Transcriptome analysis of childhood Guillain-Barré syndrome associated with supportive care.

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We identified two distinct down-regulated genes (PTGDS and AR) in GBS by transcriptome analysis (n = 20). Based on the two distinct down-regulated genes in the GBS group, a two-gene diagnostic signature was developed. Moreover, gene expression analysis for the two-gene was performed on a patient with GBS before and after Supportive Care. RT-PCR results show that the expression of PTGDS increased after the patient was given supportive care. 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