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pmid:34880861
CD247, a Potential T Cell-Derived Disease Severity and Prognostic Biomarker in Patients With Idiopathic Pulmonary Fibrosis.
Yupeng Li · Shibin Chen · Xincheng Li · Xue Wang · Huiwen Li · Shangwei Ning · Hong Chen
Frontiers in immunology · 2021 doi:10.3389/fimmu.2021.762594
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Complete file
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The CD247 molecule (CD247, as known as T-cell surface glycoprotein CD3 zeta chain) has been reported as a susceptibility locus in systemic sclerosis, but its correlation with IPF remains unclear.\nMethods: Datasets were acquired by researching the Gene Expression Omnibus (GEO). CD247 was identified as the hub gene associated with percent predicted diffusion capacity of the lung for carbon monoxide (Dlco% predicted) and prognosis according to Pearson correlation, logistic regression, and survival analysis.\nResults: CD247 is significantly downregulated in patients with IPF compared with controls in both blood and lung tissue samples. Moreover, CD247 is significantly positively associated with Dlco% predicted in blood and lung tissue samples. Patients with low-expression CD247 had shorter transplant-free survival (TFS) time and more composite end-point events (CEP, death, or decline in FVC >10% over a 6-month period) compared with patients with high-expression CD247 (blood). Moreover, in the follow-up 1st, 3rd, 6th, and 12th months, low expression of CD247 was still the risk factor of CEP in the GSE93606 dataset (blood). Thirteen genes were found to interact with CD247 according to the protein-protein interaction network, and the 14 genes including CD247 were associated with the functions of T cells and natural killer (NK) cells such as PD-L1 expression and PD-1 checkpoint pathway and NK cell-mediated cytotoxicity. Furthermore, we also found that a low expression of CD247 might be associated with a lower activity of TIL (tumor-infiltrating lymphocytes), checkpoint, and cytolytic activity and a higher activity of macrophages and neutrophils.\nConclusion: These results imply that CD247 may be a potential T cell-derived disease severity and prognostic biomarker for IPF.", "claims": [{"id": "claim-method", "statement": "CD247 was identified as the hub gene associated with percent predicted diffusion capacity of the lung for carbon monoxide (Dlco% predicted) and prognosis according to Pearson correlation, logistic regression, and survival analysis.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:34880861", "locator": "sections[0] \"Abstract\" paragraph 2", "quote": "CD247 was identified as the hub gene associated with percent predicted diffusion capacity of the lung for carbon monoxide (Dlco% predicted) and prognosis according to Pearson correlation, logistic regression, and survival analysis."}], "state": "complete"}, {"id": "claim-data-access", "statement": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). 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The annotated gene set file used in ssGSEA were available in Supplementary Material 2 ."}], "state": "complete"}], "gaps": []}, "experiment": {"state": "complete", "objective": "", "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The claim, method and evidence span published with the source article.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:34880861"], "outputs": ["the published estimate and its evidence"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the source data from the named repository", "kind": "data-preparation", "state": "complete", "blocked_on": null, "description": "The GEO series accession resolves and its sample accessions are listed. This lane did not download the dataset or read its licence.", "duration_hours": null, "parameters": {}, "inputs": ["data:geo:GSE110147"], "outputs": ["the source data with its repository provenance"], "instruments": [], "reagents": []}, {"id": "run_analysis", "order": 3, "name": "Run the published analysis", "kind": "analysis", "state": "complete", "blocked_on": null, "description": "Apply the paper's statistical method to the resolved series and compare the result with the published target.", "duration_hours": null, "parameters": {}, "inputs": ["data:geo:GSE110147"], "outputs": ["the replicated result and its comparison"], "instruments": [], "reagents": []}], "materials": [], "instruments": [], "reagents": [], "conditions": {}, "gaps": []}, "data": {"state": "partial", "assets": [{"id": "source:pmid:34880861", "role": "manuscript", "format": "xml", "media_type": "application/xml", "uri": "https://doi.org/10.3389/fimmu.2021.762594", "sha256": "sha256:61e9cce774049b29ef90cf05bd9db080c4fb43dc711b295843654cc8ff108e50", "bytes": 51492, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "10.3389/fimmu.2021.762594", "version": null, "note": "Full article fetched from PMC; the checksum covers the rendered section body, not the original XML bytes.", "structure": {"pmcid": "PMC8645971", "source": "europe_pmc_fulltext", "coverage": "whole_body", "text_hash_scope": "rendered_section_body"}}, {"id": "data:geo:GSE110147", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE110147", "version": null, "note": "Publicly available datasets were analyzed in this study. 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The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM2978752", "GSM2978753", "GSM2978754", "GSM2978755", "GSM2978756", "GSM2978757", "GSM2978758", "GSM2978759", "GSM2978760", "GSM2978761", "GSM2978762", "GSM2978763", "GSM2978764", "GSM2978765", "GSM2978766", "GSM2978767", "GSM2978768", "GSM2978769", "GSM2978770", "GSM2978771", "GSM2978772", "GSM2978773", "GSM2978774", "GSM2978775", "GSM2978776", "GSM2978777", "GSM2978778", "GSM2978779", "GSM2978780", "GSM2978781", "GSM2978782", "GSM2978783", "GSM2978784", "GSM2978785", "GSM2978786", "GSM2978787", "GSM2978788", "GSM2978789", "GSM2978790", "GSM2978791", "GSM2978792", "GSM2978793", "GSM2978794", "GSM2978795", "GSM2978796", "GSM2978797", "GSM2978798", "GSM2978799"], "sample_count": 48, "group_sizes": null, "group_sizes_basis": null, "platform": "6244", "taxon": "Homo sapiens", "title": "Gene expression profiling of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE132607", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE132607", "version": null, "note": "Publicly available datasets were analyzed in this study. 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The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM3879744", "GSM3879745", "GSM3879746", "GSM3879747", "GSM3879748", "GSM3879749", "GSM3879750", "GSM3879751", "GSM3879752", "GSM3879753", "GSM3879754", "GSM3879755", "GSM3879756", "GSM3879757", "GSM3879758", "GSM3879759", "GSM3879760", "GSM3879761", "GSM3879762", "GSM3879763", "GSM3879764", "GSM3879765", "GSM3879766", "GSM3879767", "GSM3879768", "GSM3879769", "GSM3879770", "GSM3879771", "GSM3879772", "GSM3879773", "GSM3879774", "GSM3879775", "GSM3879776", "GSM3879777", "GSM3879778", "GSM3879779", "GSM3879780", "GSM3879781", "GSM3879782", "GSM3879783", "GSM3879784", "GSM3879785", "GSM3879786", "GSM3879787", "GSM3879788", "GSM3879789", "GSM3879790", "GSM3879791", "GSM3879792", "GSM3879793", "GSM3879794", "GSM3879795", "GSM3879796", "GSM3879797", "GSM3879798", "GSM3879799", "GSM3879800", "GSM3879801", "GSM3879802", "GSM3879803", "GSM3879804", "GSM3879805", "GSM3879806", "GSM3879807", "GSM3879808", "GSM3879809", "GSM3879810", "GSM3879811", "GSM3879812", "GSM3879813", "GSM3879814", "GSM3879815", "GSM3879816", "GSM3879817", "GSM3879818", "GSM3879819", "GSM3879820", "GSM3879821", "GSM3879822", "GSM3879823", "GSM3879824", "GSM3879825", "GSM3879826", "GSM3879827", "GSM3879828", "GSM3879829", "GSM3879830", "GSM3879831", "GSM3879832", "GSM3879833", "GSM3879834", "GSM3879835", "GSM3879836", "GSM3879837", "GSM3879838", "GSM3879839", "GSM3879840", "GSM3879841", "GSM3879842", "GSM3879843", "GSM3879844", "GSM3879845", "GSM3879846", "GSM3879847", "GSM3879848", "GSM3879849", "GSM3879850", "GSM3879851", "GSM3879852", "GSM3879853", "GSM3879854", "GSM3879855", "GSM3879856", "GSM3879857", "GSM3879858", "GSM3879859", "GSM3879860", "GSM3879861", "GSM3879862", "GSM3879863", "GSM3879864", "GSM3879865", "GSM3879866", "GSM3879867", "GSM3879868", "GSM3879869", "GSM3879870", "GSM3879871", "GSM3879872", "GSM3879873", "GSM3879874", "GSM3879875", "GSM3879876", "GSM3879877", "GSM3879878", "GSM3879879", "GSM3879880", "GSM3879881", "GSM3879882", "GSM3879883", "GSM3879884", "GSM3879885", "GSM3879886", "GSM3879887", "GSM3879888", "GSM3879889", "GSM3879890", "GSM3879891", "GSM3879892", "GSM3879893", "GSM3879894", "GSM3879895", "GSM3879896", "GSM3879897", "GSM3879898", "GSM3879899", "GSM3879900", "GSM3879901", "GSM3879902", "GSM3879903", "GSM3879904", "GSM3879905", "GSM3879906", "GSM3879907", "GSM3879908", "GSM3879909", "GSM3879910", "GSM3879911", "GSM3879912", "GSM3879913", "GSM3879914", "GSM3879915", "GSM3879916", "GSM3879917", "GSM3879918", "GSM3879919", "GSM3879920", "GSM3879921", "GSM3879922", "GSM3879923", "GSM3879924", "GSM3879925", "GSM3879926", "GSM3879927", "GSM3879928", "GSM3879929", "GSM3879930", "GSM3879931", "GSM3879932", "GSM3879933", "GSM3879934", "GSM3879935", "GSM3879936", "GSM3879937", "GSM3879938", "GSM3879939", "GSM3879940", "GSM3879941", "GSM3879942", "GSM3879943", "GSM3879944", "GSM3879945", "GSM3879946", "GSM3879947", "GSM3879948", "GSM3879949", "GSM3879950", "GSM3879951", "GSM3879952", "GSM3879953", "GSM3879954", "GSM3879955", "GSM3879956", "GSM3879957", "GSM3879958", "GSM3879959", "GSM3879960", "GSM3879961", "GSM3879962", "GSM3879963", "GSM3879964", "GSM3879965", "GSM3879966", "GSM3879967", "GSM3879968", "GSM3879969", "GSM3879970", "GSM3879971", "GSM3879972", "GSM3879973", "GSM3879974", "GSM3879975", "GSM3879976", "GSM3879977", "GSM3879978", "GSM3879979", "GSM3879980", "GSM3879981", "GSM3879982", "GSM3879983", "GSM3879984", "GSM3879985", "GSM3879986", "GSM3879987", "GSM3879988", "GSM3879989", "GSM3879990", "GSM3879991", "GSM3879992", "GSM3879993", "GSM3879994", "GSM3879995", "GSM3879996", "GSM3879997", "GSM3879998", "GSM3879999", "GSM3880000", "GSM3880001", "GSM3880002", "GSM3880003", "GSM3880004", "GSM3880005", "GSM3880006", "GSM3880007", "GSM3880008", "GSM3880009", "GSM3880010", "GSM3880011", "GSM3880012", "GSM3880013", "GSM3880014", "GSM3880015", "GSM3880016", "GSM3880017", "GSM3880018", "GSM3880019"], "sample_count": 276, "group_sizes": null, "group_sizes_basis": null, "platform": "15207", "taxon": "Homo sapiens", "title": "Longitudinal Blood Transcriptomic Changes Predict Lung Function Decline in Idiopathic Pulmonary Fibrosis", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE141259", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE141259", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM4200035", "GSM4200036", "GSM4200037", "GSM4200038", "GSM4200039", "GSM4200040", "GSM4200041", "GSM4200042", "GSM4200043", "GSM4200044", "GSM4200045", "GSM4200046", "GSM4200047", "GSM4200048", "GSM4200049", "GSM4200050", "GSM4200051", "GSM4200052", "GSM4200053", "GSM4200054", "GSM4200055", "GSM4200056", "GSM4200057", "GSM4200058", "GSM4200059", "GSM4200060", "GSM4200061", "GSM4200062", "GSM4200063", "GSM4200064", "GSM4200065", "GSM4200066", "GSM4200067", "GSM4200068", "GSM4200069", "GSM4200070", "GSM4200071", "GSM4200072", "GSM4200073", "GSM4200074", "GSM4200075", "GSM4200076", "GSM4200077", "GSM4200078", "GSM4200079", "GSM4200080", "GSM4200081", "GSM4200082", "GSM4200083", "GSM4200084", "GSM4200085", "GSM4200086", "GSM4200087", "GSM4200088", "GSM4200089", "GSM4200090", "GSM4200091", "GSM4200092", "GSM4200093", "GSM4200094"], "sample_count": 60, "group_sizes": null, "group_sizes_basis": null, "platform": "21103", "taxon": "Mus musculus", "title": "Longitudinal single-cell transcriptomics analysis of mouse lung upon bleomycin-induced injury", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE27957", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE27957", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM691362", "GSM691363", "GSM691364", "GSM691365", "GSM691366", "GSM691367", "GSM691368", "GSM691369", "GSM691370", "GSM691371", "GSM691372", "GSM691373", "GSM691374", "GSM691375", "GSM691376", "GSM691377", "GSM691378", "GSM691379", "GSM691380", "GSM691381", "GSM691382", "GSM691383", "GSM691384", "GSM691385", "GSM691386", "GSM691387", "GSM691388", "GSM691389", "GSM691390", "GSM691391", "GSM691392", "GSM691393", "GSM691394", "GSM691395", "GSM691396", "GSM691397", "GSM691398", "GSM691399", "GSM691400", "GSM691401", "GSM691402", "GSM691403", "GSM691404", "GSM691405", "GSM691406"], "sample_count": 45, "group_sizes": null, "group_sizes_basis": null, "platform": "5175", "taxon": "Homo sapiens", "title": "Peripheral Blood Mononuclear Cell Gene Expression Profiles May Predict Poor Outcome in Idiopathic Pulmonary Fibrosis [Affymetrix]", "resolution_checked_at": "2026-11-01T15:39:54Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE28042", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE28042", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM693750", "GSM693751", "GSM693752", "GSM693753", "GSM693754", "GSM693755", "GSM693756", "GSM693757", "GSM693758", "GSM693759", "GSM693760", "GSM693761", "GSM693762", "GSM693763", "GSM693764", "GSM693765", "GSM693766", "GSM693767", "GSM693768", "GSM693769", "GSM693770", "GSM693771", "GSM693772", "GSM693773", "GSM693774", "GSM693775", "GSM693776", "GSM693777", "GSM693778", "GSM693779", "GSM693780", "GSM693781", "GSM693782", "GSM693783", "GSM693784", "GSM693785", "GSM693786", "GSM693787", "GSM693788", "GSM693789", "GSM693790", "GSM693791", "GSM693792", "GSM693793", "GSM693794", "GSM693795", "GSM693796", "GSM693797", "GSM693798", "GSM693799", "GSM693800", "GSM693801", "GSM693802", "GSM693803", "GSM693804", "GSM693805", "GSM693806", "GSM693807", "GSM693808", "GSM693809", "GSM693810", "GSM693811", "GSM693812", "GSM693813", "GSM693814", "GSM693815", "GSM693816", "GSM693817", "GSM693818", "GSM693819", "GSM693820", "GSM693821", "GSM693822", "GSM693823", "GSM693824", "GSM698440", "GSM698441", "GSM698442", "GSM698443", "GSM698444", "GSM698445", "GSM698446", "GSM698447", "GSM698448", "GSM698449", "GSM698450", "GSM698451", "GSM698452", "GSM698453", "GSM698454", "GSM698455", "GSM698456", "GSM698457", "GSM698458"], "sample_count": 94, "group_sizes": null, "group_sizes_basis": null, "platform": "6480", "taxon": "Homo sapiens", "title": "Peripheral Blood Mononuclear Cell Gene Expression Profiles May Predict Poor Outcome in Idiopathic Pulmonary Fibrosis [Agilent]", "resolution_checked_at": "2026-11-01T15:39:54Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE32537", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE32537", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM806204", "GSM806205", "GSM806206", "GSM806207", "GSM806208", "GSM806209", "GSM806210", "GSM806211", "GSM806212", "GSM806213", "GSM806214", "GSM806215", "GSM806216", "GSM806217", "GSM806218", "GSM806219", "GSM806220", "GSM806221", "GSM806222", "GSM806223", "GSM806224", "GSM806225", "GSM806226", "GSM806227", "GSM806228", "GSM806229", "GSM806230", "GSM806231", "GSM806232", "GSM806233", "GSM806234", "GSM806235", "GSM806236", "GSM806237", "GSM806238", "GSM806239", "GSM806240", "GSM806241", "GSM806242", "GSM806243", "GSM806244", "GSM806245", "GSM806246", "GSM806247", "GSM806248", "GSM806249", "GSM806250", "GSM806251", "GSM806252", "GSM806253", "GSM806254", "GSM806255", "GSM806256", "GSM806257", "GSM806258", "GSM806259", "GSM806260", "GSM806261", "GSM806262", "GSM806263", "GSM806264", "GSM806265", "GSM806266", "GSM806267", "GSM806268", "GSM806269", "GSM806270", "GSM806271", "GSM806272", "GSM806273", "GSM806274", "GSM806275", "GSM806276", "GSM806277", "GSM806278", "GSM806279", "GSM806280", "GSM806281", "GSM806282", "GSM806283", "GSM806284", "GSM806285", "GSM806286", "GSM806287", "GSM806288", "GSM806289", "GSM806290", "GSM806291", "GSM806292", "GSM806293", "GSM806294", "GSM806295", "GSM806296", "GSM806297", "GSM806298", "GSM806299", "GSM806300", "GSM806301", "GSM806302", "GSM806303", "GSM806304", "GSM806305", "GSM806306", "GSM806307", "GSM806308", "GSM806309", "GSM806310", "GSM806311", "GSM806312", "GSM806313", "GSM806314", "GSM806315", "GSM806316", "GSM806317", "GSM806318", "GSM806319", "GSM806320", "GSM806321", "GSM806322", "GSM806323", "GSM806324", "GSM806325", "GSM806326", "GSM806327", "GSM806328", "GSM806329", "GSM806330", "GSM806331", "GSM806332", "GSM806333", "GSM806334", "GSM806335", "GSM806336", "GSM806337", "GSM806338", "GSM806339", "GSM806340", "GSM806341", "GSM806342", "GSM806343", "GSM806344", "GSM806345", "GSM806346", "GSM806347", "GSM806348", "GSM806349", "GSM806350", "GSM806351", "GSM806352", "GSM806353", "GSM806354", "GSM806355", "GSM806356", "GSM806357", "GSM806358", "GSM806359", "GSM806360", "GSM806361", "GSM806362", "GSM806363", "GSM806364", "GSM806365", "GSM806366", "GSM806367", "GSM806368", "GSM806369", "GSM806370", "GSM806371", "GSM806372", "GSM806373", "GSM806374", "GSM806375", "GSM806376", "GSM806377", "GSM806378", "GSM806379", "GSM806380", "GSM806381", "GSM806382", "GSM806383", "GSM806384", "GSM806385", "GSM806386", "GSM806387", "GSM806388", "GSM806389", "GSM806390", "GSM806391", "GSM806392", "GSM806393", "GSM806394", "GSM806395", "GSM806396", "GSM806397", "GSM806398", "GSM806399", "GSM806400", "GSM806401", "GSM806402", "GSM806403", "GSM806404", "GSM806405", "GSM806406", "GSM806407", "GSM806408", "GSM806409", "GSM806410", "GSM806411", "GSM806412", "GSM806413", "GSM806414", "GSM806415", "GSM806416", "GSM806417", "GSM806418", "GSM806419", "GSM806420"], "sample_count": 217, "group_sizes": null, "group_sizes_basis": null, "platform": "6244", "taxon": "Homo sapiens", "title": "Molecular phenotyping of the idiopathic interstitial pneumonias [mRNA]", "resolution_checked_at": "2026-11-01T15:39:54Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE33566", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE33566", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM829965", "GSM829966", "GSM829967", "GSM829968", "GSM829969", "GSM829970", "GSM829971", "GSM829972", "GSM829973", "GSM829974", "GSM829975", "GSM829976", "GSM829977", "GSM829978", "GSM829979", "GSM829980", "GSM829981", "GSM829982", "GSM829983", "GSM829984", "GSM829985", "GSM829986", "GSM829987", "GSM829988", "GSM829989", "GSM829990", "GSM829991", "GSM829992", "GSM829993", "GSM829994", "GSM829995", "GSM829996", "GSM829997", "GSM829998", "GSM829999", "GSM830000", "GSM830001", "GSM830002", "GSM830003", "GSM830004", "GSM830005", "GSM830006", "GSM830007", "GSM830008", "GSM830009", "GSM830010", "GSM830011", "GSM830012", "GSM830013", "GSM830014", "GSM830015", "GSM830016", "GSM830017", "GSM830018", "GSM830019", "GSM830020", "GSM830021", "GSM830022", "GSM830023", "GSM830024", "GSM830025", "GSM830026", "GSM830027", "GSM830028", "GSM830029", "GSM830030", "GSM830031", "GSM830032", "GSM830033", "GSM830034", "GSM830035", "GSM830036", "GSM830037", "GSM830038", "GSM830039", "GSM830040", "GSM830041", "GSM830042", "GSM830043", "GSM830044", "GSM830045", "GSM830046", "GSM830047", "GSM830048", "GSM830049", "GSM830050", "GSM830051", "GSM830052", "GSM830053", "GSM830054", "GSM830055", "GSM830056", "GSM830057", "GSM830058", "GSM830059", "GSM830060", "GSM830061", "GSM830062", "GSM830063", "GSM830064", "GSM830065", "GSM830066", "GSM830067", "GSM830068", "GSM830069", "GSM830070", "GSM830071", "GSM830072", "GSM830073", "GSM830074", "GSM830075", "GSM830076", "GSM830077", "GSM830078", "GSM830079", "GSM830080", "GSM830081", "GSM830082", "GSM830083", "GSM830084", "GSM830085", "GSM830086", "GSM830087"], "sample_count": 123, "group_sizes": null, "group_sizes_basis": null, "platform": "6480", "taxon": "Homo sapiens", "title": "The Peripheral Blood Transcriptome Predicts the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE38958", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE38958", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM952756", "GSM952757", "GSM952758", "GSM952759", "GSM952760", "GSM952761", "GSM952762", "GSM952763", "GSM952764", "GSM952765", "GSM952766", "GSM952767", "GSM952768", "GSM952769", "GSM952770", "GSM952771", "GSM952772", "GSM952773", "GSM952774", "GSM952775", "GSM952776", "GSM952777", "GSM952778", "GSM952779", "GSM952780", "GSM952781", "GSM952782", "GSM952783", "GSM952784", "GSM952785", "GSM952786", "GSM952787", "GSM952788", "GSM952789", "GSM952790", "GSM952791", "GSM952792", "GSM952793", "GSM952794", "GSM952795", "GSM952796", "GSM952797", "GSM952798", "GSM952799", "GSM952800", "GSM952801", "GSM952802", "GSM952803", "GSM952804", "GSM952805", "GSM952806", "GSM952807", "GSM952808", "GSM952809", "GSM952810", "GSM952811", "GSM952812", "GSM952813", "GSM952814", "GSM952815", "GSM952816", "GSM952817", "GSM952818", "GSM952819", "GSM952820", "GSM952821", "GSM952822", "GSM952823", "GSM952824", "GSM952825", "GSM952826", "GSM952827", "GSM952828", "GSM952829", "GSM952830", "GSM952831", "GSM952832", "GSM952833", "GSM952834", "GSM952835", "GSM952836", "GSM952837", "GSM952838", "GSM952839", "GSM952840", "GSM952841", "GSM952842", "GSM952843", "GSM952844", "GSM952845", "GSM952846", "GSM952847", "GSM952848", "GSM952849", "GSM952850", "GSM952851", "GSM952852", "GSM952853", "GSM952854", "GSM952855", "GSM952856", "GSM952857", "GSM952858", "GSM952859", "GSM952860", "GSM952861", "GSM952862", "GSM952863", "GSM952864", "GSM952865", "GSM952866", "GSM952867", "GSM952868", "GSM952869", "GSM952870"], "sample_count": 115, "group_sizes": null, "group_sizes_basis": null, "platform": "5175", "taxon": "Homo sapiens", "title": "Profiling of Gene Expression in Idiopathic Pulmonary Fibrosis", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE47460", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE47460", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM1149948", "GSM1149949", "GSM1149950", "GSM1149951", "GSM1149952", "GSM1149953", "GSM1149954", "GSM1149955", "GSM1149956", "GSM1149957", "GSM1149958", "GSM1149959", "GSM1149960", "GSM1149961", "GSM1149962", "GSM1149963", "GSM1149964", "GSM1149965", "GSM1149966", "GSM1149967", "GSM1149968", "GSM1149969", "GSM1149970", "GSM1149971", "GSM1149972", "GSM1149973", "GSM1149974", "GSM1149975", "GSM1149976", "GSM1149977", "GSM1149978", "GSM1149979", "GSM1149980", "GSM1149981", "GSM1149982", "GSM1149983", "GSM1149984", "GSM1149985", "GSM1149986", "GSM1149987", "GSM1149988", "GSM1149989", "GSM1149990", "GSM1149991", "GSM1149992", "GSM1149993", "GSM1149994", "GSM1149995", "GSM1149996", "GSM1149997", "GSM1149998", "GSM1149999", "GSM1150000", "GSM1150001", "GSM1150002", "GSM1150003", "GSM1150004", "GSM1150005", "GSM1150006", "GSM1150007", "GSM1150008", "GSM1150009", "GSM1150010", "GSM1150011", "GSM1150012", "GSM1150013", "GSM1150014", "GSM1150015", "GSM1150016", "GSM1150017", "GSM1150018", "GSM1150019", "GSM1150020", "GSM1150021", "GSM1150022", "GSM1150023", "GSM1150024", "GSM1150025", "GSM1150026", "GSM1150027", "GSM1150028", "GSM1150029", "GSM1150030", "GSM1150031", "GSM1150032", "GSM1150033", "GSM1150034", "GSM1150035", "GSM1150036", "GSM1150037", "GSM1150038", "GSM1150039", "GSM1150040", "GSM1150041", "GSM1150042", "GSM1150043", "GSM1150044", "GSM1150045", "GSM1150046", "GSM1150047", "GSM1150048", "GSM1150049", "GSM1150050", "GSM1150051", "GSM1150052", "GSM1150053", "GSM1150054", "GSM1150055", "GSM1150056", "GSM1150057", "GSM1150058", "GSM1150059", "GSM1150060", "GSM1150061", "GSM1150062", "GSM1150063", "GSM1150064", "GSM1150065", "GSM1150066", "GSM1150067", "GSM1150068", "GSM1150069", "GSM1150070", "GSM1150071", "GSM1150072", "GSM1150073", "GSM1150074", "GSM1150075", "GSM1150076", "GSM1150077", "GSM1150078", "GSM1150079", "GSM1150080", "GSM1150081", "GSM1150082", "GSM1150083", "GSM1150084", "GSM1150085", "GSM1150086", "GSM1150087", "GSM1150088", "GSM1150089", "GSM1150090", "GSM1150091", "GSM1150092", "GSM1150093", "GSM1150094", "GSM1150095", "GSM1150096", "GSM1150097", "GSM1150098", "GSM1150099", "GSM1150100", "GSM1150101", "GSM1150102", "GSM1150103", "GSM1150104", "GSM1150105", "GSM1150106", "GSM1150107", "GSM1150108", "GSM1150109", "GSM1150110", "GSM1150111", "GSM1150112", "GSM1150113", "GSM1150114", "GSM1150115", "GSM1150116", "GSM1150117", "GSM1150118", "GSM1150119", "GSM1150120", "GSM1150121", "GSM1150122", "GSM1150123", "GSM1150124", "GSM1150125", "GSM1150126", "GSM1150127", "GSM1150128", "GSM1150129", "GSM1150130", "GSM1150131", "GSM1150132", "GSM1150133", "GSM1150134", "GSM1150135", "GSM1150136", "GSM1150137", "GSM1150138", "GSM1150139", "GSM1150140", "GSM1150141", "GSM1150142", "GSM1150143", "GSM1150144", "GSM1150145", "GSM1150146", "GSM1150147", "GSM1150148", "GSM1150149", "GSM1150150", "GSM1150151", "GSM1150152", "GSM1150153", "GSM1150154", "GSM1150155", "GSM1150156", "GSM1150157", "GSM1150158", "GSM1150159", "GSM1150160", "GSM1150161", "GSM1150162", "GSM1150163", "GSM1150164", "GSM1150165", "GSM1150166", "GSM1150167", "GSM1150168", "GSM1150169", "GSM1150170", "GSM1150171", "GSM1150172", "GSM1150173", "GSM1150174", "GSM1150175", "GSM1150176", "GSM1150177", "GSM1150178", "GSM1150179", "GSM1150180", "GSM1150181", "GSM1150182", "GSM1150183", "GSM1150184", "GSM1150185", "GSM1150186", "GSM1150187", "GSM1150188", "GSM1150189", "GSM1150190", "GSM1150191", "GSM1150192", "GSM1150193", "GSM1150194", "GSM1150195", "GSM1150196", "GSM1150197", "GSM1150198", "GSM1150199", "GSM1150200", "GSM1150201", "GSM1150202", "GSM1150203", "GSM1150204", "GSM1150205", "GSM1150206", "GSM1150207", "GSM1150208", "GSM1150209", "GSM1150210", "GSM1150211", "GSM1150212", "GSM1150213", "GSM1150214", "GSM1150215", "GSM1150216", "GSM1150217", "GSM1150218", "GSM1150219", "GSM1150220", "GSM1150221", "GSM1150222", "GSM1150223", "GSM1150224", "GSM1150225", "GSM1150226", "GSM1150227", "GSM1150228", "GSM1150229", "GSM1150230", "GSM1150231", "GSM1150232", "GSM1150233", "GSM1150234", "GSM1150235", "GSM1150236", "GSM1150237", "GSM1150238", "GSM1150239", "GSM1150240", "GSM1150241", "GSM1150242", "GSM1150243", "GSM1150244", "GSM1150245", "GSM1150246", "GSM1150247", "GSM1150248", "GSM1150249", "GSM1150250", "GSM1150251", "GSM1150252", "GSM1150253", "GSM1150254", "GSM1150255", "GSM1150256", "GSM1150257", "GSM1150258", "GSM1150259", "GSM1150260", "GSM1150261", "GSM1150262", "GSM1150263", "GSM1150264", "GSM1150265", "GSM1150266", "GSM1150267", "GSM1150268", "GSM1150269", "GSM1150270", "GSM1150271", "GSM1150272", "GSM1150273", "GSM1150274", "GSM1150275", "GSM1150276", "GSM1150277", "GSM1150278", "GSM1150279", "GSM1150280", "GSM1150281", "GSM1150282", "GSM1150283", "GSM1150284", "GSM1150285", "GSM1150286", "GSM1150287", "GSM1150288", "GSM1150289", "GSM1150290", "GSM1150291", "GSM1150292", "GSM1150293", "GSM1150294", "GSM1150295", "GSM1150296", "GSM1150297", "GSM1150298", "GSM1150299", "GSM1150300", "GSM1150301", "GSM1150302", "GSM1150303", "GSM1150304", "GSM1150305", "GSM1150306", "GSM1150307", "GSM1150308", "GSM1150309", "GSM1150310", "GSM1150311", "GSM1150312", "GSM1150313", "GSM1150314", "GSM1150315", "GSM1150316", "GSM1150317", "GSM1150318", "GSM1150319", "GSM1150321", "GSM1150331", "GSM1150332", "GSM1150334", "GSM1150336", "GSM1150338", "GSM1150339", "GSM1150341", "GSM1150343", "GSM1150344", "GSM1150346", "GSM1150347", "GSM1150349", "GSM1150351", "GSM1150352", "GSM1150353", "GSM1150354", "GSM1150355", "GSM1150356", "GSM1150357", "GSM1150358", "GSM1150359", "GSM1150360", "GSM1150361", "GSM1150362", "GSM1150363", "GSM1150364", "GSM1150365", "GSM1150366", "GSM1150367", "GSM1150368", "GSM1150369", "GSM1150370", "GSM1150371", "GSM1150372", "GSM1150373", "GSM1150374", "GSM1150375", "GSM1150376", "GSM1150377", "GSM1150378", "GSM1150379", "GSM1150380", "GSM1150381", "GSM1150382", "GSM1150383", "GSM1150384", "GSM1150385", "GSM1150386", "GSM1150387", "GSM1150388", "GSM1150389", "GSM1150390", "GSM1150391", "GSM1150392", "GSM1150393", "GSM1150394", "GSM1150395", "GSM1150396", "GSM1150397", "GSM1150398", "GSM1150399", "GSM1150400", "GSM1150401", "GSM1150402", "GSM1150403", "GSM1150404", "GSM1150405", "GSM1150406", "GSM1150407", "GSM1150408", "GSM1150409", "GSM1150410", "GSM1150411", "GSM1150412", "GSM1150413", "GSM1150414", "GSM1150415", "GSM1150416", "GSM1150417", "GSM1150418", "GSM1150419", "GSM1150420", "GSM1150421", "GSM1150422", "GSM1150423", "GSM1150424", "GSM1150425", "GSM1150426", "GSM1150427", "GSM1150428", "GSM1150429", "GSM1150430", "GSM1150431", "GSM1150432", "GSM1150433", "GSM1150434", "GSM1150435", "GSM1150436", "GSM1150437", "GSM1150438", "GSM1150439", "GSM1150440", "GSM1150441", "GSM1150442", "GSM1150443", "GSM1150444", "GSM1150445", "GSM1150446", "GSM1150447", "GSM1150448", "GSM1150449", "GSM1150450", "GSM1150451", "GSM1150452", "GSM1150453", "GSM1150454", "GSM1150455", "GSM1150456", "GSM1150457", "GSM1150458", "GSM1150459", "GSM1150460", "GSM1150461", "GSM1150462", "GSM1150463", "GSM1150464", "GSM1150465", "GSM1150466", "GSM1150467", "GSM1150468", "GSM1150469", "GSM1150470", "GSM1150471", "GSM1150472", "GSM1150473", "GSM1150474", "GSM1150475", "GSM1150476", "GSM1150477", "GSM1150478", "GSM1150479", "GSM1150480", "GSM1150481", "GSM1150482", "GSM1150483", "GSM1150484", "GSM1150485", "GSM1150486", "GSM1150487", "GSM1150488", "GSM1150489", "GSM1150490", "GSM1150491", "GSM1150492", "GSM1150493", "GSM1150494", "GSM1150495", "GSM1150496", "GSM1150497", "GSM1150498", "GSM1150499", "GSM1150500", "GSM1150501", "GSM1150502", "GSM1150503", "GSM1150504", "GSM1150505", "GSM1150506", "GSM1150507", "GSM1150508", "GSM1150509", "GSM1150510", "GSM1150511", "GSM1150512", "GSM1150513", "GSM1150514", "GSM1150515", "GSM1150516", "GSM1150517", "GSM1150518", "GSM1150519", "GSM1150520", "GSM1150521", "GSM1150522", "GSM1150523", "GSM1150524", "GSM1150525", "GSM1150526", "GSM1150527", "GSM1150528", "GSM1150529", "GSM1150530", "GSM1150531", "GSM1150532", "GSM1150533", "GSM1150534", "GSM1150535", "GSM1150536", "GSM1150537", "GSM1150538", "GSM1150539", "GSM1150540", "GSM1150541", "GSM1150542", "GSM1150543", "GSM1150544", "GSM1150545", "GSM1150546", "GSM1150547"], "sample_count": 582, "group_sizes": null, "group_sizes_basis": null, "platform": "6480;14550", "taxon": "Homo sapiens", "title": "Gene expression profiling of chronic lung disease for the Lung Genomics Research Consortium", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE70866", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE70866", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM1820719", "GSM1820720", "GSM1820721", "GSM1820722", "GSM1820723", "GSM1820724", "GSM1820725", "GSM1820726", "GSM1820727", "GSM1820728", "GSM1820729", "GSM1820730", "GSM1820731", "GSM1820732", "GSM1820733", "GSM1820734", "GSM1820735", "GSM1820736", "GSM1820737", "GSM1820738", "GSM1820739", "GSM1820740", "GSM1820741", "GSM1820742", "GSM1820743", "GSM1820744", "GSM1820745", "GSM1820746", "GSM1820747", "GSM1820748", "GSM1820749", "GSM1820750", "GSM1820751", "GSM1820752", "GSM1820753", "GSM1820754", "GSM1820755", "GSM1820756", "GSM1820757", "GSM1820758", "GSM1820759", "GSM1820760", "GSM1820761", "GSM1820762", "GSM1820763", "GSM1820764", "GSM1820765", "GSM1820766", "GSM1820767", "GSM1820768", "GSM1820769", "GSM1820770", "GSM1820771", "GSM1820772", "GSM1820773", "GSM1820774", "GSM1820775", "GSM1820776", "GSM1820777", "GSM1820778", "GSM1820779", "GSM1820780", "GSM1820781", "GSM1820782", "GSM1820783", "GSM1820784", "GSM1820785", "GSM1820786", "GSM1820787", "GSM1820788", "GSM1820789", "GSM1820790", "GSM1820791", "GSM1820792", "GSM1820793", "GSM1820794", "GSM1820795", "GSM1820796", "GSM1820797", "GSM1820798", "GSM1820799", "GSM1820800", "GSM1820801", "GSM1820802", "GSM1820803", "GSM1820804", "GSM1820805", "GSM1820806", "GSM1820807", "GSM1820808", "GSM1820809", "GSM1820810", "GSM1820811", "GSM1820812", "GSM1820813", "GSM1820814", "GSM1820815", "GSM1820816", "GSM1820817", "GSM1820818", "GSM1820819", "GSM1820820", "GSM1820821", "GSM1820822", "GSM1820823", "GSM1820824", "GSM1820825", "GSM1820826", "GSM1820827", "GSM1820828", "GSM1820829", "GSM1820830", "GSM1820831", "GSM1820832", "GSM1820833", "GSM1820834", "GSM1820835", "GSM1820836", "GSM1820837", "GSM1820838", "GSM1820839", "GSM1820840", "GSM1820841", "GSM1820842", "GSM1820843", "GSM1820844", "GSM1820845", "GSM1820846", "GSM1820847", "GSM1820848", "GSM1820849", "GSM1820850", "GSM1820851", "GSM1820852", "GSM1820853", "GSM1820854", "GSM1820855", "GSM1820856", "GSM1820857", "GSM1820858", "GSM1820859", "GSM1820860", "GSM1820861", "GSM1820862", "GSM1820863", "GSM1820864", "GSM1820865", "GSM1820866", "GSM1820867", "GSM1820868", "GSM1820869", "GSM1820870", "GSM1820871", "GSM1820872", "GSM1820873", "GSM1820874", "GSM1820875", "GSM1820876", "GSM1820877", "GSM1820878", "GSM1820879", "GSM1820880", "GSM1820881", "GSM1820882", "GSM1820883", "GSM1820884", "GSM1820885", "GSM1820886", "GSM1820887", "GSM1820888", "GSM1820889", "GSM1820890", "GSM1820891", "GSM1820892", "GSM1820893", "GSM1820894", "GSM1820895", "GSM1820896", "GSM1820897", "GSM1820898", "GSM1820899", "GSM1820900", "GSM1820901", "GSM1820902", "GSM1820903", "GSM1820904", "GSM1820905", "GSM1820906", "GSM1820907", "GSM1820908", "GSM1820909", "GSM1820910", "GSM1820911", "GSM1820912", "GSM1820913", "GSM1820914"], "sample_count": 196, "group_sizes": null, "group_sizes_basis": null, "platform": "17077;14550", "taxon": "Homo sapiens", "title": "BAL cell gene expression is predictive of Mortality in Idiopathic Pulmonary Fibrosis and enriched for Genes of Airway Basal Cells (II)", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE93606", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE93606", "version": null, "note": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 .", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM2458563", "GSM2458564", "GSM2458565", "GSM2458566", "GSM2458567", "GSM2458568", "GSM2458569", "GSM2458570", "GSM2458571", "GSM2458572", "GSM2458573", "GSM2458574", "GSM2458575", "GSM2458576", "GSM2458577", "GSM2458578", "GSM2458579", "GSM2458580", "GSM2458581", "GSM2458582", "GSM2458583", "GSM2458584", "GSM2458585", "GSM2458586", "GSM2458587", "GSM2458588", "GSM2458589", "GSM2458590", "GSM2458591", "GSM2458592", "GSM2458593", "GSM2458594", "GSM2458595", "GSM2458596", "GSM2458597", "GSM2458598", "GSM2458599", "GSM2458600", "GSM2458601", "GSM2458602", "GSM2458603", "GSM2458604", "GSM2458605", "GSM2458606", "GSM2458607", "GSM2458608", "GSM2458609", "GSM2458610", "GSM2458611", "GSM2458612", "GSM2458613", "GSM2458614", "GSM2458615", "GSM2458616", "GSM2458617", "GSM2458618", "GSM2458619", "GSM2458620", "GSM2458621", "GSM2458622", "GSM2458623", "GSM2458624", "GSM2458625", "GSM2458626", "GSM2458627", "GSM2458628", "GSM2458629", "GSM2458630", "GSM2458631", "GSM2458632", "GSM2458633", "GSM2458634", "GSM2458635", "GSM2458636", "GSM2458637", "GSM2458638", "GSM2458639", "GSM2458640", "GSM2458641", "GSM2458642", "GSM2458643", "GSM2458644", "GSM2458645", "GSM2458646", "GSM2458647", "GSM2458648", "GSM2458649", "GSM2458650", "GSM2458651", "GSM2458652", "GSM2458653", "GSM2458654", "GSM2458655", "GSM2458656", "GSM2458657", "GSM2458658", "GSM2458659", "GSM2458660", "GSM2458661", "GSM2458662", "GSM2458663", "GSM2458664", "GSM2458665", "GSM2458666", "GSM2458667", "GSM2458668", "GSM2458669", "GSM2458670", "GSM2458671", "GSM2458672", "GSM2458673", "GSM2458674", "GSM2458675", "GSM2458676", "GSM2458677", "GSM2458678", "GSM2458679", "GSM2458680", "GSM2458681", "GSM2458682", "GSM2458683", "GSM2458684", "GSM2458685", "GSM2458686", "GSM2458687", "GSM2458688", "GSM2458689", "GSM2458690", "GSM2458691", "GSM2458692", 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"label": "Computational analysis platform", "assay_families": ["meta_analysis", "machine_learning", "survival_analysis", "statistical_regression", "pca", "molecular_docking", "network_analysis", "differential_expression", "gwas"], "availability_state": "owned", "tier_unlocked": "R1", "candidate": "Automated Assays Laravel application and simulated adapters"}], "gaps": []}, "readiness": {"state": "complete", "tier": "R1", "blocking_axis": "none", "blocked_on": "nothing:replicable_now", "axes": {"method": {"tier": "R1", "expressible": true, "required_operations": ["glm_logit_fit"], "missing_operations": [], "basis": "The paper names the method it used and the corpus's method extractor maps it onto the DSL catalogue: logistic."}, "capability": {"tier": "R1", "capability_id": "capability:computational_analysis", "availability_state": "owned", "basis": "The computational analysis is owned. The physical bench the paper used is not, so a physical validation cannot be run here."}, "data": {"tier": "R1", "reachable": true, "accessions": ["GSE32537", "GSE47460", "GSE110147", "GSE141259", "GSE93606", "GSE27957", "GSE28042", "GSE38958", "GSE132607", "GSE33566", "GSE70866"], "resolved_accessions": ["GSE32537", "GSE47460", "GSE110147", "GSE141259", "GSE93606", "GSE27957", "GSE28042", "GSE38958", "GSE132607", "GSE33566", "GSE70866"], "statements": ["Publicly available datasets were analyzed in this study. This data can be found here: GSE32537 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32537), GSE47460 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47460), GSE110147 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110147), GSE141259 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141259), GSE93606 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93606, GSE27957 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27957), GSE28042 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28042), GSE38958 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38958), GSE132607 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132607), GSE33566 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33566), GSE70866 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70866). The annotated gene set file used in ssGSEA were available in Supplementary Material 2 ."], "basis": "The paper names GSE32537, GSE47460, GSE110147, GSE141259, GSE93606, GSE27957, GSE28042, GSE38958, GSE132607, GSE33566, GSE70866 in Gene Expression Omnibus (GEO) and the accession resolves in the repository. No dataset was downloaded and no licence was read."}}, "can_run": {"dsl_operations": ["glm_logit_fit"], "assets": ["source:pmid:34880861", "data:geo:GSE110147"], "steps": ["run_analysis"]}, "must_build": {"dsl_operations": [], "converters": [], "readers": [], "capabilities": [], "data_gaps": ["data:geo:GSE110147"]}, "gaps": []}, "review": {"state": "partial", "machine_critique": {"kind": "extraction_review", "reader": {"model": "MiniMax-M3.1-Flash", "provider": "minimax", "provider_family": "minimax", "read_at": "2026-11-01T17:10:40Z", "independence": "single_reader"}, "evidence_check": {"method": "verbatim", "availability": "verbatim"}, "calls": 5, "usage": {"prompt_tokens": 15620, "completion_tokens": 3968, "cached_tokens": 128}}, "human_critique": null, "stages": [{"id": "extraction", "state": "complete", "reader": "MiniMax-M3.1-Flash", "provider": "minimax"}], "gaps": ["review.independent_reader", "review.machine_critique", "review.human_critique"]}, "execution": {"state": "absent", "status": "not_run", "mode": null, "runs": [], "gaps": ["execution.not_run"]}, "provenance": {"entities": [{"id": "pmid:34880861", "type": "paper", "label": "pmid:34880861"}, {"id": "source:pmid:34880861", "type": "manuscript", "label": "PMID 34880861 full text"}, {"id": "data:geo:GSE110147", "type": "dataset", "label": "GEO GSE110147"}], "activities": [{"id": "activity-reading-sci-2026-11-01", "type": "classification", "used": [{"id": "pmid:34880861", "type": "paper", "label": "pmid:34880861"}, {"id": "source:pmid:34880861", "type": "manuscript", "label": "PMID 34880861 full text"}, {"id": "data:geo:GSE110147", "type": "dataset", "label": "GEO GSE110147"}], "agent": "agent:corpus-assay-engine"}, {"id": "activity-read-34880861", "type": "extraction", "used": ["source:pmid:34880861"], "agent": "agent:minimax-reader"}, {"id": "activity-resolve-GSE110147", "type": "accession_resolution", "used": ["data:geo:GSE110147"], "agent": "agent:corpus-assay-engine"}], "agents": [{"id": "agent:corpus-assay-engine", "type": "software", "label": "Corpus assay engine"}, {"id": "agent:minimax-reader", "type": "software", "label": "MiniMax literature reader"}], "source_run_id": "reading-sci-2026-11-01", "dsl_catalogue_fingerprint": "343fb30756ba6ec3", "capability_table_fingerprint": "2cb3e42f047d2ecf", "snapshot_id": "ba34b49490d9bfaf"}, "lineage": {"parent_id": "pmid:34880861", "parent_hash": "sha256:3dbfd914fddd05a7943a8f2cf5912498bb2aa43d174eecce3b7379703daf246b", "fork_of": null, "generation": 4}, "gaps": ["asset:data:geo:GSE110147 licence not read", "asset:data:geo:GSE110147 not downloaded", "asset:data:geo:GSE132607 licence not read", "asset:data:geo:GSE132607 not downloaded", "asset:data:geo:GSE141259 licence not read", "asset:data:geo:GSE141259 not downloaded", "asset:data:geo:GSE27957 licence not read", "asset:data:geo:GSE27957 not downloaded", "asset:data:geo:GSE28042 licence not read", "asset:data:geo:GSE28042 not downloaded", "asset:data:geo:GSE32537 licence not read", "asset:data:geo:GSE32537 not downloaded", "asset:data:geo:GSE33566 licence not read", "asset:data:geo:GSE33566 not downloaded", "asset:data:geo:GSE38958 licence not read", "asset:data:geo:GSE38958 not downloaded", "asset:data:geo:GSE47460 licence not read", "asset:data:geo:GSE47460 not downloaded", "asset:data:geo:GSE70866 licence not read", "asset:data:geo:GSE70866 not downloaded", "asset:data:geo:GSE93606 licence not read", "asset:data:geo:GSE93606 not downloaded", "execution.not_run", "method.reader_differs_from_extractor", "review.human_critique", "review.independent_reader", "review.machine_critique"], "assays": [{"role": "data_generation", "definition_id": "scrna_seq", "definition_version": "99e1195c7d6f", "definition_digest": null, "required_operations": [], "support_state": "unsupported", "source_hashes": {"assay_lexicon": "99e1195c7d6f"}, "confidence": 0.99, "evidence": ["Materials and Methods Analysis of scRNA-seq Data The computational analysis of the GSE14", "nsform () function was used to normalize the scRNA-seq data. Principal component analysis (PCA) was", "ine in FVC >10% over six months period). The scRNA-seq Data Analysis of CD247 According to the Lung", "ells and NK cells in the human lung based on scRNA-seq data (37) ( Supplementary Figure 5A ). In th"], "order_basis": "paper_text_order:1995", "id": "assay:1"}, {"role": "data_generation", "definition_id": "animal_model", "definition_version": "99e1195c7d6f", "definition_digest": null, "required_operations": [], "support_state": "partial", "source_hashes": {"assay_lexicon": "99e1195c7d6f"}, "confidence": 0.99, "evidence": ["A-seq data (37) ( Supplementary Figure 5A ). In the mouse lung, Cd247 is also mainly expressed by the", "ata (37) ( Supplementary Figure 5A ). In the mouse lung, Cd247 is also mainly expressed by the", "tabase (https://www.lungmap.net/), (B–D) the mouse lung (GSE141259 dataset).Click here for addi"], "order_basis": "paper_text_order:6417", "id": "assay:2"}, {"role": "analysis", "definition_id": "regression_modelling", "definition_version": "f2132e96ae6c7a4e", "definition_digest": null, "required_operations": ["glm_logit_fit"], "support_state": "supported", "source_hashes": {"dsl_catalogue": "f2132e96ae6c7a4e"}, "confidence": 1.0, "evidence": ["CD247 was identified as the hub gene associated with percent predicted diffusion capacity of the lung for carbon monoxide (Dlco% predicted) and prognosis according to Pearson correlation, logistic regression, and survival analysis."], "order_basis": "consumes_earlier_output", "id": "assay:3"}]}