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pmid:39773464

Prognostic significance of CDK1 expression in diffuse large B-Cell lymphoma.

BMC cancer · 2025 doi:10.1186/s12885-024-13388-y

Paper

partial

Experiment

partial

Data

partial

Analysis

absent

Execution

absent

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Record details sci_version · id · kind · revision · content_hash · schema · created_at · updated_at · generator
id
pmid:39773464
kind
science-record
content_hash
sha256:598f4ae1605715aa220267beaf7883e1971b707d3a4e8942c3d59f2b110cc66f
schema
https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json
created_at
2026-11-01T10:25:48Z
updated_at
2026-11-01T14:01:32Z
generator object · 3 fields
name
corpus-assay-engine
converter
sep_to_sci_v1
source_package_schema
urn:bntrg:sep:1.0.0
paper object · 10 fields
state
partial
title
Prognostic significance of CDK1 expression in diffuse large B-Cell lymphoma.
doi
10.1186/s12885-024-13388-y
pmid
39773464
authors
null
journal
BMC cancer
year
2025
abstract
null
claims array · 1 item
[0] object · 6 fields
id
claim-1
statement
the headline numerical result the paper states for its main finding
kind
qualitative
state
blocked
target object · 4 fields
value
null
unit
null
tolerance
null
source
null
evidence array · 0 items
gaps array · 2 items
[0]
abstract
[1]
authors
experiment object · 8 fields
state
partial
objective
the headline numerical result the paper states for its main finding
steps array · 3 items
[0] object · 13 fields
id
read_published_estimate
order
1
name
Read the published estimate and its interval from the source
kind
other
state
complete
blocked_on
null
description
The number a replication must land on, and the sentence it came from.
parameters object · 0 fields
inputs array · 1 item
[0]
source:pmid:39773464
outputs array · 1 item
[0]
the published estimate, its unit and its interval
instruments array · 0 items
reagents array · 0 items
[1] object · 13 fields
id
obtain_source_data
order
2
name
Obtain the source data behind the published result
kind
data-preparation
state
blocked
blocked_on
data:not_downloaded
description
The published result cannot be recomputed without the data the paper analysed.
parameters object · 0 fields
inputs array · 0 items
outputs array · 1 item
[0]
the source data with its provenance
instruments array · 0 items
reagents array · 0 items
[2] object · 13 fields
id
run_analysis
order
3
name
Run the analysis programme
kind
analysis
state
blocked
blocked_on
no owned computational capability is bound to this experiment
description
Re-run the paper's analysis on the source data and produce the registered result. | SEP input not carried into the asset list: materials:the source data behind the published result in pmid:39773464
parameters object · 0 fields
inputs array · 0 items
outputs array · 1 item
[0]
the registered result
instruments array · 0 items
reagents array · 0 items
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conditions object · 0 fields
gaps array · 3 items
[0]
step:obtain_source_data blocked on data:not_downloaded
[1]
step:run_analysis blocked on no owned computational capability is bound to this experiment
[2]
step:run_analysis input 'materials:the source data behind the published result in pmid:39773464' does not resolve to a declared asset
data object · 3 fields
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partial
assets array · 2 items
[0] object · 15 fields
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source:pmid:39773464
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manuscript
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xml
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application/xml
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https://doi.org/10.1186/s12885-024-13388-y
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reader_required
identifier
10.1186/s12885-024-13388-y
version
null
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Source read by the package builder: full_text.
structure object · 1 field
access_state
full_text
[1] object · 16 fields
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asset:table:pmid:39773464:1
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jats-table
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section[12]/table-wrap[1]#Tab1
version
null
note
Characteristics of 306 subjects with diffuse large B-cell lymphoma (DLBCL)
structure object · 5 fields
pmcid
PMC11705832
section_index
12
section_title
CDK1 expression and characteristics of DLBCL patients
row_count
31
column_count
5
table object · 8 fields
label
Table 1
caption
Characteristics of 306 subjects with diffuse large B-cell lymphoma (DLBCL)
rows array · 31 items
[0] array · 5 items
[0]
Characteristics
[1]
Total(n = 306)
[2]
CDK1-high(n = 45)
[3]
CDK1-low (n = 261)
[4]
P
[1] array · 5 items
[0]
Gender(%)
[1]
[2]
[3]
[4]
0.674
[2] array · 5 items
[0]
male
[1]
172(56.21)
[2]
24(53.33)
[3]
148(56.70)
[4]
[3] array · 5 items
[0]
female
[1]
134(43.79)
[2]
21(46.67)
[3]
113(43.30)
[4]
[4] array · 5 items
[0]
Age(%)
[1]
[2]
[3]
[4]
0.429
[5] array · 5 items
[0]
<60
[1]
139(45.42)
[2]
18(40)
[3]
121(46.36)
[4]
[6] array · 5 items
[0]
≥ 60
[1]
167(54.58)
[2]
27(60)
[3]
140(53.64)
[4]
[7] array · 5 items
[0]
Cell of origin(%)
[1]
[2]
[3]
[4]
0.104
[8] array · 5 items
[0]
GCB
[1]
134(43.79)
[2]
26(57.78)
[3]
108(41.38)
[4]
[9] array · 5 items
[0]
ABC
[1]
125(40.85)
[2]
15(33.33)
[3]
110(42.15)
[4]
[10] array · 5 items
[0]
UC
[1]
47(15.36)
[2]
4(8.89)
[3]
43(16.48)
[4]
[11] array · 5 items
[0]
Count of extranodalinvasion(%)
[1]
[2]
[3]
[4]
0.100
[12] array · 5 items
[0]
0
[1]
190(62.09)
[2]
23(51.11)
[3]
167(63.98)
[4]
[13] array · 5 items
[0]
≥ 1
[1]
116(30.39)
[2]
22(48.89)
[3]
94(36.02)
[4]
[14] array · 5 items
[0]
LDH ratio(%)
[1]
[2]
[3]
[4]
0.022
[15] array · 5 items
[0]
≤ 1
[1]
157(51.31)
[2]
16(35.56)
[3]
141(54.02)
[4]
[16] array · 5 items
[0]
>1
[1]
149(48.69)
[2]
29(64.44)
[3]
120(45.98)
[4]
[17] array · 5 items
[0]
Ann-Arbor stage(%)
[1]
[2]
[3]
[4]
0.307
[18] array · 5 items
[0]
I
[1]
50(16.34)
[2]
7(15.57)
[3]
43(16.48)
[4]
[19] array · 5 items
[0]
II
[1]
94(30.71)
[2]
14(31.11)
[3]
80(30.65)
[4]
[20] array · 5 items
[0]
III
[1]
69(22.55)
[2]
6(13.33)
[3]
63(24.14)
[4]
[21] array · 5 items
[0]
IV
[1]
93(30.39)
[2]
18(40)
[3]
75(28.74)
[4]
[22] array · 5 items
[0]
ECOG(%)
[1]
[2]
[3]
[4]
0.386
[23] array · 5 items
[0]
0
[1]
69(22.55)
[2]
7(15.56)
[3]
62(23.75)
[4]
[24] array · 5 items
[0]
1
[1]
162(52.94)
[2]
24(53.33)
[3]
138(52.87)
[4]
[25] array · 5 items
[0]
2
[1]
48(15.69)
[2]
7(15.56)
[3]
41(15.71)
[4]
[26] array · 5 items
[0]
3
[1]
22(7.19)
[2]
5(11.11)
[3]
17(6.51)
[4]
[27] array · 5 items
[0]
4
[1]
5(1.63)
[2]
2(4.44)
[3]
3(1.15)
[4]
[28] array · 5 items
[0]
Treatment(%)
[1]
[2]
[3]
[4]
0.183
[29] array · 5 items
[0]
CHOP-like
[1]
142(46.41)
[2]
25(55.56)
[3]
117(44.83)
[4]
[30] array · 5 items
[0]
R-CHOP-like
[1]
164(53.59)
[2]
20(44.44)
[3]
144(55.17)
[4]
locator
section[12]/table-wrap[1]#Tab1
gaps array · 1 item
[0]
asset:source:pmid:39773464 not verified
analysis object · 4 fields
state
absent
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gaps array · 2 items
[0]
method
[1]
targets
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absent
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gaps array · 1 item
[0]
capability
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partial
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null
blocked_on
null
axes object · 0 fields
can_run object · 3 fields
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[0]
source:pmid:39773464
[1]
asset:table:pmid:39773464:1
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[0]
read_published_estimate
must_build object · 5 fields
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[0]
xml
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data_gaps array · 1 item
[0]
source:pmid:39773464
gaps array · 1 item
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corpus_record_absent
review object · 5 fields
state
partial
machine_critique object · 7 fields
status
passed
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[0] object · 7 fields
provider
minimax
model
MiniMax-M3.1-Flash
prompt_version
full-text-reading-v1
prompt_hash
ba2b28d06d0423fae4bcba15c6fe1e70c0024d80eaffa1b19b2f862d51f32a37
source_hash
e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212
raw_response_sha256
sha256:75ae0945f8b1a3f536253c70e2d7dfb39eacbfd7961c715da6776220309357d4
raw_response_chars
4612
[1] object · 7 fields
provider
minimax_alt
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MiniMax-M3
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full-text-reading-v1
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b7068d9947246be683657417e8caafbce57d24364d7b46bfbea2f9518b25038d
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e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212
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sha256:9091ae7a3b384543e0bfc2496ec07b35a15bd689804ea5490241da964476d52f
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49197
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[0] object · 8 fields
provider
minimax
model
MiniMax-M3.1-Flash
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replication-target-v2
prompt_hash
f22c21d028ec1f95ab3c2e61dcddabc382a204af0d9d9646843714767564f533
source_hash
e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212
raw_response
{"parent_value":0,"unit":"","evidence":"","target_result":"The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with diffuse large B-cell lymphoma, but it does not state a numerical result for this main finding.","number_stated":false}
reading object · 6 fields
parent_value
0
unit
evidence
target_result
The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with diffuse large B-cell lymphoma, but it does not state a numerical result for this main finding.
number_stated
false
source_locator
null
recorded_at
2026-10-31T15:19:00.404573+00:00
[1] object · 8 fields
provider
minimax_alt
model
MiniMax-M3
prompt_version
replication-target-v2
prompt_hash
48bcb7c9b888839624d74d0a24a0b6147386f6958c7915e8e08a452b6e9c8dbb
source_hash
e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212
raw_response
<think>We need answer JSON only. Need interpret task carefully. Need find single numerical result replication registered target headline numerical result paper states for main finding. Source text provided seems abstract/methods without actual specific main finding numeric values. It has methodological numbers (1×106 cells/well, 10 µM, 24h, etc.), staining scores, statistical threshold, but no headline numerical result for main finding. User explicitly if no number for registered target set number_stated false parent_value 0 unit/evidence empty, target_result say what text does state instead. Need output valid JSON schema. Need ensure evidence empty string. target_result concise exact? "The text states that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL." Could quote exact wording likely. Need determine maybe headline number is absent because source truncated paper and no results. Registered target is generic "the headline numerical result the paper states for its main finding"; source has no number tied to conclusion. So false. Need perhaps target_result: "The paper states: “Elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.”" This says what text states instead. JSON only. Parent_value 0. Unit "". Evidence "". number_stated false. Ensure no extra properties.</think> {"parent_value":0,"unit":"","evidence":"","target_result":"The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.","number_stated":false}
reading object · 6 fields
parent_value
0
unit
evidence
target_result
The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.
number_stated
false
source_locator
null
recorded_at
2026-10-31T15:18:58.428932+00:00
agreement
true
disagreements object · 3 fields
target_result object · 3 fields
minimax
unknown
minimax_alt
Unclear: the supplied text states no numerical result for the main finding. The qualitative headline finding is that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.
decisive
false
physical_methods object · 3 fields
minimax array · 3 items
[0]
Immunohistochemistry
[1]
Cell Counting Kit-8
[2]
Flow cytometry
minimax_alt array · 3 items
[0]
Immunohistochemistry for CDK1 protein expression
[1]
Cell Counting Kit-8 assay of DLBCL cell growth
[2]
Annexin V-FITC/PI flow cytometry for cell death and apoptosis
decisive
false
analysis_methods object · 3 fields
minimax array · 7 items
[0]
Mann–‒Whitney U test
[1]
Chi-squared test
[2]
Kaplan–‒Meier analysis
[3]
Log-rank test
[4]
X-tile
[5]
Univariate Cox proportional hazards model
[6]
Multivariate Cox proportional hazards model
minimax_alt array · 8 items
[0]
Mann–‒Whitney U test
[1]
Chi-squared test
[2]
Kaplan-Meier analysis
[3]
Kaplan–‒Meier survival curves
[4]
Log-rank test
[5]
X-tile cutoff analysis
[6]
Univariate Cox proportional hazards modeling
[7]
Multivariate Cox proportional hazards modeling
decisive
false
agreement_basis object · 2 fields
policy
decisive_fields
decisive_fields array · 4 items
[0]
work_type
[1]
number_stated
[2]
parent_value
[3]
unit
blinded
true
human_critique object · 5 fields
status
not_run
reviewer
null
signed_at
null
conflict_checked
false
commentary
null
stages array · 7 items
[0] object · 4 fields
key
target_materials
status
pending
reason
null
evidence
null
[1] object · 4 fields
key
independent_readings
status
passed
reason
The independent readings are incomplete or disagree; the source evidence must resolve the difference.
evidence object · 1 field
provider_errors array · 0 items
[2] object · 4 fields
key
source_resolution
status
pending
reason
null
evidence
null
[3] object · 4 fields
key
protocol_reconstruction
status
pending
reason
null
evidence
null
[4] object · 4 fields
key
control_execution
status
pending
reason
null
evidence
null
[5] object · 4 fields
key
control_comparison
status
pending
reason
null
evidence
null
[6] object · 4 fields
key
publication
status
pending
reason
null
evidence
null
gaps array · 2 items
[0]
review.human_critique
[1]
review.machine_critique.passed
execution object · 5 fields
state
absent
status
not_run
mode
null
runs array · 0 items
gaps array · 1 item
[0]
execution.not_run
provenance object · 7 fields
entities array · 1 item
[0] object · 3 fields
id
package:bf1bb8e478c0129ac1fc30590aba49ebc5c9738318bf5fd3ea918d0d339c0ffd
type
sep_package
label
SEP v1 package for pmid:39773464
activities array · 1 item
[0] object · 4 fields
id
activity:conversion:pmid:39773464
type
conversion
used array · 1 item
[0]
package:bf1bb8e478c0129ac1fc30590aba49ebc5c9738318bf5fd3ea918d0d339c0ffd
agent
agent:corpus-assay-engine
agents array · 3 items
[0] object · 3 fields
id
agent:minimax
type
model
label
minimax
[1] object · 3 fields
id
agent:minimax_alt
type
model
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minimax_alt
[2] object · 3 fields
id
agent:corpus-assay-engine
type
software
label
Corpus assay engine
source_run_id
run-20261023T122449232913
dsl_catalogue_fingerprint
343fb30756ba6ec3
capability_table_fingerprint
2cb3e42f047d2ecf
snapshot_id
ba34b49490d9bfaf
lineage object · 4 fields
parent_id
pmid:39773464
parent_hash
sha256:05347ee0f8c9b96c9446b858cffc1621a1a5d1fd8c0908e96be72b7e12180627
fork_of
null
gaps array · 13 items
[0]
abstract
[1]
asset:source:pmid:39773464 not verified
[2]
authors
[3]
capability
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corpus_record_absent
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execution.not_run
[6]
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review.human_critique
[8]
review.machine_critique.passed
[9]
step:obtain_source_data blocked on data:not_downloaded
[10]
step:run_analysis blocked on no owned computational capability is bound to this experiment
[11]
step:run_analysis input 'materials:the source data behind the published result in pmid:39773464' does not resolve to a declared asset
[12]
targets
Complete file
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"order": 3, "name": "Run the analysis programme", "kind": "analysis", "state": "blocked", "blocked_on": "no owned computational capability is bound to this experiment", "description": "Re-run the paper's analysis on the source data and produce the registered result. | SEP input not carried into the asset list: materials:the source data behind the published result in pmid:39773464", "duration_hours": null, "parameters": {}, "inputs": [], "outputs": ["the registered result"], "instruments": [], "reagents": []}], "materials": [], "instruments": [], "reagents": [], "conditions": {}, "gaps": ["step:obtain_source_data blocked on data:not_downloaded", "step:run_analysis blocked on no owned computational capability is bound to this experiment", "step:run_analysis input 'materials:the source data behind the published result in pmid:39773464' does not resolve to a declared asset"]}, "data": {"state": "partial", "assets": [{"id": "source:pmid:39773464", "role": "manuscript", "format": "xml", "media_type": "application/xml", "uri": "https://doi.org/10.1186/s12885-024-13388-y", "sha256": "sha256:e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212", "bytes": null, "access": "open", "state": "resolved", "reader": null, "reader_status": "reader_required", "identifier": "10.1186/s12885-024-13388-y", "version": null, "note": "Source read by the package builder: full_text.", "structure": {"access_state": "full_text"}}, {"id": "asset:table:pmid:39773464:1", "role": "table", "format": "jats-table", "media_type": "application/vnd.jats.table+json", "uri": null, "sha256": "sha256:c4261054075163b3a02ae22826b6194d38ad119cada33183caad086c1aafe97f", "bytes": 1636, "access": "open", "state": "verified", "reader": "read_table", "reader_status": "available", "identifier": "section[12]/table-wrap[1]#Tab1", "version": null, "note": "Characteristics of 306 subjects with diffuse large B-cell lymphoma (DLBCL)", "structure": {"pmcid": "PMC11705832", "section_index": 12, "section_title": "CDK1 expression and characteristics of DLBCL patients", "row_count": 31, "column_count": 5}, "table": {"label": "Table 1", "caption": "Characteristics of 306 subjects with diffuse large B-cell lymphoma (DLBCL)", "rows": [["Characteristics", "Total(n = 306)", "CDK1-high(n = 45)", "CDK1-low (n = 261)", "P"], ["Gender(%)", "", "", "", "0.674"], ["male", "172(56.21)", "24(53.33)", "148(56.70)", ""], ["female", "134(43.79)", "21(46.67)", "113(43.30)", ""], ["Age(%)", "", "", "", "0.429"], ["<60", "139(45.42)", "18(40)", "121(46.36)", ""], ["≥ 60", "167(54.58)", "27(60)", "140(53.64)", ""], ["Cell of origin(%)", "", "", "", "0.104"], ["GCB", "134(43.79)", "26(57.78)", "108(41.38)", ""], ["ABC", "125(40.85)", "15(33.33)", "110(42.15)", ""], ["UC", "47(15.36)", "4(8.89)", "43(16.48)", ""], ["Count of extranodalinvasion(%)", "", "", "", "0.100"], ["0", "190(62.09)", "23(51.11)", "167(63.98)", ""], ["≥ 1", "116(30.39)", "22(48.89)", "94(36.02)", ""], ["LDH ratio(%)", "", "", "", "0.022"], ["≤ 1", "157(51.31)", "16(35.56)", "141(54.02)", ""], [">1", "149(48.69)", "29(64.44)", "120(45.98)", ""], ["Ann-Arbor stage(%)", "", "", "", "0.307"], ["I", "50(16.34)", "7(15.57)", "43(16.48)", ""], ["II", "94(30.71)", "14(31.11)", "80(30.65)", ""], ["III", "69(22.55)", "6(13.33)", "63(24.14)", ""], ["IV", "93(30.39)", "18(40)", "75(28.74)", ""], ["ECOG(%)", "", "", "", "0.386"], ["0", "69(22.55)", "7(15.56)", "62(23.75)", ""], ["1", "162(52.94)", "24(53.33)", "138(52.87)", ""], ["2", "48(15.69)", "7(15.56)", "41(15.71)", ""], ["3", "22(7.19)", "5(11.11)", "17(6.51)", ""], ["4", "5(1.63)", "2(4.44)", "3(1.15)", ""], ["Treatment(%)", "", "", "", "0.183"], ["CHOP-like", "142(46.41)", "25(55.56)", "117(44.83)", ""], ["R-CHOP-like", "164(53.59)", "20(44.44)", "144(55.17)", ""]], "row_count": 31, "column_count": 5, "numeric_cells": 88, "header_rows": 1, "locator": "section[12]/table-wrap[1]#Tab1"}}], "gaps": ["asset:source:pmid:39773464 not verified"]}, "analysis": {"state": "absent", "methods": [], "targets": [], "gaps": ["method", "targets"]}, "capability": {"state": "absent", "requirements": [], "gaps": ["capability"]}, "readiness": {"state": "partial", "tier": null, "blocking_axis": null, "blocked_on": null, "axes": {}, "can_run": {"dsl_operations": [], "assets": ["source:pmid:39773464", "asset:table:pmid:39773464:1"], "steps": ["read_published_estimate"]}, "must_build": {"dsl_operations": [], "converters": [], "readers": ["xml"], "capabilities": [], "data_gaps": ["source:pmid:39773464"]}, "gaps": ["corpus_record_absent"]}, "review": {"state": "partial", "machine_critique": {"status": "passed", "providers": [{"provider": "minimax", "model": "MiniMax-M3.1-Flash", "prompt_version": "full-text-reading-v1", "prompt_hash": "ba2b28d06d0423fae4bcba15c6fe1e70c0024d80eaffa1b19b2f862d51f32a37", "source_hash": "e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212", "raw_response_sha256": "sha256:75ae0945f8b1a3f536253c70e2d7dfb39eacbfd7961c715da6776220309357d4", "raw_response_chars": 4612}, {"provider": "minimax_alt", "model": "MiniMax-M3", "prompt_version": "full-text-reading-v1", "prompt_hash": "b7068d9947246be683657417e8caafbce57d24364d7b46bfbea2f9518b25038d", "source_hash": "e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212", "raw_response_sha256": "sha256:9091ae7a3b384543e0bfc2496ec07b35a15bd689804ea5490241da964476d52f", "raw_response_chars": 49197}], "target_providers": [{"provider": "minimax", "model": "MiniMax-M3.1-Flash", "prompt_version": "replication-target-v2", "prompt_hash": "f22c21d028ec1f95ab3c2e61dcddabc382a204af0d9d9646843714767564f533", "source_hash": "e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212", "raw_response": "{\"parent_value\":0,\"unit\":\"\",\"evidence\":\"\",\"target_result\":\"The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with diffuse large B-cell lymphoma, but it does not state a numerical result for this main finding.\",\"number_stated\":false}", "reading": {"parent_value": 0, "unit": "", "evidence": "", "target_result": "The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with diffuse large B-cell lymphoma, but it does not state a numerical result for this main finding.", "number_stated": false, "source_locator": null}, "recorded_at": "2026-10-31T15:19:00.404573+00:00"}, {"provider": "minimax_alt", "model": "MiniMax-M3", "prompt_version": "replication-target-v2", "prompt_hash": "48bcb7c9b888839624d74d0a24a0b6147386f6958c7915e8e08a452b6e9c8dbb", "source_hash": "e494a7cc0b3a5a569c70bf56d7a1975a008f7d1cfe35fe3682782620411a3212", "raw_response": "<think>We need answer JSON only. Need interpret task carefully. Need find single numerical result replication registered target headline numerical result paper states for main finding. Source text provided seems abstract/methods without actual specific main finding numeric values. It has methodological numbers (1×106 cells/well, 10 µM, 24h, etc.), staining scores, statistical threshold, but no headline numerical result for main finding. User explicitly if no number for registered target set number_stated false parent_value 0 unit/evidence empty, target_result say what text does state instead. Need output valid JSON schema. Need ensure evidence empty string. target_result concise exact? \"The text states that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.\" Could quote exact wording likely. Need determine maybe headline number is absent because source truncated paper and no results. Registered target is generic \"the headline numerical result the paper states for its main finding\"; source has no number tied to conclusion. So false.\n\nNeed perhaps target_result: \"The paper states: “Elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.”\" This says what text states instead. JSON only. Parent_value 0. Unit \"\". Evidence \"\". number_stated false. Ensure no extra properties.</think>\n\n{\"parent_value\":0,\"unit\":\"\",\"evidence\":\"\",\"target_result\":\"The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.\",\"number_stated\":false}", "reading": {"parent_value": 0, "unit": "", "evidence": "", "target_result": "The paper states that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.", "number_stated": false, "source_locator": null}, "recorded_at": "2026-10-31T15:18:58.428932+00:00"}], "agreement": true, "disagreements": {"target_result": {"minimax": "unknown", "minimax_alt": "Unclear: the supplied text states no numerical result for the main finding. The qualitative headline finding is that elevated CDK1 levels are correlated with poor prognosis in patients with DLBCL.", "decisive": false}, "physical_methods": {"minimax": ["Immunohistochemistry", "Cell Counting Kit-8", "Flow cytometry"], "minimax_alt": ["Immunohistochemistry for CDK1 protein expression", "Cell Counting Kit-8 assay of DLBCL cell growth", "Annexin V-FITC/PI flow cytometry for cell death and apoptosis"], "decisive": false}, "analysis_methods": {"minimax": ["Mann–‒Whitney U test", "Chi-squared test", "Kaplan–‒Meier analysis", "Log-rank test", "X-tile", "Univariate Cox proportional hazards model", "Multivariate Cox proportional hazards model"], "minimax_alt": ["Mann–‒Whitney U test", "Chi-squared test", "Kaplan-Meier analysis", "Kaplan–‒Meier survival curves", "Log-rank test", "X-tile cutoff analysis", "Univariate Cox proportional hazards modeling", "Multivariate Cox proportional hazards modeling"], "decisive": false}}, "agreement_basis": {"policy": "decisive_fields", "decisive_fields": ["work_type", "number_stated", "parent_value", "unit"]}, "blinded": true}, "human_critique": {"status": "not_run", "reviewer": null, "signed_at": null, "conflict_checked": false, "commentary": null}, "stages": [{"key": "target_materials", "status": "pending", "reason": null, "evidence": null}, {"key": "independent_readings", "status": "passed", "reason": "The independent readings are incomplete or disagree; the source evidence must resolve the difference.", "evidence": {"provider_errors": []}}, {"key": "source_resolution", "status": "pending", "reason": null, "evidence": null}, {"key": "protocol_reconstruction", "status": "pending", "reason": null, "evidence": null}, {"key": "control_execution", "status": "pending", "reason": null, "evidence": null}, {"key": "control_comparison", "status": "pending", "reason": null, "evidence": null}, {"key": "publication", "status": "pending", "reason": null, "evidence": null}], "gaps": ["review.human_critique", "review.machine_critique.passed"]}, "execution": {"state": "absent", "status": "not_run", "mode": null, "runs": [], "gaps": ["execution.not_run"]}, "provenance": {"entities": [{"id": "package:bf1bb8e478c0129ac1fc30590aba49ebc5c9738318bf5fd3ea918d0d339c0ffd", "type": "sep_package", "label": "SEP v1 package for pmid:39773464"}], "activities": [{"id": "activity:conversion:pmid:39773464", "type": "conversion", "used": ["package:bf1bb8e478c0129ac1fc30590aba49ebc5c9738318bf5fd3ea918d0d339c0ffd"], "agent": "agent:corpus-assay-engine"}], "agents": [{"id": "agent:minimax", "type": "model", "label": "minimax"}, {"id": "agent:minimax_alt", "type": "model", "label": "minimax_alt"}, {"id": "agent:corpus-assay-engine", "type": "software", "label": "Corpus assay engine"}], "source_run_id": "run-20261023T122449232913", "dsl_catalogue_fingerprint": "343fb30756ba6ec3", "capability_table_fingerprint": "2cb3e42f047d2ecf", "snapshot_id": "ba34b49490d9bfaf"}, "lineage": {"parent_id": "pmid:39773464", "parent_hash": "sha256:05347ee0f8c9b96c9446b858cffc1621a1a5d1fd8c0908e96be72b7e12180627", "fork_of": null, "generation": 2}, "gaps": ["abstract", "asset:source:pmid:39773464 not verified", "authors", "capability", "corpus_record_absent", "execution.not_run", "method", "review.human_critique", "review.machine_critique.passed", "step:obtain_source_data blocked on data:not_downloaded", "step:run_analysis blocked on no owned computational capability is bound to this experiment", "step:run_analysis input 'materials:the source data behind the published result in pmid:39773464' does not resolve to a declared asset", "targets"]}