Data from a proteomic comparative analysis highlight differential adaptation of Lactobacillus delbrueckii subsp. bulgaricus to cow milk versus to soy milk environments.

{"sci_version": "1.2", "schema": "https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json", "id": "pmid:36426081", "kind": "science-record", "revision": 4, "content_hash": "sha256:048c26d8117c6bccb5e55ce2303514ca1e65b5cfe4823d1636fafbc75e61e25e", "created_at": "2026-11-01T19:00:54Z", "updated_at": "2026-11-01T22:50:40Z", "generator": {"name": "corpus-assay-engine", "run_id": "reading-sci-2026-11-01"}, "paper": {"state": "complete", "title": "Data from a proteomic comparative analysis highlight differential adaptation of Lactobacillus delbrueckii subsp. bulgaricus to cow milk versus to soy milk environments.", "doi": "10.1016/j.dib.2022.108653", "pmid": "36426081", "authors": ["Gwénaël Jan", "Florian Tarnaud", "Fillipe Luiz Rosa do Carmo", "Nassima Illikoud", "Fanny Canon", "Julien Jardin", "Valérie Briard-Bion", "Fanny Guyomarc'h", "Valérie Gagnaire"], "journal": "Data in brief", "year": 2022, "abstract": "The article presents a proteomic dataset generated by a comparative analysis, using gel-free nanoLC-MS/MS, of the cellular proteome of Lactobacillus delbrueckii subsp. bulgaricus, a yogurt starter, when cultivated in soy milk versus in cow milk. The CIRM-BIA1592 strain was cultivated in the aqueous phase of soy milk, or of cow milk. Whole-cell proteins were extracted, trypsinolyzed and analyzed by nano LC-MS/MS, prior to identification and to classification by function using the X!Tandem pipeline software and the proteomic data from NCBI.nlm.nigh.gov. Quantification of the proteins was moreover performed to evidence changes in their expression, depending on the culture medium. Data are available via ProteomeXchange with the identifier PXD033905 (http://www.proteomexchange.org/). This article is related to the research article entitled \"The stressing life of Lactobacillus delbrueckii subsp. bulgaricus in soy milk\", by G.Jan et al. in Food Microbiology, 2022. This proteomic differential analysis indeed revealed major modulation of the stress proteome, with many stress proteins upregulated in the soy environment.", "claims": [{"id": "claim-method", "statement": "Proteins with a significant (p < 0.05, ANOVA) change in expression of ≥ 2-fold (log2 ratio ≥ 1.5) were considered differentially expressed.", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:36426081", "locator": "sections[7] \"Label-Free Proteomics\" paragraph 6", "quote": "Proteins with a significant (p < 0.05, ANOVA) change in expression of ≥ 2-fold (log2 ratio ≥ 1.5) were considered differentially expressed."}], "state": "complete"}, {"id": "claim-data-access", "statement": "Data from a proteomic comparative analysis highlight differential adaptation of Lactobacillus delbrueckii subsp. bulgaricus to cow milk versus to soy milk environments (Original data) (PRIDE).", "kind": "methodological", "target": null, "evidence": [{"asset": "source:pmid:36426081", "locator": "sections[11] \"Data Availability\" paragraph 2", "quote": "Data from a proteomic comparative analysis highlight differential adaptation of Lactobacillus delbrueckii subsp. bulgaricus to cow milk versus to soy milk environments (Original data) (PRIDE)."}], "state": "complete"}, {"id": "claim-target-result", "statement": "This proteomic differential analysis indeed revealed major modulation of the stress proteome, with many stress proteins upregulated in the soy environment.", "kind": "qualitative", "target": null, "evidence": [{"asset": "source:pmid:36426081", "locator": "sections[0] \"Abstract\" paragraph 1", "quote": "This proteomic differential analysis indeed revealed major modulation of the stress proteome, with many stress proteins upregulated in the soy environment."}], "state": "complete"}], "gaps": []}, "experiment": {"state": "complete", "objective": "This proteomic differential analysis indeed revealed major modulation of the stress proteome, with many stress proteins upregulated in the soy environment.", "steps": [{"id": "read_published_estimate", "order": 1, "name": "Read the published estimate from the source", "kind": "other", "state": "complete", "blocked_on": null, "description": "The claim, method and evidence span published with the source article.", "duration_hours": null, "parameters": {}, "inputs": ["source:pmid:36426081"], "outputs": ["the published estimate and its evidence"], "instruments": [], "reagents": []}, {"id": "obtain_source_data", "order": 2, "name": "Obtain the source data from the named repository", "kind": "data-preparation", "state": "complete", "blocked_on": null, "description": "The GEO series accession resolves and its sample accessions are listed. 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