by ELISA using a Generation III CHO HCP kit (Cygnus T

[1]

digested and analyzed accordingly (Fig. 1). ELISA analysis of these samples showed that the to

[2]

TH-MS results were not only in line with the ELISA result, but also provided critical informati

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A Pearson correlation matrix was constructed using the intensities of all identified proteins.

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Complete file

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quantified in the DSP mAb samples.", "rows": [["Protein Id", "Protein Description", "MW[Cal.]", "pI", "OM_MEAN", "OM_STDEV", "PrA_MEAN", "PrA_STDEV", "CEX_MEAN", "CEX_STDEV", "AEX_MEAN", "AEX_STDEV"], ["NP_001230908.1", "Tubulin alpha-1b chain", "49872.57", "4.94", "3.32E + 05", "3.27E + 03", "7.22E + 03", "6.02E + 03", "4.89E + 03", "2.63E + 03", "5.02E + 03", "7.77E + 02"], ["NP_001230912.1", "Aminoacyl trna synthase complex-interacting multifunctional protein 2", "35386.3", "7.69", "4.49E + 04", "2.56E + 03", "9.17E + 02", "2.03E + 02", "1.21E + 02", "1.51E + 02", "8.43E + 01", "1.03E + 02"], ["NP_001230968.1", "Elongation factor 2", "94879.53", "6.41", "2.76E + 05", "1.25E + 03", "7.25E + 03", "3.12E + 03", "6.66E + 03", "2.89E + 02", "3.30E + 04", "3.47E + 04"], ["NP_001231030.1", "Tubulin beta-5 chain", "49098.5", "4.78", "1.74E + 05", "6.85E + 03", "1.53E + 04", "4.50E + 03", "8.98E + 03", "1.86E + 03", "3.73E + 03", "5.01E + 02"], ["NP_001231196.1", "Aminoacyl trna synthase complex-interacting multifunctional protein 1", "39699.01", "9.37", "7.32E + 04", "2.43E + 03", "4.62E + 03", "1.54E + 03", "4.15E + 03", "3.58E + 02", "1.78E + 04", "3.30E + 03"], ["NP_001231202.1", "Golgi apparatus protein 1 precursor", "128275.35", "6.34", "1.09E + 05", "1.25E + 03", "4.90E + 03", "2.88E + 03", "9.20E + 03", "3.19E + 03", "1.82E + 03", "7.37E + 02"], ["NP_001231331.1", "Elongation factor 1-alpha 1", "51088.98", "9.1", "9.01E + 05", "2.23E + 04", "4.14E + 04", "4.97E + 03", "3.96E + 03", "1.43E + 03", "4.94E + 03", "1.11E + 03"], ["NP_001231783.1", "Glyceraldehyde-3-phosphate dehydrogenase", "36823.87", "8.49", "3.71E + 06", "5.56E + 04", "3.12E + 03", "9.96E + 02", "3.64E + 03", "1.26E + 03", "4.50E + 03", "1.84E + 03"], ["NP_001233603.1", "Beta-2-microglobulin precursor", "13159.28", "6.89", "3.73E + 05", "7.79E + 03", "2.49E + 03", "3.94E + 02", "2.36E + 03", "7.15E + 02", "2.67E + 03", "4.81E + 02"], ["NP_001233622.2", "Protein disulfide-isomerase precursor", 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"5.71", "4.73E + 05", "4.55E + 03", "1.17E + 04", "2.24E + 03", "2.75E + 03", "1.15E + 03", "4.32E + 03", "2.34E + 03"], ["NP_001233668.1", "Endoplasmic reticulum chaperone bip precursor", "72320.76", "5.07", "6.88E + 06", "1.36E + 05", "8.76E + 03", "5.77E + 03", "2.19E + 04", "2.21E + 04", "8.08E + 03", "3.65E + 03"], ["NP_001233670.1", "Hypoxia up-regulated protein 1 precursor", "110471.62", "5.09", "3.43E + 05", "7.59E + 03", "5.95E + 03", "1.69E + 03", "6.10E + 03", "1.63E + 03", "1.03E + 04", "2.59E + 03"], ["NP_001233673.1", "Glutathione s-transferase p 1", "23222.26", "7.64", "1.62E + 06", "4.19E + 04", "9.83E + 03", "2.55E + 03", "2.60E + 03", "8.25E + 02", "6.29E + 03", "9.27E + 02"], ["NP_001233694.1", "Peroxiredoxin-1", "22005.86", "8.22", "8.50E + 06", "8.64E + 04", "3.60E + 04", "1.86E + 04", "9.51E + 03", "2.96E + 03", "6.97E + 03", "4.04E + 03"], ["NP_001233703.1", "Protein disulfide-isomerase a3 precursor", "55844.01", "5.98", "7.40E + 05", "1.00E + 04", "1.79E + 03", 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"1.31E + 03", "6.03E + 03", "3.23E + 03"], ["XP_027244682.1", "Lipoprotein lipase isoform x2", "52415.96", "7.94", "1.39E + 05", "2.87E + 03", "1.30E + 04", "7.08E + 03", "7.10E + 03", "8.53E + 02", "6.92E + 03", "3.47E + 03"], ["XP_027245386.1", "Transketolase", "68892.71", "7.56", "7.23E + 05", "6.94E + 03", "8.12E + 03", "4.97E + 03", "5.61E + 03", "1.13E + 03", "5.71E + 03", "2.30E + 03"], ["XP_027246103.1", "Clusterin", "49430.24", "5.52", "3.08E + 06", "1.64E + 05", "8.56E + 04", "8.95E + 03", "5.42E + 03", "3.52E + 02", "4.63E + 03", "2.33E + 03"], ["XP_027246161.1", "Cathepsin b", "37487.37", "5.73", "1.61E + 06", "2.16E + 04", "7.52E + 03", "7.48E + 03", "9.78E + 03", "2.58E + 03", "3.36E + 03", "1.06E + 03"], ["XP_027246369.1", "Proteasome activator complex subunit 2", "26429.15", "5.56", "1.13E + 05", "2.36E + 03", "4.70E + 03", "1.97E + 02", "4.90E + 03", "3.34E + 02", "3.57E + 03", "2.35E + 03"], ["XP_027246859.1", "N(4)-(beta-n-acetylglucosaminyl)-l-asparaginase", "38261.44", "7.12", "1.23E + 06", "9.43E + 03", "1.15E + 04", "1.37E + 03", "6.19E + 03", "1.30E + 03", "1.29E + 04", "3.62E + 03"], ["XP_027246972.1", "Acid ceramidase isoform x2", "49761.99", "8.82", "1.50E + 06", "8.16E + 03", "1.59E + 04", "5.97E + 03", "8.56E + 03", "6.78E + 03", "6.29E + 03", "4.22E + 02"], ["XP_027247933.1", "Matrix metalloproteinase-19", "58055.66", "7.71", "2.96E + 05", "4.19E + 03", "1.28E + 04", "4.63E + 03", "3.88E + 03", "5.13E + 02", "5.59E + 03", "3.10E + 03"], ["XP_027247964.1", "Proliferation-associated protein 2g4", "43569.39", "6.26", "3.38E + 05", "3.74E + 03", "5.78E + 03", "6.43E + 02", "3.73E + 03", "1.88E + 03", "3.38E + 03", "2.79E + 03"], ["XP_027248157.1", "T-complex protein 1 subunit beta", "59161.48", "6.01", "2.12E + 05", "5.79E + 03", "1.05E + 04", "2.92E + 03", "4.84E + 03", "2.46E + 03", "5.70E + 03", "3.22E + 03"], ["XP_027248343.1", "Endoplasmin", "88686.92", "4.75", "1.27E + 06", "1.25E + 04", "1.99E + 04", "9.46E + 03", "5.93E + 03", "2.39E + 02", "5.95E + 03", "3.77E + 03"], ["XP_027248903.1", "T-complex protein 1 subunit gamma", "60267.3", "6.23", "3.02E + 05", "4.03E + 03", "4.27E + 03", "1.29E + 03", "3.08E + 04", "2.08E + 04", "3.22E + 03", "4.42E + 02"], ["XP_027249017.1", "Thrombospondin-3 isoform x1", "105716.58", "4.4", "2.32E + 04", "1.44E + 03", "3.39E + 03", "1.95E + 03", "7.44E + 03", "1.00E + 03", "3.86E + 03", "4.02E + 03"], ["XP_027249018.1", "Thrombospondin-3 isoform x2", "104721.34", "4.4", "1.79E + 05", "7.72E + 03", "7.11E + 03", "5.20E + 03", "8.59E + 03", "4.08E + 03", "1.81E + 04", "1.98E + 04"], ["XP_027249169.1", "Protein s100-a6 isoform x1", "9841.82", "5.3", "8.07E + 06", "1.67E + 05", "1.60E + 04", "5.65E + 03", "4.65E + 03", "3.21E + 03", "7.52E + 03", "7.43E + 03"], ["XP_027249297.1", "Semaphorin-3e", "85922.37", "7.95", "1.44E + 05", "2.87E + 03", "4.62E + 03", "1.20E + 03", "1.70E + 03", "3.49E + 02", "5.89E + 03", "4.68E + 03"], ["XP_027249460.1", "Extracellular matrix protein 1 isoform x1", "62257.78", "6.36", "1.72E + 04", "5.79E + 02", "1.28E + 03", "1.40E + 02", "2.50E + 03", "2.60E + 03", "6.91E + 02", "2.97E + 02"], ["XP_027249462.1", "Extracellular matrix protein 1 isoform x3", "60267.3", "6.98", "1.34E + 05", "1.89E + 03", "1.83E + 04", "1.84E + 04", "7.95E + 03", "4.12E + 03", "3.93E + 03", "1.67E + 03"], ["XP_027249711.1", "Importin-5 isoform x2", "118212.37", "4.82", "8.57E + 04", "4.24E + 02", "5.88E + 03", "9.94E + 02", "5.75E + 03", "9.18E + 02", "6.82E + 03", "6.38E + 02"], ["XP_027250030.1", "Macrophage migration inhibitory factor", "12716.95", "6.8", "8.91E + 04", "4.48E + 03", "1.40E + 03", "1.11E + 03", "6.31E + 03", "1.85E + 03", "5.03E + 03", "3.27E + 03"], ["XP_027251765.1", "Glyceraldehyde-3-phosphate dehydrogenase", "39367.26", "6.67", "3.67E + 04", "5.91E + 02", "2.07E + 03", "1.31E + 03", "1.19E + 03", "2.51E + 02", "2.12E + 03", "9.94E + 02"], ["XP_027251842.1", "Keratin, type ii cytoskeletal 2 epidermal isoform x2", "71767.85", "6.46", "1.50E + 06", "9.43E + 03", "6.13E + 03", "9.39E + 02", "3.48E + 03", "3.28E + 03", "7.69E + 03", "3.48E + 03"], ["XP_027252444.1", "Keratin, type ii cytoskeletal 1b isoform x2", "65243.5", "8.51", "1.04E + 06", "1.63E + 04", "1.28E + 03", "1.46E + 03", "4.72E + 02", "5.08E + 02", "1.58E + 03", "1.56E + 03"], ["XP_027252959.1", "Fibronectin isoform x3", "264291.46", "5.57", "3.89E + 04", "7.41E + 02", "1.21E + 03", "3.47E + 02", "7.93E + 02", "4.26E + 02", "2.39E + 04", "3.24E + 04"], ["XP_027252960.1", "Fibronectin isoform x4", "264180.88", "5.58", "1.52E + 05", "1.08E + 04", "7.22E + 03", "3.35E + 03", "2.28E + 04", "7.94E + 03", "1.34E + 04", "7.40E + 03"], ["XP_027252964.1", "Fibronectin isoform x8", "254228.48", "5.77", "8.16E + 04", "3.45E + 03", "6.85E + 03", "1.04E + 03", "3.82E + 03", "1.30E + 03", "2.41E + 03", "7.61E + 02"], ["XP_027252965.1", "Fibronectin isoform x9", "251463.92", "5.83", "2.30E + 05", "5.19E + 03", "3.07E + 03", "7.38E + 02", "5.71E + 03", "2.44E + 03", "4.73E + 03", "1.71E + 03"], ["XP_027252966.1", "Fibronectin isoform x10", "251021.59", "5.57", "6.16E + 04", "2.45E + 03", "3.39E + 03", "1.18E + 03", "3.09E + 03", "1.74E + 03", "2.11E + 03", "2.59E + 02"], ["XP_027252967.1", "Fibronectin isoform x11", "250911.01", "5.59", "1.53E + 05", "1.89E + 03", "4.97E + 03", "2.78E + 03", "9.17E + 03", "2.75E + 03", "9.79E + 03", "6.14E + 03"], ["XP_027252968.1", "Fibronectin isoform x12", "240958.61", "5.8", "1.54E + 05", "4.50E + 03", "1.46E + 04", "1.30E + 04", "2.95E + 03", "1.30E + 03", "6.90E + 03", "7.39E + 02"], ["XP_027254100.1", "Alpha-enolase isoform x2", "47992.67", "6", "4.97E + 05", "1.13E + 04", "3.68E + 03", "1.84E + 03", "1.32E + 04", "2.97E + 03", "6.68E + 03", "2.77E + 03"], ["XP_027255561.1", "Basement membrane-specific heparan sulfate proteoglycan core protein isoform x2", "485013.53", "6.12", "7.95E + 05", "1.04E + 04", "3.00E + 03", "2.41E + 02", "2.78E + 03", "3.88E + 02", "2.47E + 03", "1.50E + 02"], ["XP_027255877.1", "T-complex protein 1 subunit epsilon", "59824.97", "5.34", "3.69E + 05", "3.68E + 03", "3.49E + 03", "2.88E + 03", "1.57E + 04", "1.21E + 04", "9.98E + 03", "7.76E + 03"], ["XP_027256703.1", "Peptidyl-prolyl cis-trans isomerase c isoform x2", "23443.43", "7.77", "6.34E + 05", "1.01E + 04", "6.93E + 03", "2.65E + 03", "2.64E + 03", "1.03E + 03", "6.95E + 03", "4.44E + 03"], ["XP_027259082.1", "Transitional endoplasmic reticulum atpase isoform x2", "89129.25", "5.14", "1.47E + 05", "5.44E + 03", "3.57E + 03", "3.16E + 02", "1.49E + 03", "4.15E + 02", "3.68E + 03", "1.89E + 03"], ["XP_027259718.1", "Myosin-9 isoform x2", "216741.11", "5.53", "1.07E + 05", "2.87E + 03", "7.70E + 03", "3.08E + 03", "1.05E + 04", "2.62E + 03", "1.45E + 04", "8.49E + 03"], ["XP_027259782.1", "Eukaryotic translation initiation factor 3 subunit l", "62368.36", "5.93", "8.15E + 04", "3.27E + 03", "1.89E + 03", "4.26E + 02", "3.65E + 03", "3.71E + 03", "1.04E + 03", "4.07E + 02"], ["XP_027260200.1", "Serine protease htra1 isoform x2", "53079.46", "8.07", "3.94E + 05", "3.74E + 03", "8.62E + 03", "2.82E + 03", "5.98E + 03", "1.59E + 03", "1.10E + 04", "1.50E + 03"], ["XP_027260201.1", "Serine protease htra1 isoform x3", "51863.05", "8.07", "1.01E + 06", "1.28E + 04", "1.24E + 04", "9.94E + 03", "7.87E + 03", "1.46E + 03", "6.79E + 03", "3.04E + 03"], ["XP_027260557.1", "Lysosome-associated membrane glycoprotein 1", "44564.63", "6.31", "4.37E + 04", "5.38E + 03", "1.38E + 03", "9.38E + 02", "7.66E + 02", "4.51E + 02", "1.87E + 03", "2.03E + 03"], ["XP_027260936.1", "Inter-alpha-trypsin inhibitor heavy chain h5 isoform x2", "105274.25", "8.44", "2.58E + 05", "4.55E + 03", "8.44E + 03", "3.31E + 03", "1.21E + 04", "1.76E + 03", "1.03E + 04", "5.14E + 03"], ["XP_027261047.1", "Vimentin", "51531.31", "5.06", "6.48E + 05", "8.99E + 03", "6.89E + 03", "1.49E + 03", "6.15E + 03", "1.20E + 03", "1.08E + 04", "1.92E + 03"], ["XP_027263120.1", "Phosphoglycerate mutase 1 isoform x2", "28087.88", "6.67", "4.00E + 05", "1.14E + 04", "3.20E + 03", "5.68E + 02", "2.80E + 03", "1.33E + 03", "3.80E + 03", "2.32E + 03"], ["XP_027263985.1", "Lactadherin isoform x5", "54185.28", "8.13", "7.15E + 04", "1.60E + 03", "3.87E + 04", "2.55E + 04", "8.11E + 03", "4.41E + 03", "1.00E + 04", "2.25E + 03"], ["XP_027263987.1", "Lactadherin isoform x7", "47218.6", "8.15", "7.42E + 04", "3.09E + 03", "4.13E + 04", "2.40E + 04", "2.71E + 04", "8.87E + 03", "7.45E + 03", "2.58E + 03"], ["XP_027264128.1", "Elongation factor 1-gamma", "48324.42", "6.36", "4.77E + 05", "1.67E + 04", "1.37E + 04", "6.62E + 03", "6.75E + 04", "2.97E + 04", "1.07E + 04", "5.08E + 03"], ["XP_027264138.1", "Neutral alpha-glucosidase ab isoform x1", "106822.41", "5.72", "9.50E + 04", "3.31E + 03", "1.14E + 03", "4.22E + 02", "8.78E + 02", "3.61E + 02", "8.97E + 02", "3.95E + 02"], ["XP_027264139.1", "Neutral alpha-glucosidase ab isoform x2", "104389.6", "5.64", "1.13E + 05", "2.05E + 03", "2.83E + 03", "1.63E + 03", "2.97E + 03", "5.28E + 02", "3.32E + 03", "7.89E + 02"], ["XP_027264402.1", "Cofilin-1", "18356.65", "8.22", "1.77E + 05", "2.49E + 03", "1.63E + 04", "2.38E + 03", "7.33E + 03", "3.25E + 03", "7.15E + 03", "1.52E + 03"], ["XP_027264538.1", "Glutathione s-transferase p 2 isoform x2", "24549.25", "9.15", "6.72E + 05", "1.45E + 04", "5.93E + 03", "2.07E + 03", "3.97E + 03", "7.10E + 02", "6.04E + 03", "6.45E + 02"], ["XP_027264700.1", "Cathepsin d", "45117.54", "6.54", "3.14E + 06", "8.52E + 04", "4.20E + 03", "1.77E + 03", "3.69E + 03", "2.46E + 02", "7.13E + 03", "8.45E + 02"], ["XP_027265239.1", "Nidogen-1 isoform x3", "137785.42", "5.07", "2.26E + 05", "2.16E + 03", "8.47E + 03", "4.13E + 03", "8.31E + 03", "1.15E + 03", "1.26E + 04", "9.76E + 03"], ["XP_027265604.1", "Vesicular integral-membrane protein vip36", "39367.26", "6.46", "3.50E + 05", "4.55E + 03", "4.76E + 03", "1.73E + 03", "2.83E + 03", "2.49E + 02", "4.31E + 03", "3.65E + 03"], ["XP_027265952.1", "Nucleobindin-2 isoform x1", "47660.93", "4.97", "7.63E + 04", "2.52E + 03", "1.71E + 03", "6.58E + 02", "4.59E + 03", "3.33E + 03", "2.87E + 03", "6.01E + 02"], ["XP_027265953.1", "Nucleobindin-2 isoform x2", "46444.52", "5.05", "1.04E + 06", "2.76E + 04", "5.90E + 03", "4.83E + 02", "2.61E + 03", "8.63E + 02", "9.13E + 03", "2.25E + 03"], ["XP_027267107.1", "Peptidyl-prolyl cis-trans isomerase b", "23885.76", "9.59", "1.60E + 06", "4.71E + 03", "3.04E + 03", "3.90E + 02", "3.38E + 03", "2.36E + 02", "4.35E + 03", "1.07E + 03"], ["XP_027267400.1", "Glucosidase 2 subunit beta isoform x2", "58055.66", "4.41", "5.89E + 05", "6.68E + 03", "5.13E + 03", "1.24E + 03", "6.16E + 03", "2.30E + 03", "4.47E + 03", "6.21E + 02"], ["XP_027267710.1", "Complement c1q tumor necrosis factor-related protein 5 isoform x3", "26871.47", "5.94", "1.02E + 06", "3.98E + 04", "3.60E + 03", "2.52E + 03", "3.18E + 03", "1.11E + 03", "3.28E + 03", "9.85E + 02"], ["XP_027267915.1", "Neural cell adhesion molecule 1 isoform x4", "123852.06", "4.71", "5.10E + 05", "4.32E + 03", "8.72E + 03", "3.14E + 03", "4.99E + 03", "2.91E + 03", "7.09E + 03", "2.69E + 02"], ["XP_027267916.1", "Neural cell adhesion molecule 1 isoform x5", "93994.87", "4.8", "5.32E + 04", "1.45E + 03", "1.36E + 03", "5.10E + 02", "8.44E + 02", "9.77E + 01", "2.43E + 03", "3.37E + 02"], ["XP_027267917.1", "Neural cell adhesion molecule 1 isoform x6", "93884.29", "4.79", "2.57E + 05", "8.73E + 03", "3.11E + 03", "3.85E + 02", "1.78E + 03", "8.40E + 02", "8.69E + 03", "2.27E + 03"], ["XP_027267919.1", "Neural cell adhesion molecule 1 isoform x8", "93773.71", "4.8", "1.11E + 05", "3.30E + 03", "5.21E + 03", "3.36E + 03", "2.83E + 03", "3.41E + 03", "1.36E + 03", "2.69E + 02"], ["XP_027267920.1", "Neural cell adhesion molecule 1 isoform x9", "80393.26", "4.77", "2.91E + 05", "2.45E + 03", "8.57E + 03", "3.57E + 03", "2.03E + 03", "1.79E + 02", "5.70E + 03", "1.60E + 03"], ["XP_027267921.1", "Neural cell adhesion molecule 1 isoform x10", "80282.68", "4.79", "1.15E + 05", "2.05E + 03", "9.81E + 03", "1.40E + 03", "3.19E + 03", "1.23E + 03", "3.04E + 03", "3.02E + 02"], ["XP_027268152.1", "T-complex protein 1 subunit theta isoform x2", "60599.05", "5.43", "3.22E + 05", "4.71E + 02", "3.87E + 03", "1.01E + 03", "1.34E + 04", "3.84E + 03", "9.09E + 03", "5.29E + 03"], ["XP_027268153.1", "T-complex protein 1 subunit theta isoform x3", "54959.35", "5.19", "2.89E + 05", "4.50E + 03", "4.77E + 03", "2.10E + 03", "1.82E + 03", "2.87E + 01", "1.98E + 03", "8.82E + 02"], ["XP_027269607.1", "Beta-glucuronidase isoform x4", "72431.34", "6.28", "1.78E + 05", "5.72E + 03", "4.30E + 03", "3.84E + 03", "2.62E + 03", "6.07E + 02", "1.72E + 03", "1.38E + 02"], ["XP_027269616.1", "T-complex protein 1 subunit zeta", "58719.15", "6.46", "1.72E + 05", "3.09E + 03", "6.45E + 03", "1.93E + 03", "2.54E + 03", "1.32E + 03", "5.12E + 03", "4.02E + 03"], ["XP_027269644.1", "Gtp-binding nuclear protein ran isoform x2", "23885.76", "7.01", "5.37E + 05", "1.03E + 04", "6.36E + 03", "2.76E + 03", "7.70E + 03", "4.69E + 03", "6.51E + 03", "3.57E + 03"], ["XP_027269956.1", "Phospholipase b-like 2", "64690.59", "5.9", "1.10E + 06", "4.78E + 04", "3.95E + 04", "4.71E + 04", "1.53E + 04", "1.01E + 04", "7.36E + 03", "1.74E + 03"], ["XP_027270355.1", "Transforming protein rhoa", "21342.36", "5.83", "1.56E + 05", "1.25E + 03", "2.82E + 03", "4.60E + 02", "2.38E + 03", "5.30E + 02", "3.50E + 03", "1.43E + 03"], ["XP_027270673.1", "Pyruvate kinase pkm isoform x1", "58719.15", "6.69", "8.65E + 05", "1.64E + 04", "1.27E + 04", "7.34E + 03", "2.17E + 03", "6.46E + 02", "4.50E + 03", "2.64E + 03"], ["XP_027270674.1", "Pyruvate kinase pkm isoform x2", "58719.15", "6.88", "1.09E + 06", "2.36E + 04", "8.46E + 03", "3.88E + 03", "6.72E + 03", "3.48E + 03", "5.74E + 03", "2.39E + 03"], ["XP_027270675.1", "Pyruvate kinase pkm isoform x3", "57060.42", "8.65", "8.09E + 05", "2.66E + 04", "1.53E + 04", "5.98E + 03", "4.50E + 03", "3.28E + 03", "8.36E + 03", "2.70E + 03"], ["XP_027270716.1", "Lysyl oxidase homolog 1 isoform x2", "67012.81", "6.57", "1.94E + 05", "4.71E + 02", "7.19E + 03", "3.63E + 03", "8.20E + 03", "2.73E + 03", "7.55E + 03", "1.64E + 03"], ["XP_027270812.1", "Chondroitin sulfate proteoglycan 4", "256882.45", "5.41", "2.63E + 05", "5.72E + 03", "1.03E + 04", "9.31E + 03", "1.06E + 04", "4.45E + 03", "1.45E + 04", "6.25E + 03"], ["XP_027271096.1", "Beta-galactosidase isoform x3", "75859.39", "8.58", "4.32E + 04", "2.36E + 03", "1.06E + 03", "1.24E + 02", "1.81E + 03", "7.72E + 02", "9.83E + 03", "2.59E + 03"], ["XP_027271097.1", "Beta-galactosidase isoform x4", "73868.91", "6.71", "3.52E + 05", "7.41E + 03", "4.27E + 03", "5.47E + 02", "4.18E + 03", "1.49E + 03", "5.98E + 03", "2.17E + 03"], ["XP_027271619.1", "Elongation factor 1-alpha 1", "50646.65", "7.9", "8.78E + 05", "4.10E + 04", "1.19E + 02", "8.16E + 01", "5.76E + 01", "5.97E + 01", "1.89E + 02", "1.39E + 02"], ["XP_027271991.1", "Malate dehydrogenase, mitochondrial isoform x2", "37376.78", "8.93", "1.35E + 05", "4.03E + 03", "3.97E + 03", "1.35E + 03", "3.21E + 03", "8.13E + 02", "3.77E + 03", "8.51E + 02"], ["XP_027272021.1", "Plasminogen activator inhibitor 1 isoform x2", "44454.04", "7.2", "4.74E + 06", "1.02E + 05", "7.43E + 03", "2.19E + 03", "7.02E + 03", "2.94E + 03", "9.84E + 03", "5.02E + 03"], ["XP_027272044.1", "Procollagen c-endopeptidase enhancer 1", "51752.47", "8.16", "2.76E + 05", "7.59E + 03", "7.26E + 03", "3.63E + 03", "5.78E + 03", "1.27E + 03", "5.10E + 03", "3.45E + 02"], ["XP_027272591.1", "Complement c3", "184229.95", "6.2", "6.09E + 04", "2.70E + 03", "5.08E + 03", "1.33E + 03", "1.07E + 04", "3.60E + 03", "5.28E + 03", "1.91E + 03"], ["XP_027272776.1", "Laminin subunit beta-1 isoform x5", "197499.81", "4.78", "2.42E + 05", "4.71E + 02", "6.80E + 03", "3.52E + 03", "1.80E + 03", "5.07E + 02", "1.12E + 04", "5.03E + 03"], ["XP_027272779.1", "Laminin subunit beta-1 isoform x3", "186662.75", "4.76", "1.91E + 05", "5.44E + 03", "3.96E + 03", "4.81E + 02", "3.41E + 03", "1.03E + 03", "6.88E + 03", "2.99E + 03"], ["XP_027272780.1", "Laminin subunit beta-1 isoform x4", "162666.42", "4.7", "6.79E + 04", "1.57E + 03", "1.64E + 03", "9.69E + 02", "2.11E + 03", "9.24E + 02", "4.12E + 03", "5.00E + 02"], ["XP_027273163.1", "Laminin subunit gamma-1 isoform x2", "177705.6", "4.99", "1.16E + 05", "3.86E + 03", "9.84E + 03", "9.17E + 03", "4.12E + 03", "1.37E + 03", "4.26E + 03", "3.94E + 02"], ["XP_027274751.1", "Immunoglobulin superfamily member 8 isoform x3", "66902.23", "7.94", "7.24E + 04", "1.28E + 03", "2.32E + 03", "6.47E + 02", "6.75E + 03", "4.73E + 03", "3.08E + 03", "5.51E + 02"], ["XP_027274961.1", "Legumain", "48435", "6.07", "3.01E + 06", "3.40E + 04", "6.31E + 03", "1.19E + 03", "5.76E + 03", "2.85E + 03", "6.16E + 03", "4.75E + 03"], ["XP_027275654.1", "Cathepsin z", "33838.15", "7.52", "3.29E + 06", "4.64E + 04", "1.44E + 04", "6.08E + 03", "8.88E + 03", "5.11E + 03", "5.29E + 03", "1.74E + 03"], ["XP_027275687.1", "Laminin subunit alpha-5", "413024.52", "6.49", "8.50E + 04", "1.33E + 03", "8.53E + 03", "2.29E + 03", "5.54E + 03", "3.87E + 03", "4.65E + 03", "1.58E + 03"], ["XP_027276427.1", "Nucleobindin-1 isoform x3", "50536.07", "5.14", "7.26E + 05", "8.60E + 03", "2.58E + 03", "9.22E + 02", "5.52E + 03", "2.30E + 03", "1.06E + 04", "6.58E + 03"], ["XP_027277053.1", "Protein-glutamine gamma-glutamyltransferase 2", "75859.39", "5.08", "1.08E + 05", "3.30E + 03", "1.76E + 03", "7.39E + 02", "1.03E + 03", "6.81E + 02", "4.04E + 03", "2.16E + 03"], ["XP_027278026.1", "Thrombospondin-1 isoform x2", "129381.17", "4.7", "1.12E + 06", "2.36E + 04", "9.32E + 03", "3.97E + 03", "6.71E + 03", "9.85E + 02", "7.11E + 03", "1.68E + 03"], ["XP_027278163.1", "Catalase isoform x1", "61373.12", "8.29", "7.38E + 04", "3.74E + 03", "2.23E + 03", "7.48E + 02", "2.00E + 03", "1.10E + 03", "7.40E + 03", "1.58E + 03"], ["XP_027278164.1", "Catalase isoform x2", "53742.95", "7.33", "7.48E + 04", "1.10E + 03", "2.48E + 03", "2.46E + 02", "2.36E + 03", "6.59E + 02", "7.45E + 03", "8.38E + 02"], ["XP_027279237.1", "Matrix metalloproteinase-9", "78513.36", "5.6", "4.31E + 04", "2.60E + 03", "4.31E + 03", "1.59E + 03", "1.05E + 04", "3.66E + 03", "5.71E + 03", "2.24E + 03"], ["XP_027279240.1", "Lysosomal protective protein", "54517.02", "5.64", "1.34E + 06", "0.00E + 00", "3.44E + 03", "1.21E + 03", "6.16E + 03", "1.66E + 03", "4.86E + 03", "3.13E + 03"], ["XP_027279242.1", "Phospholipid transfer protein isoform x2", "49761.99", "5.94", "3.95E + 05", "2.05E + 03", "7.01E + 03", "1.74E + 03", "2.75E + 03", "1.23E + 03", "5.27E + 03", "1.83E + 03"], ["XP_027279907.1", "Insulin-like growth factor-binding protein 4", "28087.88", "6.78", "2.80E + 05", "4.71E + 03", "2.10E + 03", "1.78E + 03", "4.60E + 02", "1.44E + 02", "4.72E + 02", "7.07E + 01"], ["XP_027280118.1", "Nucleoside diphosphate kinase b", "16808.49", "7.78", "8.71E + 05", "8.65E + 03", "2.13E + 03", "4.30E + 02", "5.08E + 03", "3.38E + 03", "3.93E + 03", "7.21E + 02"], ["XP_027280121.1", "Nucleoside diphosphate kinase a isoform x1", "16808.49", "5.96", "4.03E + 05", "1.02E + 04", "1.60E + 04", "7.06E + 03", "2.90E + 04", "1.91E + 04", "1.83E + 04", "2.18E + 04"], ["XP_027280122.1", "Nucleoside diphosphate kinase a isoform x2", "12274.62", "5", "7.94E + 05", "4.24E + 03", "9.15E + 03", "1.12E + 03", "5.37E + 03", "7.92E + 02", "5.05E + 03", "1.53E + 03"], ["XP_027280299.1", "Emilin-1 isoform x1", "112462.1", "5.24", "1.37E + 05", "6.18E + 03", "2.13E + 03", "6.39E + 02", "3.16E + 03", "5.94E + 02", "9.26E + 03", "2.71E + 03"], ["XP_027280300.1", "Emilin-1 isoform x2", "101625.04", "5.09", "1.22E + 05", "1.25E + 03", "5.39E + 03", "8.94E + 02", "2.52E + 03", "6.40E + 02", "3.39E + 03", "2.41E + 03"], ["XP_027281003.1", "Nucleophosmin isoform x2", "32290", "4.61", "9.43E + 05", "1.05E + 04", "9.38E + 03", "7.51E + 03", "4.03E + 03", "1.60E + 03", "5.94E + 03", "2.13E + 03"], ["XP_027281136.1", "Fatty acid synthase isoform x2", "276787.25", "5.95", "9.64E + 04", "2.36E + 03", "7.46E + 03", "6.20E + 03", "7.63E + 03", "9.34E + 02", "6.81E + 03", "3.24E + 03"], ["XP_027281297.1", "Lysosomal alpha-glucosidase", "104942.51", "5.65", "6.10E + 05", "2.82E + 04", "1.64E + 04", "9.02E + 03", "1.80E + 04", "2.88E + 03", "4.56E + 03", "1.55E + 03"], ["XP_027281318.1", "Galectin-3-binding protein", "63474.18", "5.06", "9.51E + 05", "2.46E + 04", "1.26E + 04", "5.04E + 03", "8.36E + 03", "5.68E + 03", "6.46E + 03", "3.00E + 03"], ["XP_027281357.1", "Septin-9 isoform x4", "65464.66", "7.16", "7.81E + 04", "9.63E + 02", "1.28E + 04", "3.83E + 03", "3.51E + 03", "2.62E + 03", "3.64E + 03", "1.17E + 03"], ["XP_027281359.1", "Septin-9 isoform x5", "37045.04", "7.1", "7.81E + 04", "3.14E + 03", "8.26E + 02", "3.54E + 02", "4.29E + 02", "1.56E + 02", "6.13E + 02", "3.17E + 02"], ["XP_027282087.1", "Retinoid-inducible serine carboxypeptidase", "50314.9", "5.39", "4.82E + 05", "1.41E + 03", "3.12E + 03", "1.43E + 03", "2.39E + 03", "1.85E + 03", "2.59E + 03", "9.03E + 02"], ["XP_027282154.1", "Clathrin heavy chain 1 isoform x3", "185225.19", "5.48", "1.29E + 05", "3.56E + 03", "3.61E + 04", "3.82E + 04", "6.45E + 03", "2.07E + 03", "2.04E + 03", "7.87E + 02"], ["XP_027282301.1", "C-c motif chemokine 2", "15813.25", "9.32", "3.12E + 06", "2.16E + 04", "2.03E + 03", "4.27E + 02", "1.22E + 03", "3.98E + 02", "4.94E + 03", "2.68E + 03"], ["XP_027282549.1", "Pigment epithelium-derived factor isoform x2", "46223.36", "6.43", "3.52E + 05", "3.74E + 03", "7.57E + 03", "4.32E + 03", "4.18E + 03", "1.21E + 03", "1.60E + 04", "1.49E + 04"], ["XP_027282819.1", "Eukaryotic initiation factor 4a-i", "44896.37", "5.32", "1.30E + 05", "6.13E + 03", "4.71E + 03", "1.77E + 03", "4.04E + 03", "1.25E + 03", "5.36E + 03", "1.55E + 03"], ["XP_027283255.1", "Sparc isoform x4", "33838.15", "4.75", "1.27E + 05", "4.71E + 02", "2.26E + 03", "1.06E + 03", "3.57E + 03", "8.75E + 02", "4.94E + 03", "9.27E + 02"], ["XP_027283783.1", "Granulins isoform x2", "65464.66", "5.97", "1.15E + 06", "2.05E + 04", "4.31E + 03", "3.70E + 03", "3.09E + 03", "5.03E + 02", "2.42E + 03", "3.59E + 02"], ["XP_027284007.1", "Keratin, type i cytoskeletal 10 isoform x3", "62700.11", "5.04", "1.14E + 06", "3.30E + 04", "1.34E + 04", "6.51E + 03", "1.34E + 04", "9.83E + 03", "6.90E + 03", "7.36E + 02"], ["XP_027284023.1", "Complement c1r subcomponent", "77960.45", "5.71", "4.54E + 05", "1.17E + 04", "1.28E + 04", "2.44E + 03", "9.64E + 03", "2.48E + 03", "7.56E + 03", "9.74E + 02"], ["XP_027284024.1", "Complement c1r subcomponent-like protein", "53742.95", "6.31", "1.27E + 05", "4.03E + 03", "1.73E + 04", "2.46E + 03", "1.04E + 04", "1.90E + 03", "7.97E + 03", "2.96E + 03"], ["XP_027284060.1", "Triosephosphate isomerase isoform x2", "27534.97", "6.13", "3.21E + 05", "4.50E + 03", "2.85E + 03", "1.18E + 03", "7.05E + 03", "5.43E + 02", "8.88E + 03", "1.57E + 03"], ["XP_027284552.1", "T-complex protein 1 subunit eta isoform x2", "60046.13", "7.07", "1.99E + 05", "9.43E + 02", "4.42E + 03", "1.16E + 03", "5.37E + 03", "4.88E + 02", "5.42E + 03", "1.24E + 03"], ["XP_027286043.1", "Transforming protein rhoa isoform x1", "21342.36", "7.51", "3.42E + 04", "2.87E + 03", "1.12E + 03", "1.66E + 02", "5.14E + 02", "2.04E + 02", "3.00E + 03", "1.36E + 03"], ["XP_027288083.1", "Metalloproteinase inhibitor 1", "22448.19", "8.84", "7.24E + 05", "1.45E + 04", "9.22E + 03", "4.82E + 03", "2.12E + 03", "4.14E + 02", "3.07E + 03", "1.06E + 03"], ["XP_027288193.1", "V-type proton atpase subunit s1 isoform x2", "51199.56", "5.52", "4.65E + 04", "1.42E + 03", "1.55E + 03", "1.39E + 02", "5.38E + 03", "2.56E + 03", "1.92E + 03", "1.26E + 03"], ["XP_027289308.1", "Alpha-enolase isoform x2", "47992.67", "5.85", "3.72E + 05", "2.87E + 03", "5.96E + 03", "1.49E + 03", "4.81E + 03", "1.64E + 03", "6.16E + 03", "3.51E + 03"]], "row_count": 153, "column_count": 12, "numeric_cells": 1762, "header_rows": 1, "locator": "section[18]/table-wrap[1]#Tab4"}}], "gaps": ["asset:data:geo:PXD016047 not downloaded", "asset:data:geo:PXD016047 licence not read"]}, "analysis": {"state": "complete", "methods": [{"id": "method-1", "family": "correlation_analysis", "specific": "pearson", "label": "Correlation analysis", "dsl_operations": ["pearson_r"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["paired_numeric_columns"], "evidence": {"score": 1.0, "band": "verbatim", "quote": "A Pearson correlation matrix was constructed using the intensities of all identified proteins."}}], "targets": [], "gaps": []}, "capability": {"state": "complete", "requirements": [{"capability_id": "capability:computational_analysis", "label": "Computational analysis platform", "assay_families": ["meta_analysis", "machine_learning", "survival_analysis", "statistical_regression", "pca", "molecular_docking", "network_analysis", "differential_expression", "gwas"], "availability_state": "owned", "tier_unlocked": "R1", "candidate": "Automated Assays Laravel application and simulated adapters"}], "gaps": []}, "readiness": {"state": "complete", "tier": "R1", "blocking_axis": "none", "blocked_on": "nothing:replicable_now", "axes": {"method": {"tier": "R1", "expressible": true, "required_operations": ["pearson_r"], "missing_operations": [], "basis": "The paper names the method it used and the corpus's method extractor maps it onto the DSL catalogue: pearson."}, "capability": {"tier": "R1", "capability_id": "capability:computational_analysis", "availability_state": "owned", "basis": "The computational analysis is owned. The physical bench the paper used is not, so a physical validation cannot be run here."}, "data": {"tier": "R1", "reachable": true, "accessions": ["PXD016047"], "resolved_accessions": ["PXD016047"], "statements": ["The raw DDA data files for library generation, the search result (group files), the CHO spectral library, and the SWATH-MS acquisition data applied in the current study have been deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org)34via the PRIDE partner repository35,36 with the data set identifier PXD01604728."], "basis": "The paper names PXD016047 in ProteomeXchange Consortium (via the PRIDE partner repository) and the accession resolves in the repository. No dataset was downloaded and no licence was read."}}, "can_run": {"dsl_operations": ["pearson_r"], "assets": ["source:pmid:32782267", "data:geo:PXD016047", "asset:table:pmid:32782267:1", "asset:table:pmid:32782267:2", "asset:table:pmid:32782267:3", "asset:table:pmid:32782267:4"], "steps": ["run_analysis"]}, "must_build": {"dsl_operations": [], "converters": [], "readers": [], "capabilities": [], "data_gaps": ["data:geo:PXD016047"]}, "gaps": []}, "review": {"state": "partial", "machine_critique": {"kind": "extraction_review", "reader": {"model": "MiniMax-M3.1-Flash", "provider": "minimax", "provider_family": "minimax", "read_at": "2026-10-31T18:22:01Z", "independence": "single_reader"}, "evidence_check": {"method": "verbatim", "availability": "verbatim"}, "calls": 3, "usage": {"prompt_tokens": 40872, "completion_tokens": 1303, "cached_tokens": 776}}, "human_critique": null, "stages": [{"id": "extraction", "state": "complete", "reader": "MiniMax-M3.1-Flash", "provider": "minimax"}], "gaps": ["review.independent_reader", "review.machine_critique", "review.human_critique"]}, "execution": {"state": "absent", "status": "not_run", "mode": null, "runs": [], "gaps": ["execution.not_run"]}, "provenance": {"entities": [{"id": "pmid:32782267", "type": "paper", "label": "pmid:32782267"}, {"id": "source:pmid:32782267", "type": "manuscript", "label": "PMID 32782267 full text"}, {"id": "data:geo:PXD016047", "type": "dataset", "label": "GEO PXD016047"}], "activities": [{"id": "activity-reading-sci-2026-11-01", "type": "classification", "used": [{"id": "pmid:32782267", "type": "paper", "label": "pmid:32782267"}, {"id": "source:pmid:32782267", "type": "manuscript", "label": "PMID 32782267 full text"}, {"id": "data:geo:PXD016047", "type": "dataset", "label": "GEO PXD016047"}], "agent": "agent:corpus-assay-engine"}, {"id": "activity-read-32782267", "type": "extraction", "used": ["source:pmid:32782267"], "agent": "agent:minimax-reader"}, {"id": "activity-resolve-PXD016047", "type": "accession_resolution", "used": ["data:geo:PXD016047"], "agent": "agent:corpus-assay-engine"}], "agents": [{"id": "agent:corpus-assay-engine", "type": "software", "label": "Corpus assay engine"}, {"id": "agent:minimax-reader", "type": "software", "label": "MiniMax literature reader"}], "source_run_id": "reading-sci-2026-11-01", "dsl_catalogue_fingerprint": "343fb30756ba6ec3", "capability_table_fingerprint": "2cb3e42f047d2ecf", "snapshot_id": "ba34b49490d9bfaf"}, "lineage": {"parent_id": "pmid:32782267", "parent_hash": "sha256:5669f104c7990b21f3565d2ef079517960bcc9ce2aceebf5ebad44943818cb9c", "fork_of": null, "generation": 5}, "gaps": ["asset:data:geo:PXD016047 licence not read", "asset:data:geo:PXD016047 not downloaded", "execution.not_run", "review.human_critique", "review.independent_reader", "review.machine_critique"], "assays": [{"role": "data_generation", "definition_id": "cell_culture", "definition_version": "99e1195c7d6f", "definition_digest": null, "required_operations": [], "support_state": "partial", "source_hashes": {"assay_lexicon": "99e1195c7d6f"}, "confidence": 0.99, "evidence": ["isting of 199,102 identified peptides from a CHO-K1 cell proteome. The robustness, accuracy and", "b-producing CHO-K1 (CCL-61, ATCC) cells were cultured in fully chemically-defined protein-free cultur", "Methods CHO cell cultures The mAb-producing CHO-K1 (CCL-61, ATCC) cells were cultured in fully", "culture fluid (HCCF, collected on day 14 of CHO-K1 fed-batch cell cultures), CHO-DG44 and CHO-S"], "order_basis": "paper_text_order:786", "id": "assay:1"}, {"role": "data_generation", "definition_id": "elisa", "definition_version": "99e1195c7d6f", "definition_digest": null, "required_operations": [], "support_state": "partial", "source_hashes": {"assay_lexicon": "99e1195c7d6f"}, "confidence": 0.99, "evidence": ["HCP content in DSP samples was determined by ELISA using a Generation III CHO HCP kit (Cygnus T", "digested and analyzed accordingly (Fig. 1). ELISA analysis of these samples showed that the to", "TH-MS results were not only in line with the ELISA result, but also provided critical informati"], "order_basis": "paper_text_order:5269", "id": "assay:2"}, {"role": "analysis", "definition_id": "correlation_analysis", "definition_version": "f2132e96ae6c7a4e", "definition_digest": null, "required_operations": ["pearson_r"], "support_state": "supported", "source_hashes": {"dsl_catalogue": "f2132e96ae6c7a4e"}, "confidence": 1.0, "evidence": ["A Pearson correlation matrix was constructed using the intensities of all identified proteins."], "order_basis": "consumes_earlier_output", "id": "assay:3"}]}