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pmid:40421173

Investigation of the Significance of Blood Signatures on Sepsis-Induced Acute Lung Injury in Sepsis Within 24 Hours.

International journal of genomics · 2025 doi:10.1155/ijog/5684300

Paper

partial

Experiment

partial

Data

partial

Analysis

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Execution

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Record details sci_version · id · kind · revision · content_hash · schema · created_at · updated_at · generator
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pmid:40421173
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science-record
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https://corpus.bntrg.co.uk/sci/1.0/sci.schema.json
created_at
2026-11-01T10:25:51Z
updated_at
2026-11-01T14:01:41Z
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corpus-assay-engine
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urn:bntrg:sep:1.0.0
paper object · 10 fields
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partial
title
Investigation of the Significance of Blood Signatures on Sepsis-Induced Acute Lung Injury in Sepsis Within 24 Hours.
doi
10.1155/ijog/5684300
pmid
40421173
authors
null
journal
International journal of genomics
year
2025
abstract
null
claims array · 1 item
[0] object · 6 fields
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the headline numerical result the paper states for its main finding
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null
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null
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null
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null
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abstract
[1]
authors
experiment object · 8 fields
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the headline numerical result the paper states for its main finding
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Read the published estimate and its interval from the source
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other
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The number a replication must land on, and the sentence it came from.
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[0]
source:pmid:40421173
outputs array · 1 item
[0]
the published estimate, its unit and its interval
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Obtain the source data behind the published result
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data-preparation
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The published result cannot be recomputed without the data the paper analysed.
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the source data with its provenance
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Run the analysis programme
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no owned computational capability is bound to this experiment
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Re-run the paper's analysis on the source data and produce the registered result. | SEP input not carried into the asset list: materials:the source data behind the published result in pmid:40421173
parameters object · 0 fields
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the registered result
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Source read by the package builder: full_text.
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Descriptive data of the mRNA study groups in GSE95233.
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PMC12105892
section_index
3
section_title
2.1. Data Acquisition and Processing
row_count
4
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table object · 8 fields
label
Table 1
caption
Descriptive data of the mRNA study groups in GSE95233.
rows array · 4 items
[0] array · 4 items
[0]
[1]
Patients ( n = 29)
[2]
Health control ( n = 22)
[3]
p value
[1] array · 4 items
[0]
Ages (years)
[1]
57.13 ± 6.98
[2]
59.16 ± 8.30
[3]
0.22
[2] array · 4 items
[0]
Male/female ratio
[1]
11/18
[2]
10/12
[3]
0.47
[3] array · 4 items
[0]
Time of sample collection
[1]
Day 1
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[3]
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section[3]/table-wrap[1]#tab1
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Descriptive data of the mRNA study groups in GSE54514.
structure object · 5 fields
pmcid
PMC12105892
section_index
3
section_title
2.1. Data Acquisition and Processing
row_count
4
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table object · 8 fields
label
Table 2
caption
Descriptive data of the mRNA study groups in GSE54514.
rows array · 4 items
[0] array · 4 items
[0]
[1]
Patients ( n = 35)
[2]
Health control ( n = 18)
[3]
p value
[1] array · 4 items
[0]
Ages (years)
[1]
50.6 ± 4.35
[2]
54.78 ± 5.33
[3]
0.14
[2] array · 4 items
[0]
Male/female ratio
[1]
21/15
[2]
8/10
[3]
0.86
[3] array · 4 items
[0]
Time of sample collection
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Day 1
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[3]
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section[3]/table-wrap[2]#tab2
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Primer sequence of gene.
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pmcid
PMC12105892
section_index
12
section_title
2.10. Real-Time qRT-PCR Validation
row_count
3
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3
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Table 3
caption
Primer sequence of gene.
rows array · 3 items
[0] array · 3 items
[0]
Gene
[1]
Forward primer
[2]
Reverse primer
[1] array · 3 items
[0]
SLPI
[1]
AGAAAGACACTTGCCCAGGA
[2]
CCTGAACCCTACTCCAAGCA
[2] array · 3 items
[0]
GAPDH
[1]
GATGGTGATGGGTTTCCCGT
[2]
AGTGCCAGCCTCGTCTCATA
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section[12]/table-wrap[1]#tab3
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KEGG-enriched items of DEGs.
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pmcid
PMC12105892
section_index
20
section_title
3.2. GO and KEGG Pathway Analyses of DEGs
row_count
43
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7
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Table 4
caption
KEGG-enriched items of DEGs.
rows array · 43 items
[0] array · 7 items
[0]
ID
[1]
Description
[2]
GeneRatio
[3]
p value
[4]
p .adjust
[5]
q value
[6]
Count
[1] array · 7 items
[0]
hsa04659
[1]
Th17 cell differentiation
[2]
37/515
[3]
2.78e − 19
[4]
8.83e − 17
[5]
7.28e − 17
[6]
37
[2] array · 7 items
[0]
hsa04640
[1]
Hematopoietic cell lineage
[2]
34/515
[3]
7.53e − 18
[4]
1.20e − 15
[5]
9.87e − 16
[6]
34
[3] array · 7 items
[0]
hsa04658
[1]
Th1 and Th2 cell differentiation
[2]
32/515
[3]
4.69e − 17
[4]
4.97e − 15
[5]
4.10e − 15
[6]
32
[4] array · 7 items
[0]
hsa05321
[1]
Inflammatory bowel disease
[2]
22/515
[3]
7.65e − 12
[4]
6.08e − 10
[5]
5.01e − 10
[6]
22
[5] array · 7 items
[0]
hsa05145
[1]
Toxoplasmosis
[2]
27/515
[3]
1.83e − 10
[4]
1.02e − 08
[5]
8.39e − 09
[6]
27
[6] array · 7 items
[0]
hsa05235
[1]
PD-L1 expression and PD-1 checkpoint pathway in cancer
[2]
24/515
[3]
1.92e − 10
[4]
1.02e − 08
[5]
8.39e − 09
[6]
24
[7] array · 7 items
[0]
hsa05310
[1]
Asthma
[2]
13/515
[3]
7.67e − 09
[4]
3.48e − 07
[5]
2.87e − 07
[6]
13
[8] array · 7 items
[0]
hsa04672
[1]
Intestinal immune network for IgA production
[2]
16/515
[3]
1.04e − 08
[4]
4.14e − 07
[5]
3.41e − 07
[6]
16
[9] array · 7 items
[0]
hsa05330
[1]
Allograft rejection
[2]
14/515
[3]
1.49e − 08
[4]
5.24e − 07
[5]
4.32e − 07
[6]
14
[10] array · 7 items
[0]
hsa04612
[1]
Antigen processing and presentation
[2]
20/515
[3]
1.65e − 08
[4]
5.24e − 07
[5]
4.32e − 07
[6]
20
[11] array · 7 items
[0]
hsa04660
[1]
T cell receptor signaling pathway
[2]
25/515
[3]
3.12e − 08
[4]
9.03e − 07
[5]
7.44e − 07
[6]
25
[12] array · 7 items
[0]
hsa05332
[1]
Graft-versus-host disease
[2]
14/515
[3]
6.53e − 08
[4]
1.73e − 06
[5]
1.43e − 06
[6]
14
[13] array · 7 items
[0]
hsa05140
[1]
Leishmaniasis
[2]
19/515
[3]
7.39e − 08
[4]
1.81e − 06
[5]
1.49e − 06
[6]
19
[14] array · 7 items
[0]
hsa05320
[1]
Autoimmune thyroid disease
[2]
14/515
[3]
1.62e − 06
[4]
3.67e − 05
[5]
3.03e − 05
[6]
14
[15] array · 7 items
[0]
hsa05166
[1]
Human T cell leukemia virus 1 infection
[2]
32/515
[3]
2.47e − 06
[4]
5.23e − 05
[5]
4.31e − 05
[6]
32
[16] array · 7 items
[0]
hsa05169
[1]
Epstein–Barr virus infection
[2]
30/515
[3]
2.74e − 06
[4]
5.44e − 05
[5]
4.49e − 05
[6]
30
[17] array · 7 items
[0]
hsa04940
[1]
Type I diabetes mellitus
[2]
12/515
[3]
4.83e − 06
[4]
9.04e − 05
[5]
7.45e − 05
[6]
12
[18] array · 7 items
[0]
hsa05416
[1]
Viral myocarditis
[2]
15/515
[3]
6.52e − 06
[4]
0.000115169
[5]
9.49e − 05
[6]
15
[19] array · 7 items
[0]
hsa04514
[1]
Cell adhesion molecules
[2]
24/515
[3]
1.67e − 05
[4]
0.000279531
[5]
0.000230398
[6]
24
[20] array · 7 items
[0]
hsa05152
[1]
Tuberculosis
[2]
26/515
[3]
2.10e − 05
[4]
0.000333494
[5]
0.000274876
[6]
26
[21] array · 7 items
[0]
hsa05323
[1]
Rheumatoid arthritis
[2]
17/515
[3]
2.82e − 05
[4]
0.00042691
[5]
0.000351872
[6]
17
[22] array · 7 items
[0]
hsa04064
[1]
NF-kappa B signaling pathway
[2]
18/515
[3]
3.55e − 05
[4]
0.000513801
[5]
0.00042349
[6]
18
[23] array · 7 items
[0]
hsa05150
[1]
Staphylococcus aureus infection
[2]
17/515
[3]
4.31e − 05
[4]
0.000596384
[5]
0.000491558
[6]
17
[24] array · 7 items
[0]
hsa05340
[1]
Primary immunodeficiency
[2]
10/515
[3]
5.27e − 05
[4]
0.000698037
[5]
0.000575343
[6]
10
[25] array · 7 items
[0]
hsa05202
[1]
Transcriptional misregulation in cancer
[2]
26/515
[3]
7.10e − 05
[4]
0.000902043
[5]
0.000743491
[6]
26
[26] array · 7 items
[0]
hsa04061
[1]
Viral protein interaction with cytokine and cytokine receptor
[2]
17/515
[3]
7.38e − 05
[4]
0.000902043
[5]
0.000743491
[6]
17
[27] array · 7 items
[0]
hsa04650
[1]
Natural killer cell–mediated cytotoxicity
[2]
20/515
[3]
9.51e − 05
[4]
0.00112018
[5]
0.000923286
[6]
20
[28] array · 7 items
[0]
hsa04380
[1]
Osteoclast differentiation
[2]
20/515
[3]
0.000130723
[4]
0.001484637
[5]
0.001223683
[6]
20
[29] array · 7 items
[0]
hsa04060
[1]
Cytokine–cytokine receptor interaction
[2]
32/515
[3]
0.00075042
[4]
0.008228742
[5]
0.006782379
[6]
32
[30] array · 7 items
[0]
hsa00512
[1]
Mucin type O-glycan biosynthesis
[2]
8/515
[3]
0.001018198
[4]
0.0107929
[5]
0.008895836
[6]
8
[31] array · 7 items
[0]
hsa05164
[1]
Influenza A
[2]
21/515
[3]
0.001191443
[4]
0.012221898
[5]
0.010073659
[6]
21
[32] array · 7 items
[0]
hsa04621
[1]
NOD-like receptor signaling pathway
[2]
22/515
[3]
0.00150978
[4]
0.015003435
[5]
0.012366287
[6]
22
[33] array · 7 items
[0]
hsa05221
[1]
Acute myeloid leukemia
[2]
11/515
[3]
0.001819445
[4]
0.017532835
[5]
0.014451096
[6]
11
[34] array · 7 items
[0]
hsa05142
[1]
Chagas disease
[2]
14/515
[3]
0.002727186
[4]
0.025507208
[5]
0.021023816
[6]
14
[35] array · 7 items
[0]
hsa04662
[1]
B cell receptor signaling pathway
[2]
12/515
[3]
0.003842922
[4]
0.034233572
[5]
0.02821635
[6]
12
[36] array · 7 items
[0]
hsa04145
[1]
Phagosome
[2]
18/515
[3]
0.003875499
[4]
0.034233572
[5]
0.02821635
[6]
18
[37] array · 7 items
[0]
hsa00500
[1]
Starch and sucrose metabolism
[2]
7/515
[3]
0.004660146
[4]
0.040052069
[5]
0.033012132
[6]
7
[38] array · 7 items
[0]
hsa04062
[1]
Chemokine signaling pathway
[2]
21/515
[3]
0.004904958
[4]
0.041046755
[5]
0.033831982
[6]
21
[39] array · 7 items
[0]
hsa04210
[1]
Apoptosis
[2]
16/515
[3]
0.00668656
[4]
0.054521185
[5]
0.044938017
[6]
16
[40] array · 7 items
[0]
hsa05135
[1]
Yersinia infection
[2]
16/515
[3]
0.007169021
[4]
0.055603623
[5]
0.045830196
[6]
16
[41] array · 7 items
[0]
hsa05322
[1]
Systemic lupus erythematosus
[2]
16/515
[3]
0.007169021
[4]
0.055603623
[5]
0.045830196
[6]
16
[42] array · 7 items
[0]
hsa05170
[1]
Human immunodeficiency virus 1 infection
[2]
22/515
[3]
0.007495387
[4]
0.056750784
[5]
0.046775721
[6]
22
locator
section[20]/table-wrap[1]#tab4
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asset:table:pmid:40421173:2
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asset:table:pmid:40421173:3
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source:pmid:40421173
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HTTP Error 429: Too Many Requests
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package:d28a9556073c73e6e4ff6bae4947485eba40a9955328df033c1f0553c6a8ed4b
type
sep_package
label
SEP v1 package for pmid:40421173
activities array · 1 item
[0] object · 4 fields
id
activity:conversion:pmid:40421173
type
conversion
used array · 1 item
[0]
package:d28a9556073c73e6e4ff6bae4947485eba40a9955328df033c1f0553c6a8ed4b
agent
agent:corpus-assay-engine
agents array · 1 item
[0] object · 3 fields
id
agent:corpus-assay-engine
type
software
label
Corpus assay engine
source_run_id
run-20261023T122449232913
dsl_catalogue_fingerprint
343fb30756ba6ec3
capability_table_fingerprint
2cb3e42f047d2ecf
snapshot_id
ba34b49490d9bfaf
lineage object · 4 fields
parent_id
pmid:40421173
parent_hash
sha256:163ba3254a8b751a284047cac7a203632ada9e1bbc783079997f448160ab0391
fork_of
null
gaps array · 14 items
[0]
abstract
[1]
asset:source:pmid:40421173 not verified
[2]
authors
[3]
capability
[4]
corpus_record_absent
[5]
execution.not_run
[6]
method
[7]
review.human_critique
[8]
review.machine_critique.blocked
[9]
review.machine_critique.providers
[10]
step:obtain_source_data blocked on data:not_downloaded
[11]
step:run_analysis blocked on no owned computational capability is bound to this experiment
[12]
step:run_analysis input 'materials:the source data behind the published result in pmid:40421173' does not resolve to a declared asset
[13]
targets
Complete file
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