← All .science files
pmid:34938355
Recognition of the Possible miRNA-mRNA Controlling Network in Stroke by Bioinformatics Examination.
Wei Li · Jian Li · Yong Yang
Computational and mathematical methods in medicine · 2021 doi:10.1155/2021/6745282
Paper
complete
Experiment
partial
Data
partial
Analysis
partial
Execution
absent
Execution evidence has not yet been added to this .science file. Explore its methods, data and open questions to plan the next step.
Record details sci_version · id · kind · revision · content_hash · schema · created_at · updated_at · generator
paper object · 10 fields
authors array · 3 items
claims array · 3 items
[0] object · 6 fields
[1] object · 6 fields
gaps array · 0 items
experiment object · 8 fields
steps array · 3 items
[0] object · 13 fields
parameters object · 0 fields
inputs array · 1 item
outputs array · 1 item
instruments array · 0 items
reagents array · 0 items
[1] object · 13 fields
parameters object · 0 fields
inputs array · 1 item
outputs array · 1 item
instruments array · 0 items
reagents array · 0 items
[2] object · 13 fields
parameters object · 0 fields
inputs array · 1 item
outputs array · 1 item
instruments array · 0 items
reagents array · 0 items
materials array · 0 items
instruments array · 0 items
reagents array · 0 items
conditions object · 0 fields
gaps array · 1 item
data object · 3 fields
assets array · 4 items
[0] object · 15 fields
structure object · 4 fields
[1] object · 15 fields
structure object · 15 fields
sample_accessions array · 1785 items
[2] object · 15 fields
structure object · 15 fields
sample_accessions array · 92 items
[3] object · 15 fields
structure object · 15 fields
sample_accessions array · 9 items
gaps array · 6 items
analysis object · 4 fields
methods array · 4 items
[0] object · 10 fields
dsl_operations array · 0 items
missing_operations array · 1 item
parameters object · 0 fields
data_shapes array · 1 item
[1] object · 10 fields
dsl_operations array · 4 items
missing_operations array · 0 items
parameters object · 0 fields
data_shapes array · 1 item
[2] object · 10 fields
dsl_operations array · 3 items
missing_operations array · 0 items
parameters object · 0 fields
data_shapes array · 1 item
[3] object · 10 fields
dsl_operations array · 1 item
missing_operations array · 0 items
parameters object · 0 fields
data_shapes array · 1 item
targets array · 0 items
gaps array · 1 item
capability object · 3 fields
requirements array · 1 item
[0] object · 6 fields
assay_families array · 9 items
gaps array · 0 items
readiness object · 8 fields
axes object · 3 fields
method object · 5 fields
required_operations array · 0 items
missing_operations array · 1 item
capability object · 4 fields
data object · 6 fields
accessions array · 3 items
resolved_accessions array · 3 items
statements array · 1 item
can_run object · 3 fields
dsl_operations array · 0 items
assets array · 2 items
steps array · 0 items
must_build object · 5 fields
dsl_operations array · 1 item
[0] object · 3 fields
converters array · 0 items
readers array · 0 items
capabilities array · 0 items
data_gaps array · 1 item
gaps array · 0 items
review object · 5 fields
machine_critique object · 5 fields
reader object · 5 fields
evidence_check object · 2 fields
usage object · 3 fields
stages array · 1 item
[0] object · 4 fields
gaps array · 3 items
provenance object · 7 fields
entities array · 3 items
activities array · 3 items
[0] object · 4 fields
used array · 3 items
[0] object · 3 fields
[1] object · 3 fields
[2] object · 3 fields
[1] object · 4 fields
agents array · 2 items
lineage object · 4 fields
gaps array · 12 items
assays array · 2 items
[0] object · 11 fields
required_operations array · 0 items
source_hashes object · 1 field
evidence array · 1 item
[1] object · 11 fields
required_operations array · 0 items
source_hashes object · 1 field
evidence array · 1 item
Complete file
{"sci_version": "1.2", "schema": "https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json", "id": "pmid:34938355", "kind": "science-record", "revision": 5, "content_hash": "sha256:2e07383c72a6d287e9614508cfca67c36c432944155cb0d22521f403c2b7b4a5", "created_at": "2026-11-01T17:36:39Z", "updated_at": "2026-11-01T22:48:06Z", "generator": {"name": "corpus-assay-engine", "run_id": "reading-sci-2026-11-01"}, "paper": {"state": "complete", "title": "Recognition of the Possible miRNA-mRNA Controlling Network in Stroke by Bioinformatics Examination.", "doi": "10.1155/2021/6745282", "pmid": "34938355", "authors": ["Wei Li", "Jian Li", "Yong Yang"], "journal": "Computational and mathematical methods in medicine", "year": 2021, "abstract": "BACKGROUND: Based on the latest research of WHO, it has been revealed that more than 15 million people suffer from stroke every year worldwide. Of these 15 million people, 6 million succumb to death, and 5 million get permanently disabled. This is the prime reason for the substantial economic burden on all parts of the world.\nMETHODS: These data have been obtained from the GEO database, and the GEO2R tool was used to find out the differentially expressed miRNAs (DEMs) between the stroke and normal patients' blood. FunRich and miRNet were considered to find potential upstream transcription factors and downstream target genes of candidate EMRs. Next, we use GO annotation and KEGG pathway enrichment. Target genes were analyzed with the help of the R software. Then, the STRING database and Cytoscape software were used to conduct PPI and DEM-hub gene networks. Finally, GSE58294 was used to estimate the hub gene expressions.\nRESULTS: Six DEMs in total were selected out from GSE95204 and GSE117064 datasets. 663 DEMs' target genes were predicted, and NRF1, EGR1, MYC, YY1, E2F1, SP4, and SP1 were predicted as an upstream transcription factor for DEMs' target genes. Target genes of DEMs were primarily augmented in the PI3K-Akt signaling pathway and p53 signaling pathway. The network construction of DEM hygiene is potentially modulated by hsa-miR-3591-5p, hsa-miR-548as-3p, hsa-miR-206, and hsa-miR-4503 hub genes which were found among the top 10 of the hub genes. Among the top 10 hub genes, justification of CTNNB1, PTEN, ESR1, CCND1, KRAS, AKT1, CCND2, CDKN1B, and MYCN was constant with that in the GSE58294 dataset.\nCONCLUSION: In summary, our research first constructs the miRNA-mRNA network in stroke, which probably renders an awakening purview into the pathogenesis and cure of stroke.", "claims": [{"id": "claim-method", "statement": "Student's t-test and one-way ANOVA were used to compare the means of two or more groups. The Cox proportional-hazards model was used for multivariate analyses.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:34938355", "locator": "sections[10] \"2.8. Statistical Analyses\" paragraph 2", "quote": "Student's t-test and one-way ANOVA were used to compare the means of two or more groups. The Cox proportional-hazards model was used for multivariate analyses."}], "state": "complete"}, {"id": "claim-data-access", "statement": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:34938355", "locator": "sections[19] \"Data Availability\" paragraph 2", "quote": "Data supporting the results of the study can be available by emailing the first author or corresponding author."}], "state": "complete"}, {"id": "claim-target-result", "statement": "Six DEMs in total were selected out from GSE95204 and GSE117064 datasets.", "kind": "qualitative", "target": null, "evidence": [{"asset": "source:pmid:34938355", "locator": "sections[0] \"Abstract\" paragraph 3", "quote": "Six DEMs in total were selected out from GSE95204 and GSE117064 datasets."}], "state": "complete"}], "gaps": []}, "experiment": {"state": "partial", "objective": "Six DEMs in total were selected out from GSE95204 and GSE117064 datasets.", "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The claim, method and evidence span published with the source article.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:34938355"], "outputs": ["the published estimate and its evidence"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the source data from the named repository", "kind": "data-preparation", "state": "complete", "blocked_on": null, "description": "The GEO series accession resolves and its sample accessions are listed. This lane did not download the dataset or read its licence.", "duration_hours": null, "parameters": {}, "inputs": ["data:geo:GSE117064"], "outputs": ["the source data with its repository provenance"], "instruments": [], "reagents": []}, {"id": "run_analysis", "order": 3, "name": "Run the published analysis", "kind": "analysis", "state": "blocked", "blocked_on": "method:student_t", "description": "Apply the paper's statistical method to the resolved series and compare the result with the published target.", "duration_hours": null, "parameters": {}, "inputs": ["data:geo:GSE117064"], "outputs": ["the replicated result and its comparison"], "instruments": [], "reagents": []}], "materials": [], "instruments": [], "reagents": [], "conditions": {}, "gaps": ["step:run_analysis blocked on method:student_t"]}, "data": {"state": "partial", "assets": [{"id": "source:pmid:34938355", "role": "manuscript", "format": "xml", "media_type": "application/xml", "uri": "https://doi.org/10.1155/2021/6745282", "sha256": "sha256:b092cf89648fa6b5b63bcdf2fea257bb9be4d5d92eb7de2c2c6947d69831d7da", "bytes": 19860, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "10.1155/2021/6745282", "version": null, "note": "Full article fetched from PMC; the checksum covers the rendered section body, not the original XML bytes.", "structure": {"pmcid": "PMC8687781", "source": "europe_pmc_fulltext", "coverage": "whole_body_without_references", "text_hash_scope": "rendered_section_body"}}, {"id": "data:geo:GSE117064", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117064", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE117064", "version": null, "note": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM3268083", "GSM3268084", "GSM3268085", "GSM3268086", "GSM3268087", "GSM3268088", "GSM3268089", "GSM3268090", "GSM3268091", "GSM3268092", "GSM3268093", "GSM3268094", "GSM3268095", "GSM3268096", "GSM3268097", "GSM3268098", "GSM3268099", "GSM3268100", "GSM3268101", "GSM3268102", "GSM3268103", "GSM3268104", "GSM3268105", "GSM3268106", "GSM3268107", "GSM3268108", "GSM3268109", "GSM3268110", "GSM3268111", "GSM3268112", "GSM3268113", "GSM3268114", "GSM3268115", "GSM3268116", "GSM3268117", "GSM3268118", "GSM3268119", "GSM3268120", "GSM3268121", "GSM3268122", "GSM3268123", "GSM3268124", "GSM3268125", "GSM3268126", "GSM3268127", "GSM3268128", "GSM3268129", "GSM3268130", "GSM3268131", "GSM3268132", "GSM3268133", "GSM3268134", "GSM3268135", "GSM3268136", "GSM3268137", "GSM3268138", "GSM3268139", "GSM3268140", "GSM3268141", "GSM3268142", "GSM3268143", "GSM3268144", "GSM3268145", "GSM3268146", "GSM3268147", "GSM3268148", "GSM3268149", "GSM3268150", "GSM3268151", "GSM3268152", "GSM3268153", "GSM3268154", "GSM3268155", "GSM3268156", "GSM3268157", "GSM3268158", "GSM3268159", "GSM3268160", "GSM3268161", "GSM3268162", "GSM3268163", "GSM3268164", "GSM3268165", "GSM3268166", "GSM3268167", "GSM3268168", "GSM3268169", "GSM3268170", "GSM3268171", "GSM3268172", "GSM3268173", "GSM3268174", "GSM3268175", "GSM3268176", "GSM3268177", "GSM3268178", "GSM3268179", "GSM3268180", "GSM3268181", "GSM3268182", "GSM3268183", "GSM3268184", "GSM3268185", "GSM3268186", "GSM3268187", "GSM3268188", "GSM3268189", "GSM3268190", "GSM3268191", "GSM3268192", "GSM3268193", "GSM3268194", "GSM3268195", "GSM3268196", "GSM3268197", "GSM3268198", "GSM3268199", "GSM3268200", "GSM3268201", "GSM3268202", "GSM3268203", "GSM3268204", "GSM3268205", "GSM3268206", "GSM3268207", "GSM3268208", "GSM3268209", "GSM3268210", "GSM3268211", "GSM3268212", "GSM3268213", "GSM3268214", "GSM3268215", "GSM3268216", "GSM3268217", "GSM3268218", "GSM3268219", "GSM3268220", "GSM3268221", "GSM3268222", "GSM3268223", "GSM3268224", "GSM3268225", "GSM3268226", "GSM3268227", "GSM3268228", "GSM3268229", "GSM3268230", "GSM3268231", "GSM3268232", "GSM3268233", "GSM3268234", "GSM3268235", "GSM3268236", "GSM3268237", "GSM3268238", "GSM3268239", "GSM3268240", "GSM3268241", "GSM3268242", "GSM3268243", "GSM3268244", "GSM3268245", "GSM3268246", "GSM3268247", "GSM3268248", "GSM3268249", "GSM3268250", "GSM3268251", "GSM3268252", "GSM3268253", "GSM3268254", "GSM3268255", "GSM3268256", "GSM3268257", "GSM3268258", "GSM3268259", "GSM3268260", "GSM3268261", "GSM3268262", "GSM3268263", "GSM3268264", "GSM3268265", "GSM3268266", "GSM3268267", "GSM3268268", "GSM3268269", "GSM3268270", "GSM3268271", "GSM3268272", "GSM3268273", "GSM3268274", "GSM3268275", "GSM3268276", "GSM3268277", "GSM3268278", "GSM3268279", "GSM3268280", "GSM3268281", "GSM3268282", "GSM3268283", "GSM3268284", "GSM3268285", "GSM3268286", "GSM3268287", "GSM3268288", "GSM3268289", "GSM3268290", "GSM3268291", "GSM3268292", "GSM3268293", "GSM3268294", "GSM3268295", "GSM3268296", "GSM3268297", "GSM3268298", "GSM3268299", "GSM3268300", "GSM3268301", "GSM3268302", "GSM3268303", "GSM3268304", "GSM3268305", "GSM3268306", "GSM3268307", "GSM3268308", "GSM3268309", "GSM3268310", "GSM3268311", "GSM3268312", "GSM3268313", "GSM3268314", "GSM3268315", "GSM3268316", "GSM3268317", "GSM3268318", "GSM3268319", "GSM3268320", "GSM3268321", "GSM3268322", "GSM3268323", "GSM3268324", "GSM3268325", "GSM3268326", "GSM3268327", "GSM3268328", "GSM3268329", "GSM3268330", "GSM3268331", "GSM3268332", "GSM3268333", "GSM3268334", "GSM3268335", "GSM3268336", "GSM3268337", "GSM3268338", "GSM3268339", "GSM3268340", "GSM3268341", "GSM3268342", "GSM3268343", "GSM3268344", "GSM3268345", "GSM3268346", "GSM3268347", "GSM3268348", "GSM3268349", "GSM3268350", "GSM3268351", "GSM3268352", "GSM3268353", "GSM3268354", "GSM3268355", "GSM3268356", "GSM3268357", "GSM3268358", "GSM3268359", "GSM3268360", "GSM3268361", "GSM3268362", "GSM3268363", "GSM3268364", "GSM3268365", "GSM3268366", "GSM3268367", "GSM3268368", "GSM3268369", "GSM3268370", "GSM3268371", "GSM3268372", "GSM3268373", "GSM3268374", "GSM3268375", "GSM3268376", "GSM3268377", "GSM3268378", "GSM3268379", "GSM3268380", "GSM3268381", "GSM3268382", "GSM3268383", "GSM3268384", "GSM3268385", "GSM3268386", "GSM3268387", "GSM3268388", "GSM3268389", "GSM3268390", "GSM3268391", "GSM3268392", "GSM3268393", "GSM3268394", "GSM3268395", "GSM3268396", "GSM3268397", "GSM3268398", "GSM3268399", "GSM3268400", "GSM3268401", "GSM3268402", "GSM3268403", "GSM3268404", "GSM3268405", "GSM3268406", "GSM3268407", "GSM3268408", "GSM3268409", "GSM3268410", "GSM3268411", "GSM3268412", "GSM3268413", "GSM3268414", "GSM3268415", "GSM3268416", "GSM3268417", "GSM3268418", "GSM3268419", "GSM3268420", "GSM3268421", "GSM3268422", "GSM3268423", "GSM3268424", "GSM3268425", "GSM3268426", "GSM3268427", "GSM3268428", "GSM3268429", "GSM3268430", "GSM3268431", "GSM3268432", "GSM3268433", "GSM3268434", "GSM3268435", "GSM3268436", "GSM3268437", "GSM3268438", "GSM3268439", "GSM3268440", "GSM3268441", "GSM3268442", "GSM3268443", "GSM3268444", "GSM3268445", "GSM3268446", "GSM3268447", "GSM3268448", "GSM3268449", "GSM3268450", "GSM3268451", "GSM3268452", "GSM3268453", "GSM3268454", "GSM3268455", "GSM3268456", "GSM3268457", "GSM3268458", "GSM3268459", "GSM3268460", "GSM3268461", "GSM3268462", "GSM3268463", "GSM3268464", "GSM3268465", "GSM3268466", "GSM3268467", "GSM3268468", "GSM3268469", "GSM3268470", "GSM3268471", "GSM3268472", "GSM3268473", "GSM3268474", "GSM3268475", "GSM3268476", "GSM3268477", "GSM3268478", "GSM3268479", "GSM3268480", "GSM3268481", "GSM3268482", "GSM3268483", "GSM3268484", "GSM3268485", "GSM3268486", "GSM3268487", "GSM3268488", "GSM3268489", "GSM3268490", "GSM3268491", "GSM3268492", "GSM3268493", "GSM3268494", "GSM3268495", "GSM3268496", "GSM3268497", "GSM3268498", "GSM3268499", "GSM3268500", "GSM3268501", "GSM3268502", "GSM3268503", "GSM3268504", "GSM3268505", "GSM3268506", "GSM3268507", "GSM3268508", "GSM3268509", "GSM3268510", "GSM3268511", "GSM3268512", "GSM3268513", "GSM3268514", "GSM3268515", "GSM3268516", "GSM3268517", "GSM3268518", "GSM3268519", "GSM3268520", "GSM3268521", "GSM3268522", "GSM3268523", "GSM3268524", "GSM3268525", "GSM3268526", "GSM3268527", "GSM3268528", "GSM3268529", "GSM3268530", "GSM3268531", "GSM3268532", "GSM3268533", "GSM3268534", "GSM3268535", "GSM3268536", "GSM3268537", "GSM3268538", "GSM3268539", "GSM3268540", "GSM3268541", "GSM3268542", "GSM3268543", "GSM3268544", "GSM3268545", "GSM3268546", "GSM3268547", "GSM3268548", "GSM3268549", "GSM3268550", "GSM3268551", "GSM3268552", "GSM3268553", "GSM3268554", "GSM3268555", "GSM3268556", "GSM3268557", "GSM3268558", "GSM3268559", "GSM3268560", "GSM3268561", "GSM3268562", "GSM3268563", "GSM3268564", "GSM3268565", "GSM3268566", "GSM3268567", "GSM3268568", "GSM3268569", "GSM3268570", "GSM3268571", "GSM3268572", "GSM3268573", "GSM3268574", "GSM3268575", "GSM3268576", "GSM3268577", "GSM3268578", "GSM3268579", "GSM3268580", "GSM3268581", "GSM3268582", "GSM3268583", "GSM3268584", "GSM3268585", "GSM3268586", "GSM3268587", "GSM3268588", "GSM3268589", "GSM3268590", "GSM3268591", "GSM3268592", "GSM3268593", "GSM3268594", "GSM3268595", "GSM3268596", "GSM3268597", "GSM3268598", "GSM3268599", "GSM3268600", "GSM3268601", "GSM3268602", "GSM3268603", "GSM3268604", "GSM3268605", "GSM3268606", "GSM3268607", "GSM3268608", "GSM3268609", "GSM3268610", "GSM3268611", "GSM3268612", "GSM3268613", "GSM3268614", "GSM3268615", "GSM3268616", "GSM3268617", "GSM3268618", "GSM3268619", "GSM3268620", "GSM3268621", "GSM3268622", "GSM3268623", "GSM3268624", "GSM3268625", "GSM3268626", "GSM3268627", "GSM3268628", "GSM3268629", "GSM3268630", "GSM3268631", "GSM3268632", "GSM3268633", "GSM3268634", "GSM3268635", "GSM3268636", "GSM3268637", "GSM3268638", "GSM3268639", "GSM3268640", "GSM3268641", "GSM3268642", "GSM3268643", "GSM3268644", "GSM3268645", "GSM3268646", "GSM3268647", "GSM3268648", "GSM3268649", "GSM3268650", "GSM3268651", "GSM3268652", "GSM3268653", "GSM3268654", "GSM3268655", "GSM3268656", "GSM3268657", "GSM3268658", "GSM3268659", "GSM3268660", "GSM3268661", "GSM3268662", "GSM3268663", "GSM3268664", "GSM3268665", "GSM3268666", "GSM3268667", "GSM3268668", "GSM3268669", "GSM3268670", "GSM3268671", "GSM3268672", "GSM3268673", "GSM3268674", "GSM3268675", "GSM3268676", "GSM3268677", "GSM3268678", "GSM3268679", "GSM3268680", "GSM3268681", "GSM3268682", "GSM3268683", "GSM3268684", "GSM3268685", "GSM3268686", "GSM3268687", "GSM3268688", "GSM3268689", "GSM3268690", "GSM3268691", "GSM3268692", "GSM3268693", "GSM3268694", "GSM3268695", "GSM3268696", "GSM3268697", "GSM3268698", "GSM3268699", "GSM3268700", "GSM3268701", "GSM3268702", "GSM3268703", "GSM3268704", "GSM3268705", "GSM3268706", "GSM3268707", "GSM3268708", "GSM3268709", "GSM3268710", "GSM3268711", "GSM3268712", "GSM3268713", "GSM3268714", "GSM3268715", "GSM3268716", "GSM3268717", "GSM3268718", "GSM3268719", "GSM3268720", "GSM3268721", "GSM3268722", "GSM3268723", "GSM3268724", "GSM3268725", "GSM3268726", "GSM3268727", "GSM3268728", "GSM3268729", "GSM3268730", "GSM3268731", "GSM3268732", "GSM3268733", "GSM3268734", "GSM3268735", "GSM3268736", "GSM3268737", "GSM3268738", "GSM3268739", "GSM3268740", "GSM3268741", "GSM3268742", "GSM3268743", "GSM3268744", "GSM3268745", "GSM3268746", "GSM3268747", "GSM3268748", "GSM3268749", "GSM3268750", "GSM3268751", "GSM3268752", "GSM3268753", "GSM3268754", "GSM3268755", "GSM3268756", "GSM3268757", "GSM3268758", "GSM3268759", "GSM3268760", "GSM3268761", "GSM3268762", "GSM3268763", "GSM3268764", "GSM3268765", "GSM3268766", "GSM3268767", "GSM3268768", "GSM3268769", "GSM3268770", "GSM3268771", "GSM3268772", "GSM3268773", "GSM3268774", "GSM3268775", "GSM3268776", "GSM3268777", "GSM3268778", "GSM3268779", "GSM3268780", "GSM3268781", "GSM3268782", "GSM3268783", "GSM3268784", "GSM3268785", "GSM3268786", "GSM3268787", "GSM3268788", "GSM3268789", "GSM3268790", "GSM3268791", "GSM3268792", "GSM3268793", "GSM3268794", "GSM3268795", "GSM3268796", "GSM3268797", "GSM3268798", "GSM3268799", "GSM3268800", "GSM3268801", "GSM3268802", "GSM3268803", "GSM3268804", "GSM3268805", "GSM3268806", "GSM3268807", "GSM3268808", "GSM3268809", "GSM3268810", "GSM3268811", "GSM3268812", "GSM3268813", "GSM3268814", "GSM3268815", "GSM3268816", "GSM3268817", "GSM3268818", "GSM3268819", "GSM3268820", "GSM3268821", "GSM3268822", "GSM3268823", "GSM3268824", "GSM3268825", "GSM3268826", "GSM3268827", "GSM3268828", "GSM3268829", "GSM3268830", "GSM3268831", "GSM3268832", "GSM3268833", "GSM3268834", "GSM3268835", "GSM3268836", "GSM3268837", "GSM3268838", "GSM3268839", "GSM3268840", "GSM3268841", "GSM3268842", "GSM3268843", "GSM3268844", "GSM3268845", "GSM3268846", "GSM3268847", "GSM3268848", "GSM3268849", "GSM3268850", "GSM3268851", "GSM3268852", "GSM3268853", "GSM3268854", "GSM3268855", "GSM3268856", "GSM3268857", "GSM3268858", "GSM3268859", "GSM3268860", "GSM3268861", "GSM3268862", "GSM3268863", "GSM3268864", "GSM3268865", "GSM3268866", "GSM3268867", "GSM3268868", "GSM3268869", "GSM3268870", "GSM3268871", "GSM3268872", "GSM3268873", "GSM3268874", "GSM3268875", "GSM3268876", "GSM3268877", "GSM3268878", "GSM3268879", "GSM3268880", "GSM3268881", "GSM3268882", "GSM3268883", "GSM3268884", "GSM3268885", "GSM3268886", "GSM3268887", "GSM3268888", "GSM3268889", "GSM3268890", "GSM3268891", "GSM3268892", "GSM3268893", "GSM3268894", "GSM3268895", "GSM3268896", "GSM3268897", "GSM3268898", "GSM3268899", "GSM3268900", "GSM3268901", "GSM3268902", "GSM3268903", "GSM3268904", "GSM3268905", "GSM3268906", "GSM3268907", "GSM3268908", "GSM3268909", "GSM3268910", "GSM3268911", "GSM3268912", "GSM3268913", "GSM3268914", "GSM3268915", "GSM3268916", "GSM3268917", "GSM3268918", "GSM3268919", "GSM3268920", "GSM3268921", "GSM3268922", "GSM3268923", "GSM3268924", "GSM3268925", "GSM3268926", "GSM3268927", "GSM3268928", "GSM3268929", "GSM3268930", "GSM3268931", "GSM3268932", "GSM3268933", "GSM3268934", "GSM3268935", "GSM3268936", "GSM3268937", "GSM3268938", "GSM3268939", "GSM3268940", "GSM3268941", "GSM3268942", "GSM3268943", "GSM3268944", "GSM3268945", "GSM3268946", "GSM3268947", "GSM3268948", "GSM3268949", "GSM3268950", "GSM3268951", "GSM3268952", "GSM3268953", "GSM3268954", "GSM3268955", "GSM3268956", "GSM3268957", "GSM3268958", "GSM3268959", "GSM3268960", "GSM3268961", "GSM3268962", "GSM3268963", "GSM3268964", "GSM3268965", "GSM3268966", "GSM3268967", "GSM3268968", "GSM3268969", "GSM3268970", "GSM3268971", "GSM3268972", "GSM3268973", "GSM3268974", "GSM3268975", "GSM3268976", "GSM3268977", "GSM3268978", "GSM3268979", "GSM3268980", "GSM3268981", "GSM3268982", "GSM3268983", "GSM3268984", "GSM3268985", "GSM3268986", "GSM3268987", "GSM3268988", "GSM3268989", "GSM3268990", "GSM3268991", "GSM3268992", "GSM3268993", "GSM3268994", "GSM3268995", "GSM3268996", "GSM3268997", "GSM3268998", "GSM3268999", "GSM3269000", "GSM3269001", "GSM3269002", "GSM3269003", "GSM3269004", "GSM3269005", "GSM3269006", "GSM3269007", "GSM3269008", "GSM3269009", "GSM3269010", "GSM3269011", "GSM3269012", "GSM3269013", "GSM3269014", "GSM3269015", "GSM3269016", "GSM3269017", "GSM3269018", "GSM3269019", "GSM3269020", "GSM3269021", "GSM3269022", "GSM3269023", "GSM3269024", "GSM3269025", "GSM3269026", "GSM3269027", "GSM3269028", "GSM3269029", "GSM3269030", "GSM3269031", "GSM3269032", "GSM3269033", "GSM3269034", "GSM3269035", "GSM3269036", "GSM3269037", "GSM3269038", "GSM3269039", "GSM3269040", "GSM3269041", "GSM3269042", "GSM3269043", "GSM3269044", "GSM3269045", "GSM3269046", "GSM3269047", "GSM3269048", "GSM3269049", "GSM3269050", "GSM3269051", "GSM3269052", "GSM3269053", "GSM3269054", "GSM3269055", "GSM3269056", "GSM3269057", "GSM3269058", "GSM3269059", "GSM3269060", "GSM3269061", "GSM3269062", "GSM3269063", "GSM3269064", "GSM3269065", "GSM3269066", "GSM3269067", "GSM3269068", "GSM3269069", "GSM3269070", "GSM3269071", "GSM3269072", "GSM3269073", "GSM3269074", "GSM3269075", "GSM3269076", "GSM3269077", "GSM3269078", "GSM3269079", "GSM3269080", "GSM3269081", "GSM3269082", "GSM3269083", "GSM3269084", "GSM3269085", "GSM3269086", "GSM3269087", "GSM3269088", "GSM3269089", "GSM3269090", "GSM3269091", "GSM3269092", "GSM3269093", "GSM3269094", "GSM3269095", "GSM3269096", "GSM3269097", "GSM3269098", "GSM3269099", "GSM3269100", "GSM3269101", "GSM3269102", "GSM3269103", "GSM3269104", "GSM3269105", "GSM3269106", "GSM3269107", "GSM3269108", "GSM3269109", "GSM3269110", "GSM3269111", "GSM3269112", "GSM3269113", "GSM3269114", "GSM3269115", "GSM3269116", "GSM3269117", "GSM3269118", "GSM3269119", "GSM3269120", "GSM3269121", "GSM3269122", "GSM3269123", "GSM3269124", "GSM3269125", "GSM3269126", "GSM3269127", "GSM3269128", "GSM3269129", "GSM3269130", "GSM3269131", "GSM3269132", "GSM3269133", "GSM3269134", "GSM3269135", "GSM3269136", "GSM3269137", "GSM3269138", "GSM3269139", "GSM3269140", "GSM3269141", "GSM3269142", "GSM3269143", "GSM3269144", "GSM3269145", "GSM3269146", "GSM3269147", "GSM3269148", "GSM3269149", "GSM3269150", "GSM3269151", "GSM3269152", "GSM3269153", "GSM3269154", "GSM3269155", "GSM3269156", "GSM3269157", "GSM3269158", "GSM3269159", "GSM3269160", "GSM3269161", "GSM3269162", "GSM3269163", "GSM3269164", "GSM3269165", "GSM3269166", "GSM3269167", "GSM3269168", "GSM3269169", "GSM3269170", "GSM3269171", "GSM3269172", "GSM3269173", "GSM3269174", "GSM3269175", "GSM3269176", "GSM3269177", "GSM3269178", "GSM3269179", "GSM3269180", "GSM3269181", "GSM3269182", "GSM3269183", "GSM3269184", "GSM3269185", "GSM3269186", "GSM3269187", "GSM3269188", "GSM3269189", "GSM3269190", "GSM3269191", "GSM3269192", "GSM3269193", "GSM3269194", "GSM3269195", "GSM3269196", "GSM3269197", "GSM3269198", "GSM3269199", "GSM3269200", "GSM3269201", "GSM3269202", "GSM3269203", "GSM3269204", "GSM3269205", "GSM3269206", "GSM3269207", "GSM3269208", "GSM3269209", "GSM3269210", "GSM3269211", "GSM3269212", "GSM3269213", "GSM3269214", "GSM3269215", "GSM3269216", "GSM3269217", "GSM3269218", "GSM3269219", "GSM3269220", "GSM3269221", "GSM3269222", "GSM3269223", "GSM3269224", "GSM3269225", "GSM3269226", "GSM3269227", "GSM3269228", "GSM3269229", "GSM3269230", "GSM3269231", "GSM3269232", "GSM3269233", "GSM3269234", "GSM3269235", "GSM3269236", "GSM3269237", "GSM3269238", "GSM3269239", "GSM3269240", "GSM3269241", "GSM3269242", "GSM3269243", "GSM3269244", "GSM3269245", "GSM3269246", "GSM3269247", "GSM3269248", "GSM3269249", "GSM3269250", "GSM3269251", "GSM3269252", "GSM3269253", "GSM3269254", "GSM3269255", "GSM3269256", "GSM3269257", "GSM3269258", "GSM3269259", "GSM3269260", "GSM3269261", "GSM3269262", "GSM3269263", "GSM3269264", "GSM3269265", "GSM3269266", "GSM3269267", "GSM3269268", "GSM3269269", "GSM3269270", "GSM3269271", "GSM3269272", "GSM3269273", "GSM3269274", "GSM3269275", "GSM3269276", "GSM3269277", "GSM3269278", "GSM3269279", "GSM3269280", "GSM3269281", "GSM3269282", "GSM3269283", "GSM3269284", "GSM3269285", "GSM3269286", "GSM3269287", "GSM3269288", "GSM3269289", "GSM3269290", "GSM3269291", "GSM3269292", "GSM3269293", "GSM3269294", "GSM3269295", "GSM3269296", "GSM3269297", "GSM3269298", "GSM3269299", "GSM3269300", "GSM3269301", "GSM3269302", "GSM3269303", "GSM3269304", "GSM3269305", "GSM3269306", "GSM3269307", "GSM3269308", "GSM3269309", "GSM3269310", "GSM3269311", "GSM3269312", "GSM3269313", "GSM3269314", "GSM3269315", "GSM3269316", "GSM3269317", "GSM3269318", "GSM3269319", "GSM3269320", "GSM3269321", "GSM3269322", "GSM3269323", "GSM3269324", "GSM3269325", "GSM3269326", "GSM3269327", "GSM3269328", "GSM3269329", "GSM3269330", "GSM3269331", "GSM3269332", "GSM3269333", "GSM3269334", "GSM3269335", "GSM3269336", "GSM3269337", "GSM3269338", "GSM3269339", "GSM3269340", "GSM3269341", "GSM3269342", "GSM3269343", "GSM3269344", "GSM3269345", "GSM3269346", "GSM3269347", "GSM3269348", "GSM3269349", "GSM3269350", "GSM3269351", "GSM3269352", "GSM3269353", "GSM3269354", "GSM3269355", "GSM3269356", "GSM3269357", "GSM3269358", "GSM3269359", "GSM3269360", "GSM3269361", "GSM3269362", "GSM3269363", "GSM3269364", "GSM3269365", "GSM3269366", "GSM3269367", "GSM3269368", "GSM3269369", "GSM3269370", "GSM3269371", "GSM3269372", "GSM3269373", "GSM3269374", "GSM3269375", "GSM3269376", "GSM3269377", "GSM3269378", "GSM3269379", "GSM3269380", "GSM3269381", "GSM3269382", "GSM3269383", "GSM3269384", "GSM3269385", "GSM3269386", "GSM3269387", "GSM3269388", "GSM3269389", "GSM3269390", "GSM3269391", "GSM3269392", "GSM3269393", "GSM3269394", "GSM3269395", "GSM3269396", "GSM3269397", "GSM3269398", "GSM3269399", "GSM3269400", "GSM3269401", "GSM3269402", "GSM3269403", "GSM3269404", "GSM3269405", "GSM3269406", "GSM3269407", "GSM3269408", "GSM3269409", "GSM3269410", "GSM3269411", "GSM3269412", "GSM3269413", "GSM3269414", "GSM3269415", "GSM3269416", "GSM3269417", "GSM3269418", "GSM3269419", "GSM3269420", "GSM3269421", "GSM3269422", "GSM3269423", "GSM3269424", "GSM3269425", "GSM3269426", "GSM3269427", "GSM3269428", "GSM3269429", "GSM3269430", "GSM3269431", "GSM3269432", "GSM3269433", "GSM3269434", "GSM3269435", "GSM3269436", "GSM3269437", "GSM3269438", "GSM3269439", "GSM3269440", "GSM3269441", "GSM3269442", "GSM3269443", "GSM3269444", "GSM3269445", "GSM3269446", "GSM3269447", "GSM3269448", "GSM3269449", "GSM3269450", "GSM3269451", "GSM3269452", "GSM3269453", "GSM3269454", "GSM3269455", "GSM3269456", "GSM3269457", "GSM3269458", "GSM3269459", "GSM3269460", "GSM3269461", "GSM3269462", "GSM3269463", "GSM3269464", "GSM3269465", "GSM3269466", "GSM3269467", "GSM3269468", "GSM3269469", "GSM3269470", "GSM3269471", "GSM3269472", "GSM3269473", "GSM3269474", "GSM3269475", "GSM3269476", "GSM3269477", "GSM3269478", "GSM3269479", "GSM3269480", "GSM3269481", "GSM3269482", "GSM3269483", "GSM3269484", "GSM3269485", "GSM3269486", "GSM3269487", "GSM3269488", "GSM3269489", "GSM3269490", "GSM3269491", "GSM3269492", "GSM3269493", "GSM3269494", "GSM3269495", "GSM3269496", "GSM3269497", "GSM3269498", "GSM3269499", "GSM3269500", "GSM3269501", "GSM3269502", "GSM3269503", "GSM3269504", "GSM3269505", "GSM3269506", "GSM3269507", "GSM3269508", "GSM3269509", "GSM3269510", "GSM3269511", "GSM3269512", "GSM3269513", "GSM3269514", "GSM3269515", "GSM3269516", "GSM3269517", "GSM3269518", "GSM3269519", "GSM3269520", "GSM3269521", "GSM3269522", "GSM3269523", "GSM3269524", "GSM3269525", "GSM3269526", "GSM3269527", "GSM3269528", "GSM3269529", "GSM3269530", "GSM3269531", "GSM3269532", "GSM3269533", "GSM3269534", "GSM3269535", "GSM3269536", "GSM3269537", "GSM3269538", "GSM3269539", "GSM3269540", "GSM3269541", "GSM3269542", "GSM3269543", "GSM3269544", "GSM3269545", "GSM3269546", "GSM3269547", "GSM3269548", "GSM3269549", "GSM3269550", "GSM3269551", "GSM3269552", "GSM3269553", "GSM3269554", "GSM3269555", "GSM3269556", "GSM3269557", "GSM3269558", "GSM3269559", "GSM3269560", "GSM3269561", "GSM3269562", "GSM3269563", "GSM3269564", "GSM3269565", "GSM3269566", "GSM3269567", "GSM3269568", "GSM3269569", "GSM3269570", "GSM3269571", "GSM3269572", "GSM3269573", "GSM3269574", "GSM3269575", "GSM3269576", "GSM3269577", "GSM3269578", "GSM3269579", "GSM3269580", "GSM3269581", "GSM3269582", "GSM3269583", "GSM3269584", "GSM3269585", "GSM3269586", "GSM3269587", "GSM3269588", "GSM3269589", "GSM3269590", "GSM3269591", "GSM3269592", "GSM3269593", "GSM3269594", "GSM3269595", "GSM3269596", "GSM3269597", "GSM3269598", "GSM3269599", "GSM3269600", "GSM3269601", "GSM3269602", "GSM3269603", "GSM3269604", "GSM3269605", "GSM3269606", "GSM3269607", "GSM3269608", "GSM3269609", "GSM3269610", "GSM3269611", "GSM3269612", "GSM3269613", "GSM3269614", "GSM3269615", "GSM3269616", "GSM3269617", "GSM3269618", "GSM3269619", "GSM3269620", "GSM3269621", "GSM3269622", "GSM3269623", "GSM3269624", "GSM3269625", "GSM3269626", "GSM3269627", "GSM3269628", "GSM3269629", "GSM3269630", "GSM3269631", "GSM3269632", "GSM3269633", "GSM3269634", "GSM3269635", "GSM3269636", "GSM3269637", "GSM3269638", "GSM3269639", "GSM3269640", "GSM3269641", "GSM3269642", "GSM3269643", "GSM3269644", "GSM3269645", "GSM3269646", "GSM3269647", "GSM3269648", "GSM3269649", "GSM3269650", "GSM3269651", "GSM3269652", "GSM3269653", "GSM3269654", "GSM3269655", "GSM3269656", "GSM3269657", "GSM3269658", "GSM3269659", "GSM3269660", "GSM3269661", "GSM3269662", "GSM3269663", "GSM3269664", "GSM3269665", "GSM3269666", "GSM3269667", "GSM3269668", "GSM3269669", "GSM3269670", "GSM3269671", "GSM3269672", "GSM3269673", "GSM3269674", "GSM3269675", "GSM3269676", "GSM3269677", "GSM3269678", "GSM3269679", "GSM3269680", "GSM3269681", "GSM3269682", "GSM3269683", "GSM3269684", "GSM3269685", "GSM3269686", "GSM3269687", "GSM3269688", "GSM3269689", "GSM3269690", "GSM3269691", "GSM3269692", "GSM3269693", "GSM3269694", "GSM3269695", "GSM3269696", "GSM3269697", "GSM3269698", "GSM3269699", "GSM3269700", "GSM3269701", "GSM3269702", "GSM3269703", "GSM3269704", "GSM3269705", "GSM3269706", "GSM3269707", "GSM3269708", "GSM3269709", "GSM3269710", "GSM3269711", "GSM3269712", "GSM3269713", "GSM3269714", "GSM3269715", "GSM3269716", "GSM3269717", "GSM3269718", "GSM3269719", "GSM3269720", "GSM3269721", "GSM3269722", "GSM3269723", "GSM3269724", "GSM3269725", "GSM3269726", "GSM3269727", "GSM3269728", "GSM3269729", "GSM3269730", "GSM3269731", "GSM3269732", "GSM3269733", "GSM3269734", "GSM3269735", "GSM3269736", "GSM3269737", "GSM3269738", "GSM3269739", "GSM3269740", "GSM3269741", "GSM3269742", "GSM3269743", "GSM3269744", "GSM3269745", "GSM3269746", "GSM3269747", "GSM3269748", "GSM3269749", "GSM3269750", "GSM3269751", "GSM3269752", "GSM3269753", "GSM3269754", "GSM3269755", "GSM3269756", "GSM3269757", "GSM3269758", "GSM3269759", "GSM3269760", "GSM3269761", "GSM3269762", "GSM3269763", "GSM3269764", "GSM3269765", "GSM3269766", "GSM3269767", "GSM3269768", "GSM3269769", "GSM3269770", "GSM3269771", "GSM3269772", "GSM3269773", "GSM3269774", "GSM3269775", "GSM3269776", "GSM3269777", "GSM3269778", "GSM3269779", "GSM3269780", "GSM3269781", "GSM3269782", "GSM3269783", "GSM3269784", "GSM3269785", "GSM3269786", "GSM3269787", "GSM3269788", "GSM3269789", "GSM3269790", "GSM3269791", "GSM3269792", "GSM3269793", "GSM3269794", "GSM3269795", "GSM3269796", "GSM3269797", "GSM3269798", "GSM3269799", "GSM3269800", "GSM3269801", "GSM3269802", "GSM3269803", "GSM3269804", "GSM3269805", "GSM3269806", "GSM3269807", "GSM3269808", "GSM3269809", "GSM3269810", "GSM3269811", "GSM3269812", "GSM3269813", "GSM3269814", "GSM3269815", "GSM3269816", "GSM3269817", "GSM3269818", "GSM3269819", "GSM3269820", "GSM3269821", "GSM3269822", "GSM3269823", "GSM3269824", "GSM3269825", "GSM3269826", "GSM3269827", "GSM3269828", "GSM3269829", "GSM3269830", "GSM3269831", "GSM3269832", "GSM3269833", "GSM3269834", "GSM3269835", "GSM3269836", "GSM3269837", "GSM3269838", "GSM3269839", "GSM3269840", "GSM3269841", "GSM3269842", "GSM3269843", "GSM3269844", "GSM3269845", "GSM3269846", "GSM3269847", "GSM3269848", "GSM3269849", "GSM3269850", "GSM3269851", "GSM3269852", "GSM3269853", "GSM3269854", "GSM3269855", "GSM3269856", "GSM3269857", "GSM3269858", "GSM3269859", "GSM3269860", "GSM3269861", "GSM3269862", "GSM3269863", "GSM3269864", "GSM3269865", "GSM3269866", "GSM3269867"], "sample_count": 1785, "group_sizes": null, "group_sizes_basis": null, "platform": "21263", "taxon": "Homo sapiens", "title": "Serum miRNA-based risk prediction for stroke", "resolution_checked_at": "2026-11-01T15:39:54Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE58294", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE58294", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE58294", "version": null, "note": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM1406033", "GSM1406034", "GSM1406035", "GSM1406036", "GSM1406037", "GSM1406038", "GSM1406039", "GSM1406040", "GSM1406041", "GSM1406042", "GSM1406043", "GSM1406044", "GSM1406045", "GSM1406046", "GSM1406047", "GSM1406048", "GSM1406049", "GSM1406050", "GSM1406051", "GSM1406052", "GSM1406053", "GSM1406054", "GSM1406055", "GSM1406056", "GSM1406057", "GSM1406058", "GSM1406059", "GSM1406060", "GSM1406061", "GSM1406062", "GSM1406063", "GSM1406064", "GSM1406065", "GSM1406066", "GSM1406067", "GSM1406068", "GSM1406069", "GSM1406070", "GSM1406071", "GSM1406072", "GSM1406073", "GSM1406074", "GSM1406075", "GSM1406076", "GSM1406077", "GSM1406078", "GSM1406079", "GSM1406080", "GSM1406081", "GSM1406082", "GSM1406083", "GSM1406084", "GSM1406085", "GSM1406086", "GSM1406087", "GSM1406088", "GSM1406089", "GSM1406090", "GSM1406091", "GSM1406092", "GSM1406093", "GSM1406094", "GSM1406095", "GSM1406096", "GSM1406097", "GSM1406098", "GSM1406099", "GSM1406100", "GSM1406101", "GSM1406102", "GSM1406103", "GSM1406104", "GSM1406105", "GSM1406106", "GSM1406107", "GSM1406108", "GSM1406109", "GSM1406110", "GSM1406111", "GSM1406112", "GSM1406113", "GSM1406114", "GSM1406115", "GSM1406116", "GSM1406117", "GSM1406118", "GSM1406119", "GSM1406120", "GSM1406121", "GSM1406122", "GSM1406123", "GSM1406124"], "sample_count": 92, "group_sizes": null, "group_sizes_basis": null, "platform": "570", "taxon": "Homo sapiens", "title": "Gene Expression Following Cardioembolic Stroke", "resolution_checked_at": "2026-11-01T15:39:54Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}, {"id": "data:geo:GSE95204", "role": "raw", "format": "geo-series", "media_type": "application/vnd.ncbi.geo-series+json", "uri": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE95204", "sha256": null, "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "GSE95204", "version": null, "note": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "structure": {"repository": "GEO", "access_route": "GEO accession URL", "access_statement_verbatim": "Data supporting the results of the study can be available by emailing the first author or corresponding author.", "access_statement_kind": "data_availability_statement", "sample_accessions": ["GSM2498620", "GSM2498621", "GSM2498622", "GSM2498623", "GSM2498624", "GSM2498625", "GSM2498626", "GSM2498627", "GSM2498628"], "sample_count": 9, "group_sizes": null, "group_sizes_basis": null, "platform": "18058", "taxon": "Homo sapiens; Mus musculus; Rattus norvegicus", "title": "Plasma miRNAs expression in acute ischemic stroke patients with or without recombinant tissue plasminogen activator treatment.", "resolution_checked_at": "2026-11-01T17:30:42Z", "resolution_check": "identifier_resolution_only_no_download_no_licence_read", "downloaded": false, "licence_read": false}}], "gaps": ["asset:data:geo:GSE117064 not downloaded", "asset:data:geo:GSE117064 licence not read", "asset:data:geo:GSE58294 not downloaded", "asset:data:geo:GSE58294 licence not read", "asset:data:geo:GSE95204 not downloaded", "asset:data:geo:GSE95204 licence not read"]}, "analysis": {"state": "partial", "methods": [{"id": "method-1", "family": "group_comparison", "specific": "student_t_test", "label": "Group comparison", "dsl_operations": [], "missing_operations": ["student_t"], "expressible": false, "parameters": {}, "data_shapes": ["two_or_more_groups_continuous"], "evidence": {"score": 1.0, "band": "verbatim", "quote": "Student's t-test and one-way ANOVA were used to compare the means of two or more groups. The Cox proportional-hazards model was used for multivariate analyses."}}, {"id": "method-2", "family": "group_comparison", "specific": "anova", "label": "Group comparison", "dsl_operations": ["group_summary", "welch_t", "bootstrap_mean_difference", "group_comparison_anova"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["two_or_more_groups_continuous"], "evidence": {"score": 0.8, "band": "high", "quote": "ANOVA"}}, {"id": "method-3", "family": "network_analysis", "specific": "ppi_network", "label": "Network / pathway analysis", "dsl_operations": ["build_graph", "centrality_scores", "pathway_enrich"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["edge_list"], "evidence": {"score": 0.7, "band": "medium", "quote": "PPI"}}, {"id": "method-4", "family": "network_analysis", "specific": "pathway_enrichment", "label": "Network / pathway analysis", "dsl_operations": ["pathway_enrich"], "missing_operations": [], "expressible": true, "parameters": {}, "data_shapes": ["edge_list"], "evidence": {"score": 0.7, "band": "medium", "quote": "pathway enrichment"}}], "targets": [], "gaps": ["method.student_t"]}, "capability": {"state": "complete", "requirements": [{"capability_id": "capability:computational_analysis", "label": "Computational analysis platform", "assay_families": ["meta_analysis", "machine_learning", "survival_analysis", "statistical_regression", "pca", "molecular_docking", "network_analysis", "differential_expression", "gwas"], "availability_state": "owned", "tier_unlocked": "R1", "candidate": "Automated Assays Laravel application and simulated adapters"}], "gaps": []}, "readiness": {"state": "complete", "tier": "R1", "blocking_axis": "none", "blocked_on": "nothing:replicable_now", "axes": {"method": {"tier": "R1", "expressible": false, "required_operations": [], "missing_operations": ["student_t"], "basis": "The paper names the method it used and the corpus's method extractor maps it onto the DSL catalogue: student_t_test."}, "capability": {"tier": "R1", "capability_id": "capability:computational_analysis", "availability_state": "owned", "basis": "The computational analysis is owned. The physical bench the paper used is not, so a physical validation cannot be run here."}, "data": {"tier": "R1", "reachable": true, "accessions": ["GSE95204", "GSE117064", "GSE58294"], "resolved_accessions": ["GSE95204", "GSE117064", "GSE58294"], "statements": ["Data supporting the results of the study can be available by emailing the first author or corresponding author."], "basis": "The paper names GSE95204, GSE117064, GSE58294 in Gene Expression Omnibus (GEO) and the accession resolves in the repository. No dataset was downloaded and no licence was read."}}, "can_run": {"dsl_operations": [], "assets": ["source:pmid:34938355", "data:geo:GSE117064"], "steps": []}, "must_build": {"dsl_operations": [{"operation": "student_t", "unlocks_papers": null, "priority": null}], "converters": [], "readers": [], "capabilities": [], "data_gaps": ["data:geo:GSE117064"]}, "gaps": []}, "review": {"state": "partial", "machine_critique": {"kind": "extraction_review", "reader": {"model": "MiniMax-M3.1-Flash", "provider": "minimax", "provider_family": "minimax", "read_at": "2026-11-01T17:12:28Z", "independence": "single_reader"}, "evidence_check": {"method": "verbatim", "availability": "verbatim"}, "calls": 5, "usage": {"prompt_tokens": 7033, "completion_tokens": 1377, "cached_tokens": 188}}, "human_critique": null, "stages": [{"id": "extraction", "state": "complete", "reader": "MiniMax-M3.1-Flash", "provider": "minimax"}], "gaps": ["review.independent_reader", "review.machine_critique", "review.human_critique"]}, "execution": {"state": "absent", "status": "not_run", "mode": null, "runs": [], "gaps": ["execution.not_run"]}, "provenance": {"entities": [{"id": "pmid:34938355", "type": "paper", "label": "pmid:34938355"}, {"id": "source:pmid:34938355", "type": "manuscript", "label": "PMID 34938355 full text"}, {"id": "data:geo:GSE117064", "type": "dataset", "label": "GEO GSE117064"}], "activities": [{"id": "activity-reading-sci-2026-11-01", "type": "classification", "used": [{"id": "pmid:34938355", "type": "paper", "label": "pmid:34938355"}, {"id": "source:pmid:34938355", "type": "manuscript", "label": "PMID 34938355 full text"}, {"id": "data:geo:GSE117064", "type": "dataset", "label": "GEO GSE117064"}], "agent": "agent:corpus-assay-engine"}, {"id": "activity-read-34938355", "type": "extraction", "used": ["source:pmid:34938355"], "agent": "agent:minimax-reader"}, {"id": "activity-resolve-GSE117064", "type": "accession_resolution", "used": ["data:geo:GSE117064"], "agent": "agent:corpus-assay-engine"}], "agents": [{"id": "agent:corpus-assay-engine", "type": "software", "label": "Corpus assay engine"}, {"id": "agent:minimax-reader", "type": "software", "label": "MiniMax literature reader"}], "source_run_id": "reading-sci-2026-11-01", "dsl_catalogue_fingerprint": "343fb30756ba6ec3", "capability_table_fingerprint": "2cb3e42f047d2ecf", "snapshot_id": "ba34b49490d9bfaf"}, "lineage": {"parent_id": "pmid:34938355", "parent_hash": "sha256:ec721d51eb6fd5046727e643d3e335f538df64592486b8765ea71998cfab0250", "fork_of": null, "generation": 4}, "gaps": ["asset:data:geo:GSE117064 licence not read", "asset:data:geo:GSE117064 not downloaded", "asset:data:geo:GSE58294 licence not read", "asset:data:geo:GSE58294 not downloaded", "asset:data:geo:GSE95204 licence not read", "asset:data:geo:GSE95204 not downloaded", "execution.not_run", "method.student_t", "review.human_critique", "review.independent_reader", "review.machine_critique", "step:run_analysis blocked on method:student_t"], "assays": [{"role": "data_generation", "definition_id": "microarray", "definition_version": "99e1195c7d6f", "definition_digest": null, "required_operations": [], "support_state": "partial", "source_hashes": {"assay_lexicon": "99e1195c7d6f"}, "confidence": 0.77, "evidence": ["dataset was composed on the GPL570 platform (Affymetrix Human Genome U133 Plus 2.0 Array). Samples o"], "order_basis": "paper_text_order:2067", "id": "assay:1"}, {"role": "analysis", "definition_id": "group_comparison", "definition_version": "f2132e96ae6c7a4e", "definition_digest": null, "required_operations": [], "support_state": "partial", "source_hashes": {"dsl_catalogue": "f2132e96ae6c7a4e"}, "confidence": 1.0, "evidence": ["Student's t-test and one-way ANOVA were used to compare the means of two or more groups. The Cox proportional-hazards model was used for multivariate analyses."], "order_basis": "consumes_earlier_output", "id": "assay:2"}]}